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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 9/2016

01.09.2016 | Basic and Applied Science (I Lewkowich, Section Editor)

MicroRNAs in Allergic Disease

verfasst von: Eishika Dissanayake, Yuzaburo Inoue

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 9/2016

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Abstract

Purpose of Review

MicroRNAs (miRNAs) are short, single-stranded, non-coding RNAs that are increasingly being recognized as important epigenetic regulators. They have been implicated in the pathogenesis of many diseases including cancer, cardiovascular diseases, connective tissue diseases, and neuromuscular disorders.

Recent Findings

A few miRNAs have already been recognized as a core set of miRNAs important in allergic inflammation. These include let-7, miR-21, miR-142, and miR-146.

Summary

This review aims to bring together some of the recent findings on how miRNAs regulate allergic inflammation with special focus on asthma, atopic dermatitis, allergic rhinitis, and eosinophilic esophagitis. We will also touch upon extracellular miRNAs and future perspective of this field of study.
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Metadaten
Titel
MicroRNAs in Allergic Disease
verfasst von
Eishika Dissanayake
Yuzaburo Inoue
Publikationsdatum
01.09.2016
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 9/2016
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-016-0648-z

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