nach oben

Journal of Behavioral Medicine

Erschienen in:

17.05.2018

Methamphetamine-associated dysregulation of the hypothalamic–pituitary–thyroid axis

verfasst von: Deborah L. Jones, Adam W. Carrico, Suat Babayigit, Violeta J. Rodriguez, Carlos Aguila, Mahendra Kumar

Erschienen in: Journal of Behavioral Medicine | Ausgabe 6/2018

Einloggen, um Zugang zu erhalten

Abstract

Methamphetamine and HIV impair thyroid function, but few studies have investigated their combined effects on thyroid dysregulation. This study examined the associations of methamphetamine use alone and in combination with HIV on thyroid function among men in South Florida. Measures of thyroid function in methamphetamine-using, HIV-infected (METH+HIV+; n = 127) and HIV-negative (METH+HIV−; n = 46) men who have sex with men (MSM) were compared to non-methamphetamine-using, HIV-negative men (METH−HIV−; n = 136). Thyroid function was dysregulated in methamphetamine-using MSM, irrespective of HIV status. Both meth-using groups had greater odds of abnormal thyroid stimulating hormone levels and significantly higher mean free triiodothyronine (T3) levels. Elevated free T3 was associated with greater depressive symptoms. Overall, outcomes have important implications for assessment of thyroid function in methamphetamine users, particularly among those presenting with depression.

Baker, T. B., Piper, M. E., McCarthy, D. E., Majeskie, M. R., & Fiore, M. C. (2004). Addiction motivation reformulated: An affective processing model of negative reinforcement. Psychological Review, 111, 33–51. https://doi.org/10.1037/0033-295X.111.1.33 CrossRefPubMed

Bernstein, D. P., Ahluvalia, T., Pogge, D., & Handelsman, L. (1997). Validity of the Childhood Trauma Questionnaire in an adolescent psychiatric population. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 340–348. https://doi.org/10.1097/00004583-199703000-00012 CrossRefPubMed

Carrico, A. W. (2011). Substance use and HIV disease progression in the HAART era: Implications for the primary prevention of HIV. Life Sciences, 88, 940–947. https://doi.org/10.1016/j.lfs.2010.10.002 CrossRefPubMed

Carrico, A. W., Riley, E. D., Johnson, M. O., Charlebois, E. D., Neilands, T. B., Remien, R. H., et al. (2011). Psychiatric risk factors for HIV disease progression: The role of inconsistent patterns of antiretroviral therapy utilization. Journal of Acquired Immune Deficiency Syndromes, 56, 146–150. https://doi.org/10.1097/QAI.0b013e318201df63 CrossRefPubMed

Carrico, A. W., Rodriguez, V. J., Jones, D. L., & Kumar, M. K. (2017). Short circuit: Disaggregation of adrenocorticotropic hormone and cortisol levels in HIV-positive, methamphetamine-using men who have sex with men. Human Psychopharmacology Clinical and Experimental. https://doi.org/10.1002/hup.2645 CrossRefPubMed

Carrico, A. W., Shoptaw, S., Cox, C., Stall, R., Li, X., Ostrow, D. G., et al. (2014). Stimulant use and progression to AIDS or mortality after the initiation of highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 67, 508–513. https://doi.org/10.1097/QAI.0000000000000364 CrossRefPubMed

Carrico, A. W., Zepf, R., Meanley, S., Batchelder, A., & Stall, R. (2016). When the party is over: A systematic review of behavioral interventions for substance-using men who have sex with men. Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/QAI.0000000000001102 CrossRefPubMed

Colfax, G., Santos, G. M., Chu, P., Vittinghoff, E., Pluddemann, A., Kumar, S., et al. (2010). Amphetamine-group substances and HIV. Lancet, 376, 458–474. https://doi.org/10.1016/S0140-6736(10)60753-2 CrossRefPubMed

