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Journal of Cardiovascular Translational Research

10.06.2024 | Review

Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression

verfasst von: Li-Hua Yu, Ge-Lin Zhang

Erschienen in: Journal of Cardiovascular Translational Research

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Abstract

Recent research shows exercise is good for heart health, emphasizing the importance of physical activity. Sedentary behavior increases the risk of cardiovascular disease, while exercise can help prevent and treat it. Additionally, physical exercise can modulate the expression of lncRNAs, influencing cardiovascular disease progression. Therefore, understanding this relationship could help identify prospective biomarkers and therapeutic targets pertaining to cardiovascular ailments. This review has underscored recent advancements concerning the potential biomarkers of lncRNAs in cardiovascular diseases, while also summarizing existing knowledge regarding dysregulated lncRNAs and their plausible molecular mechanisms. Additionally, we have contributed novel perspectives on the underlying mechanisms of lncRNAs, which hold promise as potential biomarkers and therapeutic targets for cardiovascular conditions. The knowledge imparted in this review may prove valuable in guiding the design of future investigations and furthering the understanding of lncRNAs as diagnostic, prognostic, and therapeutic biomarkers for cardiovascular diseases.

Graphical Abstract

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Metadaten
Titel
Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression
verfasst von
Li-Hua Yu
Ge-Lin Zhang
Publikationsdatum
10.06.2024
Verlag
Springer US
Erschienen in
Journal of Cardiovascular Translational Research
Print ISSN: 1937-5387
Elektronische ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-024-10530-w

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