Skip to main content
main-content

Zeitschrift

Molecular Cancer

Molecular Cancer 1/2013

Ausgabe 1/2013

Inhaltsverzeichnis ( 172 Artikel )

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Neel Sengupta, Christopher Yau, Anuratha Sakthianandeswaren, Dmitri Mouradov, Peter Gibbs, Nirosha Suraweera, Jean-Baptiste Cazier, Guadalupe Polanco-Echeverry, Anil Ghosh, Mohamed Thaha, Shafi Ahmed, Roger Feakins, David Propper, Sina Dorudi, Oliver Sieber, Andrew Silver, Cecilia Lai

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells

Adina Brett, Sony Pandey, Gail Fraizer

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

Charlotte M Smith, Volker Haucke, Adam McCluskey, Phillip J Robinson, Megan Chircop

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15)

Susana Lisboa, Nuno Cerveira, Susana Bizarro, Cecília Correia, Joana Vieira, Lurdes Torres, José M Mariz, Manuel R Teixeira

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats

Dolores C García-Olmo, María G Picazo, Inmaculada Toboso, Ana I Asensio, Damián García-Olmo

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

Yuanyuan Li, Syed M Meeran, Shweta N Patel, Huaping Chen, Tabitha M Hardy, Trygve O Tollefsbol

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type

Steven Rust, Sandrine Guillard, Kris Sachsenmeier, Carl Hay, Max Davidson, Anders Karlsson, Roger Karlsson, Erin Brand, David Lowne, John Elvin, Matt Flynn, Gene Kurosawa, Robert Hollingsworth, Lutz Jermutus, Ralph Minter

01.12.2013 | Reviewer acknowledgement | Ausgabe 1/2013 Open Access

Thanking our peer reviewers

Alan Storey

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

Tibor Görögh, László Bèress, Elgar S Quabius, Petra Ambrosch, Markus Hoffmann

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer

Rebekah L Zinn, Eric E Gardner, Irina Dobromilskaya, Sara Murphy, Luigi Marchionni, Christine L Hann, Charles M Rudin

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration

Liangping Yuan, Hongying Zhang, Jingbo Liu, Joshua B Rubin, Yoon-Jae Cho, Hui Kuo Shu, Matthew Schniederjan, Tobey J MacDonald

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion

Vanessa M Freitas, Jônatas Bussador do Amaral, Thaiomara A Silva, Emerson S Santos, Flávia R Mangone, João de Jesus Pinheiro, Ruy G Jaeger, Maria A Nagai, Gláucia Maria Machado-Santelli

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a

Chao Liang, Wei Chen, Xiao Zhi, Tao Ma, Xuefeng Xia, Hao Liu, Qi Zhang, Qida Hu, Yun Zhang, Xueli Bai, Tingbo Liang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

PTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alpha

Chunhua Yang, Shujing Li, Miao Wang, Alan K Chang, Ying Liu, Feng Zhao, Liyun Xiao, Lin Han, Dao Wang, Shen Li, Huijian Wu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site

Kurtis Eisermann, Carly J Broderick, Anton Bazarov, Mustafa M Moazam, Gail C Fraizer

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer

Robert S Hudson, Ming Yi, Natalia Volfovsky, Robyn L Prueitt, Dominic Esposito, Stefano Volinia, Chang-Gong Liu, Aaron J Schetter, Katrien Van Roosbroeck, Robert M Stephens, George A Calin, Carlo M Croce, Stefan Ambs

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1

Laura Creevey, Jacqueline Ryan, Harry Harvey, Isabella M Bray, Maria Meehan, Adnan R Khan, Raymond L Stallings

01.12.2013 | Research | Ausgabe 1/2013 Open Access

1H-NMR based metabonomic profiling of human esophageal cancer tissue

Liang Wang, Jie Chen, Longqi Chen, Pengchi Deng, Qian bu, Pu Xiang, Manli Li, Wenjie Lu, Youzhi Xu, Hongjun Lin, Tianming Wu, Huijuan Wang, Jing Hu, Xiaoni Shao, Xiaobo Cen, Ying-Lan Zhao

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Molecular features in arsenic-induced lung tumors

Roland Hubaux, Daiana D Becker-Santos, Katey SS Enfield, David Rowbotham, Stephen Lam, Wan L Lam, Victor D Martinez

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation

Mariana Toricelli, Fabiana HM Melo, Giovani B Peres, Débora CP Silva, Miriam G Jasiulionis

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction, and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells

David J Panka, Qingjun Liu, Andrew K Geissler, James W Mier

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms

Kerstin Maria Kampa-Schittenhelm, Michael Charles Heinrich, Figen Akmut, Hartmut Döhner, Konstanze Döhner, Marcus Matthias Schittenhelm

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Targeting the Vav3 oncogene enhances docetaxel-induced apoptosis through the inhibition of androgen receptor phosphorylation in LNCaP prostate cancer cells under chronic hypoxia

Takeo Nomura, Mutsushi Yamasaki, Kenichi Hirai, Toru Inoue, Ryuta Sato, Keiko Matsuura, Masatsugu Moriyama, Fuminori Sato, Hiromitsu Mimata

