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28.07.2017 | Brief Report

Metastatic malignant PEComa of the leg with identification of ATRX mutation by next-generation sequencing

verfasst von: Hussein Alnajar, Arlen Brickman, Lela Buckingham, Leonidas D. Arvanitis

Erschienen in: Virchows Archiv | Ausgabe 3/2018

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Excerpt

The α-thalassemia mental retardation X-linked protein (ATRX) is a member of the Switch 2, sucrose non-fermenting 2 family (SWI2/SNF2) that encodes chromatin remodeling proteins. These proteins have an important role in the regulation of histone variant H3.3 deposition [1, 2]. …
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Metadaten
Titel
Metastatic malignant PEComa of the leg with identification of ATRX mutation by next-generation sequencing
verfasst von
Hussein Alnajar
Arlen Brickman
Lela Buckingham
Leonidas D. Arvanitis
Publikationsdatum
28.07.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Virchows Archiv / Ausgabe 3/2018
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-017-2208-x

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