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Neurological Sciences

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01.04.2020 | Review Article

Mini review–vanadium-induced neurotoxicity and possible targets

verfasst von: Madhuri Ramji Jaiswal, Pravin Popatrao Kale

Erschienen in: Neurological Sciences | Ausgabe 4/2020

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Abstract

Vanadium, a transition metal, ubiquitous in nature is known to have therapeutic effect as well as toxic effect. It is known to possess antidiabetic, antitumor and antiparasitic activity. However, on long term exposure, it produces neurotoxicity which may result in memory impairment. The possible mechanism known to cause neurotoxicity suggested is oxidative stress and inflammation of neuronal cells. The present review has focused on discussing the role of protein P38 mitogen-activated protein kinase and oxidative stress as possible targets to treat vanadium-induced neurotoxicity.

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Titel: Mini review–vanadium-induced neurotoxicity and possible targets
verfasst von: Madhuri Ramji Jaiswal
Pravin Popatrao Kale
Publikationsdatum: 01.04.2020
Verlag: Springer International Publishing
Erschienen in: Neurological Sciences / Ausgabe 4/2020
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-04188-5

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