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Epidermal growth factor receptor variant type III markedly accelerates angiogenesis and tumor growth via inducing c-myc mediated angiopoietin-like 4 expression in malignant glioma

Yasufumi Katanasaka, Yasuo Kodera, Yuka Kitamura, Tatsuya Morimoto, Tomohide Tamura, Fumiaki Koizumi

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells

Karthik M. Kodigepalli, Pavana Anur, Paul Spellman, Peter J. Sims, Meera Nanjundan

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2

Mitsuhiro Matsuo, Chisato Nakada, Yoshiyuki Tsukamoto, Tsuyoshi Noguchi, Tomohisa Uchida, Naoki Hijiya, Keiko Matsuura, Masatsugu Moriyama

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Molecular changes induced by the curcumin analogue D6 in human melanoma cells

Carla Rozzo, Manuela Fanciulli, Cristina Fraumene, Antonio Corrias, Tiziana Cubeddu, Ilaria Sassu, Sara Cossu, Valentina Nieddu, Grazia Galleri, Emanuela Azara, Maria Antonietta Dettori, Davide Fabbri, Giuseppe Palmieri, Marina Pisano

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells

Weiyun Wu, Jingfang Yang, Xiao Feng, Hao Wang, Shicai Ye, Pengchun Yang, Wenkai Tan, Guoli Wei, Yu Zhou

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Gene expression profiling of chronic myeloid leukemia with variant t(9;22) reveals a different signature from cases with classic translocation

Francesco Albano, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Luciana Impera, Crescenzio Francesco Minervini, Angela Minervini, Antonella Russo Rossi, Giuseppina Tota, Paola Casieri, Giorgina Specchia

01.12.2013 | Research | Ausgabe 1/2013 Open Access

RETRACTED ARTICLE: Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

Bethany Perez White, Mary Ellen Molloy, Huiping Zhao, Yiyun Zhang, Debra A. Tonetti

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells

Catherine A. Taylor, Qifa Zheng, Zhongda Liu, John E. Thompson

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Expression of HPV16 E5 down-modulates the TGFbeta signaling pathway

Deborah French, Francesca Belleudi, Maria Vittoria Mauro, Francesca Mazzetta, Salvatore Raffa, Vincenza Fabiano, Antonio Frega, Maria Rosaria Torrisi

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

Xing Lu, Swetha Parvathaneni, Toshifumi Hara, Ashish Lal, Sudha Sharma

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity

Melissa B Davis, Xinyu Liu, Shiyao Wang, Jaxk Reeves, Andrey Khramtsov, Dezheng Huo, Olufunmilayo I Olopade

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling

Michaela Lang, Melanie Borgmann, Georg Oberhuber, Rayko Evstatiev, Kristine Jimenez, Kyle W Dammann, Manuela Jambrich, Vineeta Khare, Christoph Campregher, Robin Ristl, Christoph Gasche

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein interactions with Bak

Xiaobo Cao, Jeremy L Yap, M Karen Newell-Rogers, Chander Peddaboina, Weihua Jiang, Harry T Papaconstantinou, Dan Jupitor, Arun Rai, Kwan-Young Jung, Richard P Tubin, Wenbo Yu, Kenno Vanommeslaeghe, Paul T Wilder, Alexander D MacKerell JR, Steven Fletcher, Roy W Smythe

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells

Alejandro García-Regalado, Miguel Vargas, Alejandro García-Carrancá, Elena Aréchaga-Ocampo, Claudia Haydée González-De la Rosa

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer

Natalie Ludyga, Sonja Englert, Kerstin Pflieger, Sandra Rauser, Herbert Braselmann, Axel Walch, Gert Auer, Heinz Höfler, Michaela Aubele

01.12.2013 | Research | Ausgabe 1/2013 Open Access

IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus

Miao-Fen Chen, Ping-Tsung Chen, Ming Shian Lu, Paul Yang Lin, Wen-Cheng Chen, Kuan-Der Lee

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

Khalid Abubaker, Ardian Latifi, Rod Luwor, Simon Nazaretian, Hongjian Zhu, Michael A Quinn, Erik W Thompson, Jock K Findlay, Nuzhat Ahmed

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line

Vincenzo Pagliarulo, Patrizia Ancona, Mauro Niso, Nicola Antonio Colabufo, Marialessandra Contino, Luigi Cormio, Amalia Azzariti, Arcangelo Pagliarulo

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The MicroRNA-148/152 Family: Multi-faceted Players

Yue Chen, Yong-Xi Song, Zhen-Ning Wang

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells

Uri Rozovski, George A Calin, Tetsuro Setoyama, Lucilla D’Abundo, David M Harris, Ping Li, Zhiming Liu, Srdana Grgurevic, Alessandra Ferrajoli, Stefan Faderl, Jan A Burger, Susan O’Brien, William G Wierda, Michael J Keating, Zeev Estrov

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Iodine and doxorubicin, a good combination for mammary cancer treatment: antineoplastic adjuvancy, chemoresistance inhibition, and cardioprotection

