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Obesity Surgery

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26.02.2024 | Original Contributions

Mid-Term Diabetes Remission Outcome in Patients with BMI ≤ 30 kg/m² Following Sleeve Gastrectomy

verfasst von: Jian Wang, Yuxiao Chu, Jian Hong, Xiaocheng Zhu, Jason Widjaja, Libin Yao

Erschienen in: Obesity Surgery | Ausgabe 5/2024

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Abstract

Background

Bariatric and metabolic surgery is recommended for Asian patients with type 2 diabetes mellitus (T2DM) and BMI ≥ 27.5 kg/m². However, mid to long-term ·evidence is still lacking.

Methods

Patients’ data that underwent laparoscopic sleeve gastrectomy (SG) as the primary surgery at the Affiliated Hospital of Xuzhou Medical University were analyzed. Patients with T2DM diagnosed with either fasting blood glucose (FBG) ≥ 7.0 mmol/L or glycosylated hemoglobin (HbA1c) level ≥ 7.0% and 27.5 ≤ BMI ≤ 30 kg/m² were included.

Results

24 patients (7 male and 17 female) were included in this study. With a mean follow-up duration of 4.5 ± 1.1 years, the mean percentage of total weight loss (%TWL) was 14.4 ± 6.7%. Postoperatively, nine patients (37%) still required oral anti-diabetic medications, while no patients used insulin. FBG and HbA1c levels declined to 6.3 ± 1.5 mmol/L and 6.0 ± 1.0%, respectively. Fifteen patients (63%) were with HbA1c levels < 7% and without medication requirements, five patients (21%) were with HbA1c levels < 7% with the help of oral anti-diabetic medication, and four patients (16%) were with HbA1c levels > 7% with the help of oral anti-diabetic medication.

Conclusions

Our study provides further evidence that SG could result in both T2DM improvement and remission in patients with BMI ≤ 30 kg/m². Longer follow-up duration and larger sample will be needed in the future.

Graphical Abstract

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Titel: Mid-Term Diabetes Remission Outcome in Patients with BMI ≤ 30 kg/m2 Following Sleeve Gastrectomy
verfasst von: Jian Wang
Yuxiao Chu
Jian Hong
Xiaocheng Zhu
Jason Widjaja
Libin Yao
Publikationsdatum: 26.02.2024
Verlag: Springer US
Erschienen in: Obesity Surgery / Ausgabe 5/2024
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-024-07112-9

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Mid-Term Diabetes Remission Outcome in Patients with BMI ≤ 30 kg/m² Following Sleeve Gastrectomy