Ellis, R. J., Childers, M. E., Cherner, M., Lazzaretto, D., Letendre, S., Grant, I., et al. (2003). Increased human immunodeficiency virus loads in active methamphetamine users are explained by reduced effectiveness of antiretroviral therapy. Journal of Infectious Diseases, 188, 1820–1826. https://doi.org/10.1086/379894 CrossRefPubMed

Finlayson, T. J., Le, B., Smith, A., Bowles, K., Cribbin, M., Miles, I., et al. (2011). HIV risk, prevention, and testing behaviors among men who have sex with men–National HIV Behavioral Surveillance System, 21 US cities, United States, 2008. MMWR Surveill Summ, 60, 1–34.PubMed

First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2002). Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition With Psychotic Screen (SCID-I/P W/ PSY SCREEN). New York: Biometrics Research, New York State Psychiatric Institute.

Gozashti, M. H., Mohammadzadeh, E., Divsalar, K., & Shokoohi, M. (2014). The effect of opium addiction on thyroid function tests. Journal of Diabetes and Metabolic Disorders, 13, 5.CrossRef

Hage, M. P., & Azar, S. T. (2012). The link between thyroid function and depression. Journal of Thyroid Research, 2012, 1–8.CrossRef

Hoffmann, C. J., & Brown, T. T. (2007). Thyroid function abnormalities in HIV-infected patients. Clinical Infectious Diseases, 45, 488–494. https://doi.org/10.1086/519978 CrossRefPubMed

Ji, S., Jin, C., Hoxtermann, S., Fuchs, W., Xie, T., Lu, X., et al. (2016). Prevalence and influencing factors of thyroid dysfunction in HIV-infected patients. BioMed Research International, 2016, 3874257. https://doi.org/10.1155/2016/3874257 CrossRefPubMedPubMedCentral

Koblin, B. A., Husnik, M. J., Colfax, G., Huang, Y., Madison, M., Mayer, K., et al. (2006). Risk factors for HIV infection among men who have sex with men. AIDS, 20, 731–739. https://doi.org/10.1097/01.aids.0000216374.61442.55 CrossRefPubMed

Li, S., Yan, S. Y., Bao, Y., Lian, Z., Qu, Z., Wu, Y. C., et al. (2013). Depression and alterations in hypothalamic–pituitary–adrenal and hypothalamic–pituitary–thyroid axis function in male abstinent methamphetamine abusers. Human Psychopharmacology: Clinical and Experimental, 28, 477–483.CrossRef

Mayer, K. H., Skeer, M. R., O’Cleirigh, C., Goshe, B. M., & Safren, S. A. (2014). Factors associated with amplified HIV transmission behavior among American men who have sex with men engaged in care: Implications for clinical providers. Annals of Behavioral Medicine, 47, 165–171. https://doi.org/10.1007/s12160-013-9527-1 CrossRefPubMedPubMedCentral

National Drug Early Warning System (NDEWS). (2015). Annual project report. Retrieved from https://ndews.umd.edu/sites/ndews.umd.edu/files/NDEWS%20Annual%20Project%20Report%202015%20Final%20Web.pdf. Accessed March 29, 2018.

Noureldeen, A. F., Qusti, S. Y., & Khoja, G. M. (2014). Thyroid function in newly diagnosed HIV-infected patients. Toxicology and Industrial Health, 30, 919–925. https://doi.org/10.1177/0748233712466133 CrossRefPubMed

O’Cleirigh, C., Safren, S. A., & Mayer, K. H. (2012). The pervasive effects of childhood sexual abuse: Challenges for improving HIV prevention and treatment interventions. Journal of Acquired Immune Deficiency Syndromes, 59, 331–334. https://doi.org/10.1097/QAI.0b013e31824aed80 CrossRefPubMed

Oldenburg, C. E., Jain, S., Mayer, K. H., & Mimiaga, M. J. (2015). Post-exposure prophylaxis use and recurrent exposure to HIV among men who have sex with men who use crystal methamphetamine. Drug and Alcohol Dependence, 146, 75–80. https://doi.org/10.1016/j.drugalcdep.2014.11.010 CrossRefPubMed