Yunuen Alfaro, Guadalupe Delgado, Alfonso Cárabez, Brenda Anguiano, Carmen Aceves

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Raman imaging at biological interfaces: applications in breast cancer diagnosis

Jakub Surmacki, Jacek Musial, Radzislaw Kordek, Halina Abramczyk

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

Sitai Liang, Gabriela Cuevas, Shaza Tizani, Tiffanie Salas, Huijuan Liu, Baojie Li, Samy L Habib

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis

Tao Ji, Carol Lin, Lauren S Krill, Ramez Eskander, Yi Guo, Xiaolin Zi, Bang H Hoang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repair

Yen-Lin Chu, Xiling Wu, Yang Xu, Chengtao Her

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove

Abul Azad, Alan Storey

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemia

Kerstin Maria Kampa-Schittenhelm, Michael Charles Heinrich, Figen Akmut, Katharina Henriette Rasp, Barbara Illing, Hartmut Döhner, Konstanze Döhner, Marcus Matthias Schittenhelm

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Global profiling of prolactin-modulated transcripts in breast cancer in vivo

Takahiro Sato, Thai H Tran, Amy R Peck, Chengbao Liu, Adam Ertel, Justin Lin, Lynn M Neilson, Hallgeir Rui

01.12.2013 | Research | Ausgabe 1/2013 Open Access

6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

Rodica P Bunaciu, Andrew Yen

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Role of SIRT3 in the regulation of redox balance during oral carcinogenesis

I-Chieh Chen, Wei-Fan Chiang, Shyun-Yeu Liu, Pei-Fen Chen, Hung-Che Chiang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN

Pankaj Sharma, Ashley Evans Knowell, Swathi Chinaranagari, Shravan Komaragiri, Peri Nagappan, Divya Patel, Mathew C Havrda, Jaideep Chaudhary

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Novel microRNA-based assay demonstrates 92% agreement with diagnosis based on clinicopathologic and management data in a cohort of patients with carcinoma of unknown primary

George Pentheroudakis, Nicholas Pavlidis, George Fountzilas, Dimitrios Krikelis, Anna Goussia, Aikaterini Stoyianni, Mats Sanden, Brianna St Cyr, Noga Yerushalmi, Hila Benjamin, Eti Meiri, Ayelet Chajut, Shai Rosenwald, Ranit Aharonov, Yael Spector

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Pseudomonas aeruginosa NfsB and nitro-CBI-DEI – a promising enzyme/prodrug combination for gene directed enzyme prodrug therapy

Laura K Green, Sophie P Syddall, Kendall M Carlin, Glenn D Bell, Christopher P Guise, Alexandra M Mowday, Michael P Hay, Jeffrey B Smaill, Adam V Patterson, David F Ackerley

01.12.2013 | Research | Ausgabe 1/2013 Open Access

BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification

Ben-yuan Jiang, Xu-chao Zhang, Jian Su, Wei Meng, Xue-ning Yang, Jin-ji Yang, Qing Zhou, Zhi-yong Chen, Zhi-hong Chen, Zhi Xie, Shi-liang Chen, Yi-long Wu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers

Tsutomu Oshima, Shuji Sato, Junichi Kato, Yuki Ito, Takahiro Watanabe, Isamu Tsuji, Akira Hori, Tomofumi Kurokawa, Toshio Kokubo

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Regulation of protumorigenic pathways by Insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis

Priyanka Sehgal, Neeraj Kumar, Varuvar Rajesh Praveen Kumar, Shilpa Patil, Animesh Bhattacharya, Manavalan Vijaya Kumar, Geetashree Mukherjee, Paturu Kondaiah

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

Wen Zhou, Xiangling Feng, Caiping Ren, Xingjun Jiang, Weidong Liu, Wei Huang, Zhihong Liu, Zan Li, Liang Zeng, Lei Wang, Bin Zhu, Jia Shi, Jie Liu, Chang Zhang, Yanyu Liu, Kaitai Yao

01.12.2013 | Research | Ausgabe 1/2013 Open Access

EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth

Agnieszka Martowicz, Johannes Rainer, Julien Lelong, Gilbert Spizzo, Guenther Gastl, Gerold Untergasser

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Biochemical and biological characterization of exosomes containing prominin-1/CD133

Germana Rappa, Javier Mercapide, Fabio Anzanello, Robert M Pope, Aurelio Lorico

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner

Jianjun Lei, Jiguang Ma, Qingyong Ma, Xuqi Li, Han Liu, Qinhong Xu, Wanxing Duan, Qing Sun, Jun Xu, Zheng Wu, Erxi Wu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Orthotopic transplantation of retinoblastoma cells into vitreous cavity of zebrafish for screening of anticancer drugs

Dong Hyun Jo, Dain Son, Yirang Na, Manyoung Jang, Jae-Hoon Choi, Jin Hyoung Kim, Young Suk Yu, Seung Hyeok Seok, Jeong Hun Kim

