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Zeitschrift

Molecular Cancer

Molecular Cancer 1/2012

Ausgabe 1/2012

Inhaltsverzeichnis ( 91 Artikel )

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells

Amanda B Hummon, Jason J Pitt, Jordi Camps, Georg Emons, Susan B Skube, Konrad Huppi, Tamara L Jones, Tim Beissbarth, Frank Kramer, Marian Grade, Michael J Difilippantonio, Thomas Ried, Natasha J Caplen

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

Peter Barta, Carolyn Van Pelt, Taoyan Men, Burton F Dickey, Reuben Lotan, Seyed Javad Moghaddam

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

Aaron M Marshall, Rebecca J McClaine, Devikala Gurusamy, Jerilyn K Gray, Kara E Lewnard, Sohaib A Khan, Susan E Waltz

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene

Maria Meehan, Laavanya Parthasarathi, Niamh Moran, Caroline A Jefferies, Niamh Foley, Elisa Lazzari, Derek Murphy, Jacqueline Ryan, Berenice Ortiz, Armida W M Fabius, Timothy A Chan, Raymond L Stallings

01.12.2012 | Review | Ausgabe 1/2012 Open Access

Wnt signaling pathways in urological cancers: past decades and still growing

Shahana Majid, Sharanjot Saini, Rajvir Dahiya

01.12.2012 | Research | Ausgabe 1/2012 Open Access

miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer

Katarzyna Augoff, Brian McCue, Edward F Plow, Khalid Sossey-Alaoui

01.12.2012 | Research | Ausgabe 1/2012 Open Access

miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death

Adam Bryant, Catalina A Palma, Vivek Jayaswal, Yee Wa Yang, Mark Lutherborrow, David DF Ma

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Effect of cancer-associated mutations in the PlexinB1 gene

Chun Zhou, Oscar Gee-Wan Wong, John R Masters, Magali Williamson

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion

Qian Wu, Rajiv Dhir, Alan Wells

01.12.2012 | Research | Ausgabe 1/2012 Open Access

MutS homologue hMSH5: role in cisplatin-induced DNA damage response

Joshua D Tompkins, Xiling Wu, Chengtao Her

01.12.2012 | Research | Ausgabe 1/2012 Open Access

A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line

Inès Souissi, Patrick Ladam, Jean AH Cognet, Stéphanie Le Coquil, Nadine Varin-Blank, Fanny Baran-Marszak, Valeri Metelev, Remi Fagard

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

Elisa Latorre, Toma Tebaldi, Gabriella Viero, Antonino Maria Spartà, Alessandro Quattrone, Alessandro Provenzani

01.12.2012 | Research | Ausgabe 1/2012 Open Access

c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

Lucia Knopfová, Petr Beneš, Lucie Pekarčíková, Markéta Hermanová, Michal Masařík, Zuzana Pernicová, Karel Souček, Jan Šmarda

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

Zhongqiu Wang, Erich M Sturgis, Fenghua Zhang, Dapeng Lei, Zhensheng Liu, Li Xu, Xicheng Song, Qingyi Wei, Guojun Li

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Loss of HLTF function promotes intestinal carcinogenesis

Sumit Sandhu, Xiaoli Wu, Zinnatun Nabi, Mojgan Rastegar, Sam Kung, Sabine Mai, Hao Ding

01.12.2012 | Research | Ausgabe 1/2012 Open Access

IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors

Ivonne Regel, Melanie Eichenmüller, Saskia Joppien, Johanna Liebl, Beate Häberle, Josef Müller-Höcker, Angelika Vollmar, Dietrich von Schweinitz, Roland Kappler

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival

Chad R Schultz, William A Golembieski, Daniel A King, Stephen L Brown, Chaya Brodie, Sandra A Rempel

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

Tiago De Oliveira, Ivane Abiatari, Susanne Raulefs, Danguole Sauliunaite, Mert Erkan, Bo Kong, Helmut Friess, Christoph W Michalski, Jörg Kleeff

01.12.2012 | Research | Ausgabe 1/2012 Open Access

MicroRNA-143 Targets MACC1 to Inhibit Cell Invasion and Migration in Colorectal cancer

Yu Zhang, Zhongqiu Wang, Min Chen, Liang Peng, Xinying Wang, Qunying Ma, Fengli Ma, Bo Jiang