Ostrow, D. G., Plankey, M. W., Cox, C., Li, X., Shoptaw, S., Jacobson, L. P., et al. (2009). Specific sex drug combinations contribute to the majority of recent HIV seroconversions among MSM in the MACS. Journal of Acquired Immune Deficiency Syndromes, 51, 349–355. https://doi.org/10.1097/QAI.0b013e3181a24b20 CrossRefPubMed

Parsa, A. A., & Bhangoo, A. (2013). HIV and thyroid dysfunction. Reviews in Endocrine and Metabolic Disorders, 14, 127–131. https://doi.org/10.1007/s11154-013-9248-6 CrossRefPubMed

Parsons, J. T., Grov, C., & Golub, S. A. (2012). Sexual compulsivity, co-occurring psychosocial health problems, and HIV risk among gay and bisexual men: Further evidence of a syndemic. American Journal of Public Health, 102, 156–162. https://doi.org/10.2105/AJPH.2011.300284 CrossRefPubMedPubMedCentral

Passaro, R. C., Pandhare, J., Qian, H. Z., & Dash, C. (2015). the complex interaction between methamphetamine abuse and HIV-1 pathogenesis. Journal of Neuroimmune Pharmacology, 10, 477–486.CrossRef

Pingitore, A., Landi, P., Taddei, M. C., Ripoli, A., L’Abbate, A., & Iervasi, G. (2005). Triiodothyronine levels for risk stratification of patients with chronic heart failure. American Journal of Medicine, 118, 132–136.CrossRef

Plankey, M. W., Ostrow, D. G., Stall, R., Cox, C., Li, X., Peck, J. A., et al. (2007). The relationship between methamphetamine and popper use and risk of HIV seroconversion in the multicenter AIDS cohort study. Journal of Acquired Immune Deficiency Syndromes, 45, 85–92. https://doi.org/10.1097/QAI.0b013e3180417c99 CrossRefPubMed

Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385–401.CrossRef

Zuloaga, D. G., Jacobskind, J. S., & Raber, J. (2015). Methamphetamine and the hypothalamic-pituitary-adrenal axis. Frontiers in Neuroscience, 9, 178.PubMedPubMedCentral

Zuloaga, D. G., Siegel, J. A., Acevedo, S. F., Agam, M., & Raber, J. (2013). Developmental methamphetamine exposure results in short- and long-term alterations in hypothalamic-pituitary-adrenal-axis-associated proteins. Developmental Neuroscience, 35, 338–346. https://doi.org/10.1159/000351278 CrossRefPubMed

Titel: Methamphetamine-associated dysregulation of the hypothalamic–pituitary–thyroid axis
verfasst von: Deborah L. Jones
Adam W. Carrico
Suat Babayigit
Violeta J. Rodriguez
Carlos Aguila
Mahendra Kumar
Publikationsdatum: 17.05.2018
Verlag: Springer US
Erschienen in: Journal of Behavioral Medicine / Ausgabe 6/2018
Print ISSN: 0160-7715
Elektronische ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-018-9935-6

Neu im Fachgebiet Psychiatrie

23.04.2024 | Demenz | Nachrichten

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Methamphetamine-associated dysregulation of the hypothalamic–pituitary–thyroid axis

Abstract

Neu im Fachgebiet Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Psychiatrie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 6/2018

Parents have both implicit and explicit biases against children with obesity

Dismantling the theory of planned behavior: evaluating the relative effectiveness of attempts to uniquely change attitudes, norms, and perceived behavioral control

Independent and relative effects of stress, depressive symptoms, and affect on college students’ daily health behaviors

Self-regulation and obesity: the role of executive function and delay discounting in the prediction of weight loss

Self-compassion, chronic age-related stressors, and diurnal cortisol secretion in older adulthood

Targeting and tailoring message-framing: the moderating effect of racial identity on receptivity to colorectal cancer screening among African–Americans

Neu im Fachgebiet Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Psychiatrie