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

Mohd Askandar Iqbal, Farid Ahmad Siddiqui, Vibhor Gupta, Shilpi Chattopadhyay, Prakasam Gopinath, Bhupender Kumar, Siddharth Manvati, Noor Chaman, Rameshwar NK Bamezai

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

The evolution of malignant and reactive γδ + T cell clones in a relapse T-ALL case after allogeneic stem cell transplantation

Shaohua Chen, Xin Huang, Haitao Zheng, Suxia Geng, Xiuli Wu, Lijian Yang, Jianyu Weng, Xin Du, Yangqiu Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme

Leroi V DeSouza, Ajay Matta, Zia Karim, Joydeep Mukherjee, X Simon Wang, Olga Krakovska, Gelareh Zadeh, Abhijit Guha, KW Michael Siu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5

Christelle P El-Haibi, Praveen Sharma, Rajesh Singh, Pranav Gupta, Dennis D Taub, Shailesh Singh, James W Lillard, Jr

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

Laetitia Moreno Y Banuls, Adriana Katz, Walter Miklos, Alessio Cimmino, Daniel M. Tal, Elena Ainbinder, Martin Zehl, Ernst Urban, Antonio Evidente, Brigitte Kopp, Walter Berger, Olivier Feron, Steven Karlish, Robert Kiss

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A gene expression profile indicative of early stage HER2 targeted therapy response

Fiona O’Neill, Stephen F Madden, Martin Clynes, John Crown, Padraig Doolan, Sinéad T Aherne, Robert O’Connor

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells

Parnetta Sutton, Jeffrey A Borgia, Philip Bonomi, Janet MD Plate

01.12.2013 | Research | Ausgabe 1/2013 Open Access

TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells

Daniel S Straus

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma

Lei Jin, Erich M Sturgis, Yang Zhang, Zhigang Huang, Xicheng Song, Chao Li, Qingyi Wei, Guojun Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

miR-99b-targeted mTOR induction contributes to irradiation resistance in pancreatic cancer

Feng Wei, Yan Liu, Yanhai Guo, An Xiang, Guangyi Wang, Xiaochang Xue, Zifan Lu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

TMEM16A alternative splicing coordination in breast cancer

Ifeoma Ubby, Erica Bussani, Antonio Colonna, Giuseppe Stacul, Martina Locatelli, Paolo Scudieri, Luis Galietta, Franco Pagani

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase

Yuli Lin, Nana Peng, Jianping Li, Hongqin Zhuang, Zi-Chun Hua

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Late developing mammary tumors and hyperplasia induced by a low-oncogenic variant of mouse mammary tumor virus (MMTV) express genes identical to those induced by canonical MMTV

Robert D Bruno, Sonia M Rosenfield, Gilbert H Smith

01.12.2013 | Research | Ausgabe 1/2013 Open Access

FGFR3 has tumor suppressor properties in cells with epithelial phenotype

Marie Lafitte, Isabelle Moranvillier, Stéphane Garcia, Evelyne Peuchant, Juan Iovanna, Benoit Rousseau, Pierre Dubus, Véronique Guyonnet-Dupérat, Geneviève Belleannée, Jeanne Ramos, Aurélie Bedel, Hubert de Verneuil, François Moreau-Gaudry, Sandrine Dabernat

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The complexity of NF-κB signaling in inflammation and cancer

Bastian Hoesel, Johannes A Schmid

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The regulation of toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells

Haiyan Guo, Ying Chen, Xiaobo Hu, Guanxiang Qian, Shengfang Ge, Jianjun Zhang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Cigarette smoke induces epithelial to mesenchymal transition and increases the metastatic ability of breast cancer cells

Francescopaolo Di Cello, V Lynn Flowers, Huili Li, Briana Vecchio-Pagán, Brent Gordon, Kirsten Harbom, James Shin, Robert Beaty, Wei Wang, Cory Brayton, Stephen B Baylin, Cynthia A Zahnow

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Epigenetic silencing of RASSF1A deregulates cytoskeleton and promotes malignant behavior of adrenocortical carcinoma

Reju Korah, James M Healy, John W Kunstman, Annabelle L Fonseca, Amir H Ameri, Manju L Prasad, Tobias Carling

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts

Enas A El-Karim, Engda G Hagos, Amr M Ghaleb, Bing Yu, Vincent W Yang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Characterization and identification of PARM-1 as a new potential oncogene

Cyndia Charfi, Louis-Charles Levros Jr, Elsy Edouard, Eric Rassart

01.12.2013 | Review | Ausgabe 1/2013 Open Access

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

Iraia García-Santisteban, Godefridus J Peters, Elisa Giovannetti, Jose Antonio Rodríguez

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

Roberto Gomez-Casal, Chitralekha Bhattacharya, Nandita Ganesh, Lisa Bailey, Per Basse, Michael Gibson, Michael Epperly, Vera Levina

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells

Xin Yan, Hongwei Liang, Ting Deng, Kegan Zhu, Suyang Zhang, Nan Wang, Xueyuan Jiang, Xueliang Wang, Rui Liu, Ke Zen, Chen-Yu Zhang, Yi Ba, Xi Chen

