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01.11.2010 | Case Report

Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin

verfasst von: Kei Ohnuma, Osamu Hosono, Tomoki Katayose, Noritada Yoshikawa, Hiroshi Kawasaki, Takeshi Fujii, Naoki Oyaizu, Hirotoshi Tanaka, Chikao Morimoto

Erschienen in: Rheumatology International | Ausgabe 12/2010

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Abstract

We report herein a case of microscopic polyangiitis (MPA), presenting onset with a spiking fever, liver/biliary dysfunction without jaundice and calf pain without elevation of serum creatine phosphokinase. During 1 month of careful examinations for initial diagnosis, the patient developed renal dysfunction and pulmonary hemorrhage. Based on the results of positive MPO-ANCA, renal and pulmonary involvements, the patient was diagnosed with MPA and treated with high-dose prednisolone and oral cyclophosphamide. Soon after initiation of the treatment, symptoms such as fever, calf pain, liver/biliary dysfunction and renal dysfunction disappeared with decrease of MPO-ANCA titer to the normal level.

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Titel: Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin
verfasst von: Kei Ohnuma
Osamu Hosono
Tomoki Katayose
Noritada Yoshikawa
Hiroshi Kawasaki
Takeshi Fujii
Naoki Oyaizu
Hirotoshi Tanaka
Chikao Morimoto
Publikationsdatum: 01.11.2010
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 12/2010
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-009-1121-2

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