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Inflammation
Erschienen in: Inflammation 2/2017

15.12.2016 | REVIEW

MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases

verfasst von: Wu Xiaoyan, Eva Maria Arriero Pais, Li Lan, Chen Jingrui, Miao Lin, Patrick Asare Fordjour, Fan Guanwei

Erschienen in: Inflammation | Ausgabe 2/2017

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Abstract

An increasing number of diseases are being newly closely associated with inflammation, where microRNAs seem to play a critical role in the whole disease process from initiation to development. MicroRNAs are small non-coding RNAs that govern gene expression and modulation by means of mRNA degradation or translational repression. After several profound research studies, new correlations between microRNA-155 and inflammation-related diseases are strongly emerging. Hence, we review in this paper the possible molecular mechanisms of microRNA-155 in inflammatory disorders. Furthermore, we also consider the feasibility of targeting it as a bright alternative to improve the early diagnose statistics and treatments in those diseases. MicroRNA-155 features a novel breakthrough in fine-tuning inflammatory responses and, thereby, in treating a wide spectrum of diseases with inflammation as a common denominator.
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Metadaten
Titel
MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases
verfasst von
Wu Xiaoyan
Eva Maria Arriero Pais
Li Lan
Chen Jingrui
Miao Lin
Patrick Asare Fordjour
Fan Guanwei
Publikationsdatum
15.12.2016
Verlag
Springer US
Erschienen in
Inflammation / Ausgabe 2/2017
Print ISSN: 0360-3997
Elektronische ISSN: 1573-2576
DOI
https://doi.org/10.1007/s10753-016-0488-y

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