01.12.2013 | Research | Ausgabe 1/2013 Open Access

PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling

M Katie Conley-LaComb, Allen Saliganan, Pridvi Kandagatla, Yong Q Chen, Michael L Cher, Sreenivasa R Chinni

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Fludarabine treatment favors the retention of miR-485-3p by prostate cancer cells: implications for survival

Serena Lucotti, Giuseppe Rainaldi, Monica Evangelista, Milena Rizzo

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Cancer risk in immune-mediated inflammatory diseases (IMID)

Rudi Beyaert, Laurent Beaugerie, Gert Van Assche, Lieve Brochez, Jean-Christophe Renauld, Manuelle Viguier, Veronique Cocquyt, Guy Jerusalem, Jean-Pascal Machiels, Hans Prenen, Pierre Masson, Edouard Louis, Filip De Keyser

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

Roberto Puzone, Graziana Savarino, Sandra Salvi, Maria Giovanna Dal Bello, Giulia Barletta, Carlo Genova, Erika Rijavec, Claudio Sini, Alessia Isabella Esposito, Giovanni Battista Ratto, Mauro Truini, Francesco Grossi, Ulrich Pfeffer

01.12.2013 | Research | Ausgabe 1/2013 Open Access

ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours

Annica Wilzén, Cecilia Krona, Baldur Sveinbjörnsson, Erik Kristiansson, Daniel Dalevi, Ingrid Øra, Katleen De Preter, Raymond L Stallings, John Maris, Rogier Versteeg, Staffan Nilsson, Per Kogner, Frida Abel

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses

Joanna Obacz, Silvia Pastorekova, Borek Vojtesek, Roman Hrstka

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

Simon Welner, Nicole Hartwig Trier, Morten Frisch, Henning Locht, Paul Robert Hansen, Gunnar Houen

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The complexity of bladder cancer: long noncoding RNAs are on the stage

Quanan Zhang, Mo Su, Guangming Lu, Jiangdong Wang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Oncolytic viruses as therapeutic cancer vaccines

David L Bartlett, Zuqiang Liu, Magesh Sathaiah, Roshni Ravindranathan, Zongbi Guo, Yukai He, Zong Sheng Guo

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines

Giampiero Porcu, Ainslie B Parsons, Daniele Di Giandomenico, Giuseppe Lucisano, Maria Giovanna Mosca, Charles Boone, Antonella Ragnini-Wilson

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling

Xin Zheng, Xiaohong Gai, Feihu Ding, Zhongtang Lu, Kangsheng Tu, Yingmin Yao, Qingguang Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer

Kolaparthi Venkatasubbarao, Lindsay Peterson, Shujie Zhao, Ping Hill, Lin Cao, Qing Zhou, Steffan T Nawrocki, James W Freeman

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds

Timur R Samatov, Alexander G Tonevitsky, Udo Schumacher

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Cancer: tilting at windmills?

Prakash Kulkarni, Takumi Shiraishi, Rahul V Kulkarni

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Expression profiling of ion channel genes predicts clinical outcome in breast cancer

Jae-Hong Ko, Eun A Ko, Wanjun Gu, Inja Lim, Hyoweon Bang, Tong Zhou

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells

He Li, Juan Wang, Huiyu Xu, Rui Xing, Yuanming Pan, Wenmei Li, Jiantao Cui, Hongbing Zhang, Youyong Lu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico

Cinzia Tesauro, Blasco Morozzo della Rocca, Alessio Ottaviani, Andrea Coletta, Laura Zuccaro, Barbara Arnò, Ilda D'Annessa, Paola Fiorani, Alessandro Desideri

01.12.2013 | Research | Ausgabe 1/2013 Open Access

miR-204 mediated loss of Myeloid cell leukemia-1 results in pancreatic cancer cell death

Zhiyu Chen, Veena Sangwan, Sulagna Banerjee, Tiffany Mackenzie, Vikas Dudeja, Xiaowu Li, Huaizhi Wang, Selwyn M Vickers, Ashok K Saluja

01.12.2013 | Letter to the Editor | Ausgabe 1/2013 Open Access

The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion

Jade Peres, Sharon Prince

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells

Soumik Agarwal, Karishma S Amin, Shankar Jagadeesh, Gokul Baishay, Paruchuri G Rao, Nabin C Barua, Samir Bhattacharya, Partha P Banerjee

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MTA2 promotes gastric cancer cells invasion and is transcriptionally regulated by Sp1

Chenfei Zhou, Jun Ji, Qu Cai, Min Shi, Xuehua Chen, Yingyan Yu, Bingya Liu, Zhenggang Zhu, Jun Zhang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposure

Kiriaki Panagopoulos, Sam Cross-Knorr, Christen Dillard, Dionysios Pantazatos, Michael Del Tatto, David Mills, Lisa Goldstein, Joseph Renzulli, Peter Quesenberry, Devasis Chatterjee

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma

Daniel Weissinger, Katrin E Tagscherer, Stephan Macher-Göppinger, Axel Haferkamp, Nina Wagener, Wilfried Roth

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Synthesis, characterization, and evaluation of a novel inhibitor of WNT/β-catenin signaling pathway

