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13.07.2017 | Brief Report

Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay

verfasst von: Yu Pang, Jie Lu, Biyi Su, Huiwen Zheng, Yanlin Zhao

Erschienen in: Infection | Ausgabe 5/2017

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Abstract

Out of 12 nontuberculous mycobacteria (NTM) species, 5 were identified as Mycobacterium tuberculosis (MTB) by GeneXpert at a bacterial load of 10⁶. Notably, two species, including M. abscessus and M. smegmatis, were flagged as RIF-resistant MTB due to the high C(t) value of Probe E. In conclusion, our data have demonstrated that the misdiagnosis of MTB by GeneXpert assay is observed in five NTM species at a high bacterial load.

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Titel: Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay
verfasst von: Yu Pang
Jie Lu
Biyi Su
Huiwen Zheng
Yanlin Zhao
Publikationsdatum: 13.07.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Infection / Ausgabe 5/2017
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-017-1044-x

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Misdiagnosis of tuberculosis associated with some species of nontuberculous mycobacteria by GeneXpert MTB/RIF assay

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