01.12.2012 | Research | Ausgabe 1/2012 Open Access

RhoA: A therapeutic target for chronic myeloid leukemia

Poonam R Molli, Madhura B Pradhan, Suresh H Advani, Nishigandha R Naik

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma

Weijie Poh, Winnie Wong, Huimin Ong, Myat Oo Aung, Seng Gee Lim, Boon Tin Chua, Han Kiat Ho

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells

Manish Tandon, Karthiga Gokul, Syed A Ali, Zujian Chen, Jane Lian, Gary S Stein, Jitesh Pratap

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation

Samantha M Zunich, Maria Valdovinos, Taneka Douglas, David Walterhouse, Philip Iannaccone, Marilyn L G Lamm

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion

L Gerard Toussaint III, Allan E Nilson, Jennie M Goble, Karla V Ballman, C David James, Florence Lefranc, Robert Kiss, Joon H Uhm

01.12.2012 | Research | Ausgabe 1/2012 Open Access

The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth

Sofia Bellou, Evdoxia Karali, Eleni Bagli, Nawaf Al-Maharik, Lucia Morbidelli, Marina Ziche, Herman Adlercreutz, Carol Murphy, Theodore Fotsis

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma

Cong-Jun Wang, Chao-Wen Xiao, Tian-Geng You, Ya-Xin Zheng, Wei Gao, Zhu-Qing Zhou, Jun Chen, Xin-Bo Xue, Jia Fan, Hui Zhang

01.12.2012 | Retraction Note | Ausgabe 1/2012 Open Access

Retraction Note: Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions

Ravi Mehrotra, Anurag Gupta, Mamta Singh, Rahela Ibrahim

01.12.2012 | Hypothesis | Ausgabe 1/2012 Open Access

A possible primary cause of cancer: deficient cellular interactions in endocrine pancreas

Maurice Israël

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection

Li Weng, Juan Du, Qinghui Zhou, Binbin Cheng, Jun Li, Denghai Zhang, Changquan Ling

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

Fiona O’Neill, Stephen F Madden, Sinead T Aherne, Martin Clynes, John Crown, Padraig Doolan, Robert O’Connor

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer

Ning Su, Liang Peng, Bingqing Xia, Yingying Zhao, Angao Xu, Jing Wang, Xinying Wang, Bo Jiang

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model

Toshiyuki Tsunoda, Takeharu Ota, Takahiro Fujimoto, Keiko Doi, Yoko Tanaka, Yasuhiro Yoshida, Masahiro Ogawa, Hiroshi Matsuzaki, Masato Hamabashiri, Darren R Tyson, Masahide Kuroki, Shingo Miyamoto, Senji Shirasawa

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades

Sateesh Kunigal, Moorthy P Ponnusamy, Navneet Momi, Surinder K Batra, Srikumar P Chellappan

01.12.2012 | Research | Ausgabe 1/2012 Open Access

β3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells

David A Tumbarello, Jillian Temple, James D Brenton

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Targeting filamin A reduces K-RAS–induced lung adenocarcinomas and endothelial response to tumor growth in mice

Rajesh K Nallapalli, Mohamed X Ibrahim, Alex X Zhou, Sashidar Bandaru, Sai Naresh Sunkara, Björn Redfors, David Pazooki, Yin Zhang, Jan Borén, Yihai Cao, Martin O Bergo, Levent M Akyürek

01.12.2012 | Review | Ausgabe 1/2012 Open Access

The emerging role of histone lysine demethylases in prostate cancer

Francesco Crea, Lei Sun, Antonello Mai, Yan Ting Chiang, William L Farrar, Romano Danesi, Cheryl D Helgason

01.12.2012 | Short communication | Ausgabe 1/2012 Open Access

IRF5 promotes the proliferation of human thyroid cancer cells

Michele Massimino, Paolo Vigneri, Manuela Fallica, Annamaria Fidilio, Alessandra Aloisi, Francesco Frasca, Livia Manzella

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines

Erika von Euw, Mohammad Atefi, Narsis Attar, Connie Chu, Sybil Zachariah, Barry L Burgess, Stephen Mok, Charles Ng, Deborah JL Wong, Bartosz Chmielowski, David I Lichter, Richard C Koya, Tara A McCannel, Elena Izmailova, Antoni Ribas

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

Liron Zehavi, Roi Avraham, Aviv Barzilai, Dalia Bar-Ilan, Roy Navon, Yechezkel Sidi, Dror Avni, Raya Leibowitz-Amit

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

Mingzhen Yang, Fang Yuan, Peng Li, Zhongjiao Chen, An Chen, Shuhui Li, Chuanmin Hu

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Cisplatin and ultra-violet-C synergistically down-regulate receptor tyrosine kinases in human colorectal cancer cells

Junji Kawaguchi, Seiji Adachi, Ichiro Yasuda, Takahiro Yamauchi, Masanori Nakashima, Tomohiko Ohno, Masahito Shimizu, Takashi Yoshioka, Masahiko Itani, Osamu Kozawa, Hisataka Moriwaki

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin

Céline Jacquemont, Julian A Simon, Alan D D'Andrea, Toshiyasu Taniguchi

01.12.2012 | Research | Ausgabe 1/2012 Open Access

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer

Felicitas Schmid, Susen Burock, Konrad Klockmeier, Peter M Schlag, Ulrike Stein

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation

Balazs Radnai, Csenge Antus, Boglarka Racz, Peter Engelmann, Janos Krisztian Priber, Zsuzsanna Tucsek, Balazs Veres, Zsuzsanna Turi, Tamas Lorand, Balazs Sumegi, Ferenc Gallyas Jr

01.12.2012 | Short communication | Ausgabe 1/2012 Open Access

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1

Louise van der Weyden, Mark J Arends, Alistair G Rust, George Poulogiannis, Rebecca E McIntyre, David J Adams

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

Fei Fei, Min Lim, Sabine Schmidhuber, Jürgen Moll, John Groffen, Nora Heisterkamp

01.12.2012 | Research | Ausgabe 1/2012 Open Access

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

Anna Djos, Tommy Martinsson, Per Kogner, Helena Carén

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Silencing of Apoptosis-Inducing factor and poly (ADP-ribose) glycohydrolase reveals novel roles in breast cancer cell death after chemotherapy

Xiaoxing Feng, Yiran Zhou, Alicia M Proctor, Mandi M Hopkins, Mengwei Liu, David W Koh

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Dichotomy effects of Akt signaling in breast cancer

Zhengang Peng, Jennifer Chao Weber, Zhaosheng Han, Rulong Shen, Wenchao Zhou, James R Scott, Michael WY Chan, Huey-Jen L Lin

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Role of toll-like receptor 4 on the immune escape of human oral squamous cell carcinoma and resistance of cisplatin-induced apoptosis

Zujun Sun, Qingqiong Luo, Dongxia Ye, Wantao Chen, Fuxiang Chen

01.12.2012 | Research | Ausgabe 1/2012 Open Access

MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma

Sheng-Dong Huang, Yang Yuan, Chong-Wen Zhuang, Bai-Ling Li, De-Jun Gong, Shu-Gang Wang, Zhi-Yong Zeng, He-Zhong Cheng

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

Hasan Zalzali, Mohamad Harajly, Lina Abdul-Latif, Nader El-Chaar, Ghassan Dbaibo, Stephen X Skapek, Raya Saab

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits

Ritu Jaiswal, Frederick Luk, Joyce Gong, Jean-Marie Mathys, Georges Emile Raymond Grau, Mary Bebawy

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer

Daniel J Freeman, Kevin McDorman, Selam Ogbagabriel, Carl Kozlosky, Bing-Bing Yang, Sameer Doshi, Juan Jose Perez-Ruxio, William Fanslow, Charlie Starnes, Robert Radinsky

01.12.2012 | Research | Ausgabe 1/2012 Open Access

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

Sandeep Singh, Jose Trevino, Namrata Bora-Singhal, Domenico Coppola, Eric Haura, Soner Altiok, Srikumar P Chellappan

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells

Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, Koji Kawakami

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells

Bettina Grismayer, Susanne Sölch, Bastian Seubert, Thomas Kirchner, Sonja Schäfer, Gustavo Baretton, Manfred Schmitt, Thomas Luther, Achim Krüger, Matthias Kotzsch, Viktor Magdolen

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Integrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis

Aditi Gupta, Wei Cao, Meenakshi A Chellaiah

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Hypoxia and estrogen are functionally equivalent in breast cancer-endothelial cell interdependence

Andrea L George, Shilpi Rajoria, Robert Suriano, Abraham Mittleman, Raj K Tiwari

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells

Aitziber Buqué, Jangi Sh Muhialdin, Alberto Muñoz, Begoña Calvo, Sergio Carrera, Unai Aresti, Aintzane Sancho, Itziar Rubio, Guillermo López-Vivanco

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non–small-cell lung cancer xenograft models

Angela Coxon, Beth Ziegler, Stephen Kaufman, Man Xu, Hongyu Wang, Dawn Weishuhn, Joanna Schmidt, Heather Sweet, Charlie Starnes, Douglas Saffran, Anthony Polverino

01.12.2012 | Research | Ausgabe 1/2012 Open Access

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer

Stephanie Geisler Crone, Anders Jacobsen, Birgitte Federspiel, Linda Bardram, Anders Krogh, Anders H Lund, Lennart Friis-Hansen

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis

Sarina Cameron, Lilia Merida de Long, Mehlika Hazar-Rethinam, Eleni Topkas, Liliana Endo-Munoz, Andrew Cumming, Orla Gannon, Alexander Guminski, Nicholas Saunders

01.12.2012 | Research | Ausgabe 1/2012 Open Access

The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas

Chitralekha Bhattacharya, Xiaolei Wang, Dorothea Becker

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Promoter Methylation status of HIN-1 associated with outcomes of ovarian clear cell adenocarcinoma

Chih-Ming Ho, Chi-Jung Huang, Chia-Yen Huang, Yih-Yiing Wu, Shwu-Fen Chang, Wen-Fang Cheng

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K

Gui Ren, Qifei Tian, Yanxin An, Bin Feng, Yuanyuan Lu, Jie Liang, Kai Li, Yulong Shang, Yongzhan Nie, Xin Wang, Daiming Fan

01.12.2012 | Research | Ausgabe 1/2012 Open Access

In non-transplant patients with multiple myeloma, the pre-treatment level of clonotypic cells predicts event-free survival

Kyle J Thulien, Andrew R Belch, Tony Reiman, Linda M Pilarski

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis

Nadzeya Goncharenko-Khaider, Isabelle Matte, Denis Lane, Claudine Rancourt, Alain Piché

01.12.2012 | Erratum | Ausgabe 1/2012 Open Access

Erratum to: Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer

Ning Su, Liang Peng, Bingqing Xia, Yingying Zhao, Angao Xu, Jing Wang, Xinying Wang, Bo Jiang

01.12.2012 | Research | Ausgabe 1/2012 Open Access

IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation

Yijing Li, Lei Wang, Loretta Pappan, Amy Galliher-Beckley, Jishu Shi

01.12.2012 | Research | Ausgabe 1/2012 Open Access

The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia

Xiaolu Zhang, Jiping Zeng, Minran Zhou, Bingnan Li, Yuanyuan Zhang, Tao Huang, Lixiang Wang, Jihui Jia, Chunyan Chen

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium

Stefanie Aust, Anna Bachmayr-Heyda, Petra Pateisky, Dan Tong, Silvia Darb-Esfahani, Carsten Denkert, Radoslav Chekerov, Jalid Sehouli, Sven Mahner, Toon Van Gorp, Ignace Vergote, Paul Speiser, Reinhard Horvat, Robert Zeillinger, Dietmar Pils

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

Laura D Nelson, Christian Bender, Heiko Mannsperger, Daniel Buergy, Patryk Kambakamba, Giridhar Mudduluru, Ulrike Korf, Dennis Hughes, Michael W Van Dyke, Heike Allgayer

01.12.2012 | Short communication | Ausgabe 1/2012 Open Access

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia

Jianbiao Zhou, Lip-Lee Cheong, Shaw-Cheng Liu, Phyllis SY Chong, Sylvia Mahara, Chonglei Bi, Kelly OK Ong, Qi Zeng, Wee Joo Chng

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Importance of glycolysis and oxidative phosphorylation in advanced melanoma

Jonhan Ho, Michelle Barbi de Moura, Yan Lin, Garret Vincent, Stephen Thorne, Lyn M Duncan, Lin Hui-Min, John M Kirkwood, Dorothea Becker, Bennett Van Houten, Stergios J Moschos

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Epidermal growth factor (EGF) and interleukin (IL)-1β synergistically promote ERK1/2-mediated invasive breast ductal cancer cell migration and invasion

Liqiang Ma, Fenghua Lan, Zhiyong Zheng, Feilai Xie, Lie Wang, Wei Liu, Junyong Han, Feng Zheng, Yanchuan Xie, Qiaojia Huang

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Highly efficient site-specific transgenesis in cancer cell lines

Iacovos P Michael, Claudio Monetti, Anthony C Chiu, Puzheng Zhang, Takeshi Baba, Koichiro Nishino, Siamak Agha-Mohammadi, Knut Woltjen, Hoon-Ki Sung, Andras Nagy

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Cooperative interaction of MUC1 with the HGF/c-Met pathway during hepatocarcinogenesis

Giray Bozkaya, Peyda Korhan, Murat Çokaklı, Esra Erdal, Özgül Sağol, Sedat Karademir, Christopher Korch, Neşe Atabey

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Characteristics of CD44 alternative splice pattern in the course of human colorectal adenocarcinoma progression

Balázs Bánky, Lívia Rásó-Barnett, Tamás Barbai, József Tímár, Péter Becságh, Erzsébet Rásó

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth

Sucheta Telang, Kristin K Nelson, Deanna L Siow, Abdullah Yalcin, Joshua M Thornburg, Yoannis Imbert-Fernandez, Alden C Klarer, Hanan Farghaly, Brian F Clem, John W Eaton, Jason Chesney

01.12.2012 | Research | Ausgabe 1/2012 Open Access

In vivo gene transfer targeting in pancreatic adenocarcinoma with cell surface antigens

Marie Lafitte, Benoit Rousseau, Isabelle Moranvillier, Miguel Taillepierre, Evelyne Peuchant, Véronique Guyonnet-Dupérat, Aurélie Bedel, Pierre Dubus, Hubert de Verneuil, François Moreau-Gaudry, Sandrine Dabernat

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells

Nicole Grabinski, Florian Ewald, Bianca T Hofmann, Katharina Staufer, Udo Schumacher, Björn Nashan, Manfred Jücker

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Genetic signatures shared in embryonic liver development and liver cancer define prognostically relevant subgroups in HCC

Diana Becker, Ioannis Sfakianakis, Markus Krupp, Frank Staib, Aslihan Gerhold-Ay, Anja Victor, Harald Binder, Maria Blettner, Thorsten Maass, Snorri Thorgeirsson, Peter R Galle, Andreas Teufel

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system

Zhen-Lin Nie, Yu-Qin Pan, Bang-Shun He, Ling Gu, Li-Ping Chen, Rui Li, Ye-Qiong Xu, Tian-Yi Gao, Guo-Qi Song, Andrew R Hoffman, Shu-Kui Wang, Ji-Fan Hu

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse

Shioko Kimura, Jorge Paiz, Mitsuhiro Yoneda, Taketomo Kido, Charles Vinson, Jerrold M Ward

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

Sara A Byron, David C Loch, Candice L Wellens, Andreas Wortmann, Jiayi Wu, John Wang, Kenichi Nomoto, Pamela M Pollock

01.12.2012 | Research | Ausgabe 1/2012 Open Access

The small GTPase RhoG mediates glioblastoma cell invasion

Aneta Kwiatkowska, Sebastien Didier, Shannon Fortin, Yayu Chuang, Timothy White, Michael E Berens, Elisabeth Rushing, Jennifer Eschbacher, Nhan L Tran, Amanda Chan, Marc Symons

01.12.2012 | Research | Ausgabe 1/2012 Open Access

P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines

Nitesh P Shirsath, Sonal M Manohar, Kalpana S Joshi

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Toru Furukawa, Etsuko Tanji, Yuko Kuboki, Takashi Hatori, Masakazu Yamamoto, Kyoko Shimizu, Noriyuki Shibata, Keiko Shiratori

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines

Andrea Cavazzoni, Roberta R Alfieri, Daniele Cretella, Francesca Saccani, Luca Ampollini, Maricla Galetti, Federico Quaini, Gallia Graiani, Denise Madeddu, Paola Mozzoni, Elena Galvani, Silvia La Monica, Mara Bonelli, Claudia Fumarola, Antonio Mutti, Paolo Carbognani, Marcello Tiseo, Elisabetta Barocelli, Pier Giorgio Petronini, Andrea Ardizzoni

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Regulation of colony stimulating factor-1 expression and ovarian cancer cell behavior in vitro by miR-128 and miR-152

Ho-Hyung Woo, Csaba F László, Stephen Greco, Setsuko K Chambers

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