Zhao Yan, Zhongling Zhu, Jinghui Wang, Jian Sun, Yihui Chen, Guang Yang, Wenting Chen, Yuheng Deng

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma

Na Liu, Ning Jiang, Rui Guo, Wei Jiang, Qing-Mei He, Ya-Fei Xu, Ying-Qin Li, Ling-Long Tang, Yan-Ping Mao, Ying Sun, Jun Ma

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Astrocyte elevated gene-1 is associated with metastasis in head and neck squamous cell carcinoma through p65 phosphorylation and upregulation of MMP1

Yi-Ping Wang, I-Ju Liu, Chiung-Pin Chiang, Han-Chung Wu

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers

Iwona Ziółkowska-Suchanek, Maria Mosor, Małgorzata Wierzbicka, Małgorzata Rydzanicz, Marta Baranowska, Jerzy Nowak

01.12.2013 | Research | Ausgabe 1/2013 Open Access

MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma

Ning Wang, Meifen Zhu, Sai-Wah Tsao, Kwan Man, Zhangjin Zhang, Yibin Feng

01.12.2013 | Research | Ausgabe 1/2013 Open Access

CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1α/CXCR4 axis

Ai-Fang Huang, Min-Wei Chen, Shih-Ming Huang, Chu-Lien Kao, Hung-Cheng Lai, James Yi-Hsin Chan

01.12.2013 | Research | Ausgabe 1/2013 Open Access

¹H NMR-based metabolic profiling of human rectal cancer tissue

Huijuan Wang, Liang Wang, Hailong Zhang, Pengchi Deng, Jie Chen, Bin Zhou, Jing Hu, Jun Zou, Wenjie Lu, Pu Xiang, Tianming Wu, Xiaoni Shao, Yuan Li, Zongguang Zhou, Ying-Lan Zhao

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells

Jingcao Huang, Shuiliang Wang, Hui Lyu, Bo Cai, XiaoHe Yang, Jianxiang Wang, Bolin Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model

Urska Kamensek, Gregor Sersa, Maja Cemazar

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Expression analysis and in silico characterization of intronic long noncoding RNAs in renal cell carcinoma: emerging functional associations

Angela A Fachel, Ana C Tahira, Santiago A Vilella-Arias, Vinicius Maracaja-Coutinho, Etel RP Gimba, Giselle M Vignal, Franz S Campos, Eduardo M Reis, Sergio Verjovski-Almeida

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Ets-1 regulates intracellular glutathione levels: key target for resistant ovarian cancer

Meghan L Verschoor, Gurmit Singh

01.12.2013 | Research | Ausgabe 1/2013 Open Access

High mitochondria content is associated with prostate cancer disease progression

Katharina Grupp, Karolina Jedrzejewska, Maria Christina Tsourlakis, Christina Koop, Waldemar Wilczak, Meike Adam, Alexander Quaas, Guido Sauter, Ronald Simon, Jakob Robert Izbicki, Markus Graefen, Hartwig Huland, Thorsten Schlomm, Sarah Minner, Stefan Steurer

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway

Leticia Oliveira-Ferrer, Jasmin Wellbrock, Udo Bartsch, Eva Maria Murga Penas, Jessica Hauschild, Marianne Klokow, Carsten Bokemeyer, Walter Fiedler, Gunter Schuch

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition

Giada Gelsomino, Paola A Corsetto, Ivana Campia, Gigliola Montorfano, Joanna Kopecka, Barbara Castella, Elena Gazzano, Dario Ghigo, Angela M Rizzo, Chiara Riganti

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Proteomic analysis reveals heat shock protein 70 has a key role in polycythemia Vera

Miguel Gallardo, Santiago Barrio, Marisol Fernandez, Alberto Paradela, Alicia Arenas, Oscar Toldos, Rosa Ayala, Enriqueta Albizua, Ana Jimenez, Santiago Redondo, Rosa Maria Garcia-Martin, Florinda Gilsanz, Juan Pablo Albar, Joaquin Martinez-Lopez

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis

Hui Ren, Junghui Koo, Baoxiang Guan, Ping Yue, Xingming Deng, Mingwei Chen, Fadlo R Khuri, Shi-Yong Sun

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1

Xuelei Cao, Li Zhang, Yongyu Shi, Yue Sun, Shen Dai, Chun Guo, Faliang Zhu, Qun wang, Jianing Wang, Xiaoyan Wang, Youhai H Chen, Lining Zhang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis

Jiao Zheng, Min Yang, Jianghua Shao, Yanju Miao, Jiahuai Han, Jie Du

01.12.2013 | Research | Ausgabe 1/2013 Open Access

LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/stat3/akt pathway

Xuan Song, Jiabei Wang, Tongsen Zheng, Ruipeng Song, Yingjian Liang, Nishant Bhatta, Dalong Yin, Shangha Pan, Jiaren Liu, Hongchi Jiang, Lianxin Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway

Sarita Saraswati, Shakti Kumar, Abdulqader A Alhaider

01.12.2013 | Research | Ausgabe 1/2013 Open Access

6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α

Qun Liu, Yong-Bo Peng, Ping Zhou, Lian-Wen Qi, Mu Zhang, Ning Gao, E-Hu Liu, Ping Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway

Jian-Ye Liu, Dong Qian, Li-Ru He, Yong-Hong Li, Yi-Ji Liao, Shi-Juan Mai, Xiao-Peng Tian, Yan-Hui Liu, Jia-Xing Zhang, Hsiang-Fu Kung, Yi-Xin Zeng, Fang-Jian Zhou, Dan Xie

01.12.2013 | Research | Ausgabe 1/2013 Open Access

TGM3, a candidate tumor suppressor gene, contributes to human head and neck cancer

Xiangbing Wu, Wei Cao, Xu Wang, Jianjun Zhang, Zhongjing Lv, Xing Qin, Yadi Wu, Wantao Chen

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Tumor glycolysis as a target for cancer therapy: progress and prospects

Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind

01.12.2013 | Research | Ausgabe 1/2013 Open Access

DKK1 promotes hepatocellular carcinoma cell migration and invasion through β-catenin/MMP7 signaling pathway

Liang Chen, Ming Li, Qian Li, Chao-jie Wang, Song-qiang Xie

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir

Tim De Schutter, Graciela Andrei, Dimitri Topalis, Sophie Duraffour, Tania Mitera, Joost van den Oord, Patrick Matthys, Robert Snoeck

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The roles of FOXM1 in pancreatic stem cells and carcinogenesis

Ming Quan, Peipei Wang, Jiujie Cui, Yong Gao, Keping Xie

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Effects of miR-193a and sorafenib on hepatocellular carcinoma cells

Alessandro Salvi, Isabel Conde, Edoardo Abeni, Bruna Arici, Ilaria Grossi, Claudia Specchia, Nazario Portolani, Sergio Barlati, Giuseppina De Petro

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Mapping PAM4 (clivatuzumab), a monoclonal antibody in clinical trials for early detection and therapy of pancreatic ductal adenocarcinoma, to MUC5AC mucin

David V Gold, Guy Newsome, Donglin Liu, David M Goldenberg

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells

Sofia Winslow, Karin Leandersson, Christer Larsson

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres

Monica Patanè, Paola Porrati, Elisa Bottega, Sara Morosini, Gabriele Cantini, Vita Girgenti, Ambra Rizzo, Marica Eoli, Bianca Pollo, Francesca L Sciacca, Serena Pellegatta, Gaetano Finocchiaro

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Microrna-124 targets flotillin-1 to regulate proliferation and migration in breast cancer

Laisheng Li, Jinmei Luo, Bo Wang, Dong Wang, Xinhua Xie, Linjing Yuan, Jiaoli Guo, Shaoyan Xi, Jie Gao, Xiaoti Lin, Yanan Kong, Xiangdong Xu, Hailing Tang, Xiaoming Xie, Min Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness

Federica Brugnoli, Silvia Grassilli, Manuela Piazzi, Maria Palomba, Ervin Nika, Alberto Bavelloni, Silvano Capitani, Valeria Bertagnolo

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines

Wenyu Liu, Gajan Jeganathan, Sohrab Amiri, Katherine M Morgan, Bríd M Ryan, Sharon R Pine

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Id4 dependent acetylation restores mutant-p53 transcriptional activity

Ashley E Knowell, Divya Patel, Derrick J Morton, Pankaj Sharma, Shanora Glymph, Jaideep Chaudhary

01.12.2013 | Research | Ausgabe 1/2013 Open Access

miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression

Fang-Ting Duan, Feng Qian, Ke Fang, Kang-Yu Lin, Wen-Tao Wang, Yue-Qin Chen

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

Meiling Zhang, Jamie Truscott, Judith Davie

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Activation of cellular immunity and marked inhibition of liver cancer in a mouse model following gene therapy and tumor expression of GM-SCF, IL-21, and Rae-1

Mingrong Cheng, Kangkang Zhi, Xiaoyan Gao, Bing He, Yingchun Li, Jiang Han, Zhiping Zhang, Yan Wu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A TrkB–STAT3–miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells

Wei Bao, Hui-Hui Wang, Fu-Ju Tian, Xiao-Ying He, Mei-Ting Qiu, Jing-Yun Wang, Hui-Juan Zhang, Li-Hua Wang, Xiao-Ping Wan

01.12.2013 | Research | Ausgabe 1/2013 Open Access

CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior

Marina Poettler, Matthias Unseld, Kira Braemswig, Andrea Haitel, Christoph C Zielinski, Gerald W Prager

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFκB pathway

Lu Qian Wang, Yok Lam Kwong, Chi Shan Bonnie Kho, Kit Fai Wong, Kwan Yeung Wong, Manuela Ferracin, George A Calin, Chor Sang Chim

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Group X secreted phospholipase A2 induces lipid droplet formation and prolongs breast cancer cell survival

Anja Pucer, Vesna Brglez, Christine Payré, Jože Pungerčar, Gérard Lambeau, Toni Petan

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer

Louisa CE Windus, Tristan T Glover, Vicky M Avery

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Targeted therapy against EGFR and VEGFR using ZD6474 enhances the therapeutic potential of UV-B phototherapy in breast cancer cells

Siddik Sarkar, Shashi Rajput, Amit Kumar Tripathi, Mahitosh Mandal

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer

Victor D Martinez, Emily A Vucic, Larissa A Pikor, Kelsie L Thu, Roland Hubaux, Wan L Lam

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Cathepsin B as a potential prognostic and therapeutic marker for human lung squamous cell carcinoma

Fengming Gong, Xingchen Peng, Can Luo, Guobo Shen, Chengjian Zhao, Liqun Zou, Longhao Li, Yaxiong Sang, Yuwei Zhao, Xia Zhao

01.12.2013 | Short communication | Ausgabe 1/2013 Open Access

Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon

Pramudita Ramadhina Prasetyanti, Cheryl Doreen Zimberlin, Michael Bots, Louis Vermeulen, Felipe De Sousa E Melo, Jan Paul Medema

01.12.2013 | Research | Ausgabe 1/2013 Open Access

R-RAS2 overexpression in tumors of the human central nervous system

Sylvia Gutierrez-Erlandsson, Pedro Herrero-Vidal, Marcos Fernandez-Alfara, Susana Hernandez-Garcia, Sandra Gonzalo-Flores, Alberto Mudarra-Rubio, Manuel Fresno, Beatriz Cubelos

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation

King Chi Chan, Choi Man Ting, Pui Shan Chan, Ming Chu Lo, Kwok Wai Lo, Jayne E Curry, Tomoko Smyth, Anne Wing Mui Lee, Wai Tong Ng, George Sai Wah Tsao, Ricky Ngok Shun Wong, Maria Li Lung, Nai Ki Mak

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin

Elaine Langenfeld, Malik Deen, Emmanuel Zachariah, John Langenfeld

01.12.2013 | Research | Ausgabe 1/2013 Open Access

miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression

Manuela Ferracin, Cristian Bassi, Massimo Pedriali, Sara Pagotto, Lucilla D’Abundo, Barbara Zagatti, Fabio Corrà, Gentian Musa, Elisa Callegari, Laura Lupini, Stefano Volpato, Patrizia Querzoli, Massimo Negrini

01.12.2013 | Research | Ausgabe 1/2013 Open Access

The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage

Orit Feldstein, Tal Nizri, Tirza Doniger, Jasmine Jacob, Gideon Rechavi, Doron Ginsberg

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis

Mejdi Moumen, Aurélie Chiche, Charles Decraene, Valérie Petit, Alberto Gandarillas, Marie-Ange Deugnier, Marina A Glukhova, Marisa M Faraldo

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

Hanneke Stegeman, Johannes HAM Kaanders, Marieke MG Verheijen, Wenny JM Peeters, Deric L Wheeler, Mari Iida, Reidar Grénman, Albert J van der Kogel, Paul N Span, Johan Bussink

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Combination of SLC administration and Tregs depletion is an attractive strategy for targeting hepatocellular carcinoma

Long Chen, Shuang Zhou, Jie Qin, Heng Hu, Huiying Ma, Binbin Liu, Xuan Wang, Jiaqi Ma, Shenglong Ye, Cuiping Zhong, Guomin Zhou, Chunmin Liang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

Lei Gong, Amber M Cumpian, Mauricio S Caetano, Cesar E Ochoa, Maria Miguelina De la Garza, Daniel J Lapid, Seyedeh Golsar Mirabolfathinejad, Burton F Dickey, Qinghua Zhou, Seyed Javad Moghaddam

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors

Rainelli B Koumangoye, Gladys N Nangami, Pamela D Thompson, Vincent K Agboto, Josiah Ochieng, Amos M Sakwe

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas

Koji Shindo, Shinichi Aishima, Kenoki Ohuchida, Kenji Fujiwara, Minoru Fujino, Yusuke Mizuuchi, Masami Hattori, Kazuhiro Mizumoto, Masao Tanaka, Yoshinao Oda

01.12.2013 | Review | Ausgabe 1/2013 Open Access

CHD1L: a novel oncogene

Wen Cheng, Yun Su, Feng Xu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms

Dhruv Kumar, Sharmila Shankar, Rakesh K Srivastava

01.12.2013 | Research | Ausgabe 1/2013 Open Access

DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival

Ying Tu, Chao Ji, Bo Yang, Zhi Yang, Hua Gu, Chun-Cheng Lu, Rong Wang, Zhong-Lan Su, Bin Chen, Wei-Ling Sun, Ji-Ping Xia, Zhi-Gang Bi, Li He

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Tylophorine, a phenanthraindolizidine alkaloid isolated from Tylophora indica exerts antiangiogenic and antitumor activity by targeting vascular endothelial growth factor receptor 2–mediated angiogenesis

Sarita Saraswati, Pawan K Kanaujia, Shakti Kumar, Ranjeet Kumar, Abdulqader A Alhaider

Aktuelle Ausgaben

Neu im Fachgebiet Onkologie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Onkologie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise