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Zeitschrift

Molecular Cancer

Molecular Cancer 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 178 Artikel )

01.12.2018 | Research | Ausgabe 1/2018 Open Access

MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer

Ying Zhang, Lu Guo, Yuhuan Li, Gui-Hai Feng, Fei Teng, Wei Li, Qi Zhou

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Extracellular vesicles as mediators of the progression and chemoresistance of pancreatic cancer and their potential clinical applications

Jiangdong Qiu, Gang Yang, Mengyu Feng, Suli Zheng, Zhe Cao, Lei You, Lianfang Zheng, Taiping Zhang, Yupei Zhao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

RETRACTED ARTICLE: Upregulation of the long non-coding RNA AFAP1-AS1 affects the proliferation, invasion and survival of tongue squamous cell carcinoma via the Wnt/β-catenin signaling pathway

Ze-you Wang, Min Hu, Min-hui Dai, Jing Xiong, Shuai Zhang, Han-jiang Wu, Shan-shan Zhang, Zhao-jian Gong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2

Hua Chen, Hong Pan, Yi Qian, Wenbin Zhou, Xiaoan Liu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion

Yu Ren, Huan-huan Jia, Yi-qi Xu, Xuan Zhou, Xiao-hui Zhao, Yun-fei Wang, Xin Song, Zhi-yan Zhu, Ting Sun, Yan Dou, Wei-ping Tian, Xiu-lan Zhao, Chun-sheng Kang, Mei Mei

01.12.2018 | Research | Ausgabe 1/2018 Open Access

STAT3-induced lncRNA HAGLROS overexpression contributes to the malignant progression of gastric cancer cells via mTOR signal-mediated inhibition of autophagy

Jin-Fei Chen, Peng Wu, Rui Xia, Jian Yang, Xin-Ying Huo, Dong-Ying Gu, Cui-Ju Tang, Wei De, Fen Yang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prospects for chimeric antigen receptor-modified T cell therapy for solid tumors

Erhao Zhang, Jieyi Gu, Hanmei Xu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Liquid biomarkers in melanoma: detection and discovery

Su Yin Lim, Jenny H. Lee, Russell J. Diefenbach, Richard F. Kefford, Helen Rizos

01.12.2018 | Research | Ausgabe 1/2018 Open Access

microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11

Wei-Luo Cai, Wen-Ding Huang, Bo Li, Tian-Rui Chen, Zhen-Xi Li, Cheng-Long Zhao, Heng-Yu Li, Yan-Mei Wu, Wang-Jun Yan, Jian-Ru Xiao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells

Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit, Yasusei Kudo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

Yanqing Liu, Xiaorui Chen, Rongjie Cheng, Fei Yang, Mengchao Yu, Chen Wang, Shufang Cui, Yeting Hong, Hongwei Liang, Minghui Liu, Chihao Zhao, Meng Ding, Wu Sun, Zhijian Liu, Feng Sun, Chenyu Zhang, Zhen Zhou, Xiaohong Jiang, Xi Chen

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

Wei Huang, Wen-Tao Wang, Ke Fang, Zhen-Hua Chen, Yu-Meng Sun, Cai Han, Lin-Yu Sun, Xue-Qun Luo, Yue-Qin Chen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway

Yang Cheng, Yun Zhu, Jiajia Xu, Min Yang, Peiyu Chen, Wanfu Xu, Junhong Zhao, Lanlan Geng, Sitang Gong

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Long non-coding RNA implicated in the invasion and metastasis of head and neck cancer: possible function and mechanisms

Xiaobo Luo, Yan Qiu, Yuchen Jiang, Fangman Chen, Lu Jiang, Yu Zhou, Hongxia Dan, Xin Zeng, Yu L. Lei, Qianming Chen

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Extracellular vesicle-derived DNA for performing EGFR genotyping of NSCLC patients

Jae Young Hur, Hee Joung Kim, Jong Sik Lee, Chang-Min Choi, Jae Cheol Lee, Min Kyo Jung, Chan Gi Pack, Kye Young Lee

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer

Wenhao Weng, Na Liu, Yuji Toiyama, Masato Kusunoki, Takeshi Nagasaka, Toshiyoshi Fujiwara, Qing Wei, Huanlong Qin, Haifan Lin, Yanlei Ma, Ajay Goel

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

A coordinate deregulation of microRNAs expressed in mucosa adjacent to tumor predicts relapse after resection in localized colon cancer

Angela Grassi, Lisa Perilli, Laura Albertoni, Sofia Tessarollo, Claudia Mescoli, Emanuele D. L. Urso, Matteo Fassan, Massimo Rugge, Paola Zanovello

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

Hao Hu, Yandong Wang, Xiangya Ding, Yuan He, Zipeng Lu, Pengfei Wu, Lei Tian, Hao Yuan, Dongfang Liu, Guodong Shi, Tianfang Xia, Jie Yin, Baobao Cai, Yi Miao, Kuirong Jiang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Chengdi Yang, Wenbo Yuan, Xiao Yang, Peng Li, Jingzi Wang, Jie Han, Jun Tao, Pengchao Li, Haiwei Yang, Qiang Lv, Wei Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting Gas6/TAM in cancer cells and tumor microenvironment

Guiling Wu, Zhiqiang Ma, Yicheng Cheng, Wei Hu, Chao Deng, Shuai Jiang, Tian Li, Fulin Chen, Yang Yang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Nischarin regulates focal adhesion and Invadopodia formation in breast cancer cells

Mazvita Maziveyi, Shengli Dong, Somesh Baranwal, Suresh K. Alahari

01.12.2018 | Review | Ausgabe 1/2018 Open Access

New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications

Ye Wang, Liya Wang, Cheng Chen, Xiaoyuan Chu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis

Pilar Mur, Richarda M. De Voer, Rubén Olivera-Salguero, Sandra Rodríguez-Perales, Tirso Pons, Fernando Setién, Gemma Aiza, Rafael Valdés-Mas, Angelo Bertini, Marta Pineda, Lilian Vreede, Matilde Navarro, Silvia Iglesias, Sara González, Joan Brunet, Alfonso Valencia, Manel Esteller, Conxi Lázaro, Geert J. P. L. Kops, Miguel Urioste, Xose S. Puente, Gabriel Capellá, Laura Valle

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

Genbao Shao, Ranran Wang, Aiqin Sun, Jing Wei, Ke Peng, Qian Dai, Wannian Yang, Qiong Lin

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma

Lucia Demkova, Lucia Kucerova

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

Shaocong Wu, Liwu Fu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer

Michaela Poliaková, Daniel M. Aebersold, Yitzhak Zimmer, Michaela Medová

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway

Haim Werner, Shilhav Meisel-Sharon, Ilan Bruchim

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Third generation EGFR TKIs: current data and future directions

Chee-Seng Tan, Nesaretnam Barr Kumarakulasinghe, Yi-Qing Huang, Yvonne Li En Ang, Joan Rou-En Choo, Boon-Cher Goh, Ross A. Soo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role and targeting of anaplastic lymphoma kinase in cancer

Carminia Maria Della Corte, Giuseppe Viscardi, Raimondo Di Liello, Morena Fasano, Erika Martinelli, Teresa Troiani, Fortunato Ciardiello, Floriana Morgillo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

Kodappully S. Siveen, Kirti S. Prabhu, Iman W. Achkar, Shilpa Kuttikrishnan, Sunitha Shyam, Abdul Q. Khan, Maysaloun Merhi, Said Dermime, Shahab Uddin

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Engineering chimeric antigen receptor-T cells for cancer treatment

Baixin Ye, Creed M. Stary, Xuejun Li, Qingping Gao, Chunsheng Kang, Xiaoxing Xiong

01.12.2018 | Review | Ausgabe 1/2018 Open Access

KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target

Marta Román, Iosune Baraibar, Inés López, Ernest Nadal, Christian Rolfo, Silvestre Vicent, Ignacio Gil-Bazo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Ramesh Butti, Sumit Das, Vinoth Prasanna Gunasekaran, Amit Singh Yadav, Dhiraj Kumar, Gopal C. Kundu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling

Ming-Chuan Hsu, Wen-Chun Hung

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Advances in studies of tyrosine kinase inhibitors and their acquired resistance

Qinlian Jiao, Lei Bi, Yidan Ren, Shuliang Song, Qin Wang, Yun-shan Wang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

Nahal Haddadi, Yiguang Lin, Glena Travis, Ann M. Simpson, Najah T. Nassif, Eileen M. McGowan

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer

Shang-Gin Wu, Jin-Yuan Shih

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The role of RICTOR downstream of receptor tyrosine kinase in cancers

Ahlem Jebali, Nicolas Dumaz

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting few to help hundreds: JAK, MAPK and ROCK pathways as druggable targets in atypical chronic myeloid leukemia

Stefania Rocca, Giovanna Carrà, Pietro Poggio, Alessandro Morotti, Mara Brancaccio

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The curious case of vacuolar ATPase: regulation of signaling pathways

Sahithi Pamarthy, Arpita Kulshrestha, Gajendra K. Katara, Kenneth D. Beaman

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer

Yuan-Chin Tsai, Tao Zeng, Wassim Abou-Kheir, Hsiu-Lien Yeh, Juan Juan Yin, Yi-Chao Lee, Wei-Yu Chen, Yen-Nien Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Targeting tumour microenvironment by tyrosine kinase inhibitor

Hor-Yue Tan, Ning Wang, Wing Lam, Wei Guo, Yibin Feng, Yung-Chi Cheng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer

Ulrich Baumgartner, Fabienne Berger, Ali Hashemi Gheinani, Sabrina Sofia Burgener, Katia Monastyrskaya, Erik Vassella

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

Yazhuo Zhang, Mengfang Xia, Ke Jin, Shufei Wang, Hang Wei, Chunmei Fan, Yingfen Wu, Xiaoling Li, Xiayu Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer

Aniello Cerrato, Roberta Visconti, Angela Celetti

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancer

Jennifer Pasquier, Marie Gosset, Caroline Geyl, Jessica Hoarau-Véchot, Audrey Chevrot, Marc Pocard, Massoud Mirshahi, Raphael Lis, Arash Rafii, Cyril Touboul

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Kinase-targeted cancer therapies: progress, challenges and future directions

Khushwant S. Bhullar, Naiara Orrego Lagarón, Eileen M. McGowan, Indu Parmar, Amitabh Jha, Basil P. Hubbard, H. P. Vasantha Rupasinghe

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy

Simona Soverini, Manuela Mancini, Luana Bavaro, Michele Cavo, Giovanni Martinelli

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

Ho Jin Lee, Phuong Chi Pham, Seung Yeob Hyun, Byungyeob Baek, Byungjin Kim, Yunha Kim, Hye-Young Min, Jeeyeon Lee, Ho-Young Lee

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Novel targeted therapies and immunotherapy for advanced thyroid cancers

George E. Naoum, Michael Morkos, Brian Kim, Waleed Arafat

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The function and therapeutic targeting of anaplastic lymphoma kinase (ALK) in non-small cell lung cancer (NSCLC)

Brandon Golding, Anita Luu, Robert Jones, Alicia M. Viloria-Petit

01.12.2018 | Review | Ausgabe 1/2018 Open Access

EGFR-TKIs resistance via EGFR-independent signaling pathways

Qian Liu, Shengnan Yu, Weiheng Zhao, Shuang Qin, Qian Chu, Kongming Wu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Expression, regulation and targeting of receptor tyrosine kinases in esophageal squamous cell carcinoma

Manoj Kumar Kashyap, Omar Abdel-Rahman

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors

Wagner Ricardo Montor, Andrei Ronaldo Oliveira Silva Escartin Salas, Fabiana Henriques Machado de Melo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia

Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of Bruton’s tyrosine kinase in B cells and malignancies

Simar Pal Singh, Floris Dammeijer, Rudi W. Hendriks

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Mechanisms of receptor tyrosine kinase activation in cancer

Zhenfang Du, Christine M. Lovly

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype

Tobias Sinnberg, Mitchell P. Levesque, Jelena Krochmann, Phil F. Cheng, Kristian Ikenberg, Francisco Meraz-Torres, Heike Niessner, Claus Garbe, Christian Busch

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities

Emily K. Kleczko, Lynn E. Heasley

01.12.2018 | Review | Ausgabe 1/2018 Open Access

New insights into long noncoding RNAs and their roles in glioma

Zixuan Peng, Changhong Liu, Minghua Wu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma

Yaojie Fu, Shanshan Liu, Shan Zeng, Hong Shen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1

Chen-Hong Ding, Chuan Yin, Shi-Jie Chen, Liang-Zhi Wen, Kai Ding, Shu-Juan Lei, Jin-Pei Liu, Jian Wang, Kai-xian Chen, Hua-liang Jiang, Xin Zhang, Cheng Luo, Wei-Fen Xie

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer

Hongyu Liu, Cheng Lei, Qin He, Zou Pan, Desheng Xiao, Yongguang Tao

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancer

Mingshan Liu, Yang Liu, Lu Deng, Dong Wang, Xueyan He, Lei Zhou, Max S. Wicha, Fan Bai, Suling Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer

Ayse Ceren Mutgan, H. Erdinc Besikcioglu, Shenghan Wang, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Clinical significance of plasma cell-free DNA mutations in PIK3CA, AKT1, and ESR1 gene according to treatment lines in ER-positive breast cancer

Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Mai Tomiguchi, Aiko Sueta, Keiichi Murakami, Hirotaka Iwase

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer

Rui Zhao, Yanli Zhang, Xin Zhang, Yongmei Yang, Xin Zheng, Xiaohui Li, Yingjie Liu, Yi Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

Yang Zhao, Yajing Liu, Li Lin, Qiong Huang, Wanming He, Shuyi Zhang, Shumin Dong, Zhaowei Wen, Jinjun Rao, Wangjun Liao, Min Shi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial–mesenchymal transition

Yue Yu, Wei Luo, Zheng-Jun Yang, Jiang-Rui Chi, Yun-Rui Li, Yu Ding, Jie Ge, Xin Wang, Xu-Chen Cao

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Loss of miR-204 expression is a key event in melanoma

Marco Galasso, Carl Morrison, Linda Minotti, Fabio Corrà, Carlotta Zerbinati, Chiara Agnoletto, Federica Baldassari, Matteo Fassan, Armando Bartolazzi, Andrea Vecchione, Gerard J. Nuovo, Gianpiero Di Leva, Stefania D’Atri, Ester Alvino, Maurizio Previati, Brian J. Nickoloff, Carlo M. Croce, Stefano Volinia

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

Kuo-Wang Tsai, Yi-Hao Lo, Hsuan Liu, Chung-Yu Yeh, You-Zuo Chen, Chao-Wen Hsu, Wei-Shone Chen, Jui-Ho Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Linc00210 drives Wnt/β-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner

Xiaomin Fu, Xiaoyan Zhu, Fujun Qin, Yong Zhang, Jizhen Lin, Yuechao Ding, Zihe Yang, Yiman Shang, Li Wang, Qinxian Zhang, Quanli Gao

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme

Sze Kiat Tan, Chiara Pastori, Clara Penas, Ricardo J. Komotar, Michael E. Ivan, Claes Wahlestedt, Nagi G. Ayad

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The decade of exosomal long RNA species: an emerging cancer antagonist

Ruihao Zhou, Kaddie Kwok Chen, Jingtao Zhang, Bufan Xiao, Zhaohao Huang, Cheng Ju, Jun Sun, Feifei Zhang, Xiao-Bin Lv, Guofu Huang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Enhanced expression of histone chaperone APLF associate with breast cancer

Aditi Majumder, Khaja Moheiddin Syed, Ananda Mukherjee, Manendra Babu Lankadasari, Juberiya Mohammed Azeez, Sreeharshan Sreeja, Kuzhuvelil B. Harikumar, Madhavan Radhakrishna Pillai, Debasree Dutta

01.12.2018 | Review | Ausgabe 1/2018 Open Access

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis

Yanyan Tang, Yi He, Ping Zhang, Jinpeng Wang, Chunmei Fan, Liting Yang, Fang Xiong, Shanshan Zhang, Zhaojian Gong, Shaolin Nie, Qianjin Liao, Xiayu Li, Xiaoling Li, Yong Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong, Can Guo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex

Chunling Ma, Fang Wang, Bing Han, Xiaoli Zhong, Fusheng Si, Jian Ye, Eddy C. Hsueh, Lynn Robbins, Susan M. Kiefer, Yanping Zhang, Pamela Hunborg, Mark A. Varvares, Michael Rauchman, Guangyong Peng

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Circular RNAs function as ceRNAs to regulate and control human cancer progression

Yaxian Zhong, Yajun Du, Xue Yang, Yongzhen Mo, Chunmei Fan, Fang Xiong, Daixi Ren, Xin Ye, Chunwei Li, Yumin Wang, Fang Wei, Can Guo, Xu Wu, Xiaoling Li, Yong Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Dr. Jekyll and Mr. Hyde: MAP17’s up-regulation, a crosspoint in cancer and inflammatory diseases

José M. García-Heredia, Amancio Carnero

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1

Liang Liu, Jimmy Ruiz, Stacey S. O’Neill, Stefan C. Grant, W. Jeffrey Petty, Meng Yang, Kexin Chen, Umit Topaloglu, Boris Pasche, Wei Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment

Zhenqiang Sun, Shuaixi Yang, Quanbo Zhou, Guixian Wang, Junmin Song, Zhen Li, Zhiyong Zhang, Jizhong Xu, Kunkun Xia, Yuan Chang, Jinbo Liu, Weitang Yuan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer

Cheng-Fei Jiang, Zhu-Mei Shi, Dong-Mei Li, Ying-Chen Qian, Yi Ren, Xiao-Ming Bai, Yun-Xia Xie, Lin Wang, Xin Ge, Wei-Tao Liu, Lin-Lin Zhen, Ling-Zhi Liu, Bing-Hua Jiang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer

Ling-Yun Lin, Li Yang, Qiang Zeng, Lin Wang, Mao-Li Chen, Ze-Hang Zhao, Guo-Dong Ye, Qi-Cong Luo, Pei-Yu Lv, Qi-Wei Guo, Bo-An Li, Jian-Chun Cai, Wang-Yu Cai

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells

Joëlle El Hajj, Eric Nguyen, Qingyuan Liu, Claire Bouyer, Eric Adriaenssens, George Hilal, Evelyne Ségal-Bendirdjian

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

RNA-Seq profiling of circular RNAs in human laryngeal squamous cell carcinomas

Cheng Lu, Xi Shi, Amanda Y. Wang, Yuan Tao, Zhenxiao Wang, Chaoping Huang, Yuehua Qiao, Hongyi Hu, Liangfa Liu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer

Gang Zhang, Shuwei Li, Jiafei Lu, Yuqiu Ge, Qiaoyan Wang, Gaoxiang Ma, Qinghong Zhao, Dongdong Wu, Weida Gong, Mulong Du, Haiyan Chu, Meilin Wang, Aihua Zhang, Zhengdong Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer

Mengqin Shen, Xiaoping Zhao, Li Zhao, Liang Shi, Shuxian An, Gang Huang, Jianjun Liu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma

Yong Wang, Xiandong Zeng, Ningning Wang, Wei Zhao, Xi Zhang, Songling Teng, Yueyan Zhang, Zhi Lu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

Xirui Liu, Yingjian Liang, Ruipeng Song, Guangchao Yang, Jihua Han, Yaliang Lan, Shangha Pan, Mingxi Zhu, Yao Liu, Yan Wang, Fanzheng Meng, Yifeng Cui, Jiabei Wang, Bo Zhang, Xuan Song, Zhaoyang Lu, Tongsen Zheng, Lianxin Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Advances on chimeric antigen receptor-modified T-cell therapy for oncotherapy

Yanyu Pang, Xiaoyang Hou, Chunsheng Yang, Yanqun Liu, Guan Jiang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression

Dandan Yin, Xiyi Lu, Jun Su, Xuezhi He, Wei De, Jinsong Yang, Wei Li, Liang Han, Erbao Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma

Jin-lan Huang, Shun-wang Cao, Qi-shui Ou, Bin Yang, Shi-hao Zheng, Jing Tang, Jing Chen, Yan-wei Hu, Lei Zheng, Qian Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a

Xiaoru Xin, Mengying Wu, Qiuyu Meng, Chen Wang, Yanan Lu, Yuxin Yang, Xiaonan Li, Qidi Zheng, Hu Pu, Xin Gui, Tianming Li, Jiao Li, Song Jia, Dongdong Lu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The hepatic pre-metastatic niche in pancreatic ductal adenocarcinoma

Demi S. Houg, Maarten F. Bijlsma

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer

Haihai Liang, Xiaoguang Zhao, Chengyu Wang, Jian Sun, Yingzhun Chen, Guoyuan Wang, Lei Fang, Rui Yang, Mengxue Yu, Yunyan Gu, Hongli Shan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation

Fatima Qadir, Mohammad Arshad Aziz, Chrisdina Puspita Sari, Hong Ma, Haiyan Dai, Xun Wang, Dhiresh Raithatha, Lucas Girotto Lagreca Da Silva, Muhammad Hussain, Seyedeh P. Poorkasreiy, Iain L. Hutchison, Ahmad Waseem, Muy-Teck Teh

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

Fengting Huang, Wenying Chen, Juanfei Peng, Yuanhua Li, Yanyan Zhuang, Zhe Zhu, Chunkui Shao, Wanling Yang, Herui Yao, Shineng Zhang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Therapeutic landscape in mutational triple negative breast cancer

Yaqin Shi, Juan Jin, Wenfei Ji, Xiaoxiang Guan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer

Steven C. Eastlack, Shengli Dong, Cristina Ivan, Suresh K. Alahari

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword

Shaoyun Wang, Peiwei Chai, Ruobing Jia, Renbing Jia

01.12.2018 | Research | Ausgabe 1/2018 Open Access

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

Yi Pan, Joanna Hung Man Tong, Raymond Wai Ming Lung, Wei Kang, Johnny Sheung Him Kwan, Wing Po Chak, Ka Yee Tin, Lau Ying Chung, Feng Wu, Simon Siu Man Ng, Tony Wing Chung Mak, Jun Yu, Kwok Wai Lo, Anthony Wing Hung Chan, Ka Fai To

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Pathological bases and clinical impact of long noncoding RNAs in prostate cancer: a new budding star

Tao Xu, Chang-ming Lin, Shu-qi Cheng, Jie Min, Li Li, Xiao-ming Meng, Cheng Huang, Lei Zhang, Zi-yu Deng, Jun Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Critical role of FOXO3a in carcinogenesis

Ying Liu, Xiang Ao, Wei Ding, Murugavel Ponnusamy, Wei Wu, Xiaodan Hao, Wanpeng Yu, Yifei Wang, Peifeng Li, Jianxun Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Knockdown of long non-coding RNA NEAT1 inhibits glioma cell migration and invasion via modulation of SOX2 targeted by miR-132

Ke Zhou, Chi Zhang, Hui Yao, Xuewen Zhang, Youxin Zhou, Yanjun Che, Yulun Huang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter

Torben Redmer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

Fuqing Hu, Haijie Li, Lu Liu, Feng Xu, Senyan Lai, Xuelai Luo, Junbo Hu, Xi Yang

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Tumor microenvironment participates in metastasis of pancreatic cancer

Bo Ren, Ming Cui, Gang Yang, Huanyu Wang, Mengyu Feng, Lei You, Yupei Zhao

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Epigenetics in ovarian cancer: premise, properties, and perspectives

Qilian Yang, Yuqing Yang, Nianxin Zhou, Kexin Tang, Wayne Bond Lau, Bonnie Lau, Wei Wang, Lian Xu, Zhengnan Yang, Shuang Huang, Xin Wang, Tao Yi, Xia Zhao, Yuquan Wei, Hongjing Wang, Linjie Zhao, Shengtao Zhou

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68

Xue Wang, Hongfei Yu, Wenjie Sun, Jianlu Kong, Lei Zhang, Jinlong Tang, Jingyu Wang, Enping Xu, Maode Lai, Honghe Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling

Srijayaprakash Babu Uppada, Saiprasad Gowrikumar, Rizwan Ahmad, Balawant Kumar, Bryan Szeglin, Xi Chen, J. Joshua Smith, Surinder K. Batra, Amar B. Singh, Punita Dhawan

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

E-cadherin signal sequence disruption: a novel mechanism underlying hereditary cancer

Joana Figueiredo, Soraia Melo, Kimberley Gamet, Tanis Godwin, Susana Seixas, João M. Sanches, Parry Guilford, Raquel Seruca

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer

Xin Li, Yuxiu Xu, Yun Ding, Changfei Li, Hong Zhao, Jiandong Wang, Songdong Meng

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer

Mercedes Herrera, Carlos Llorens, Marta Rodríguez, Alberto Herrera, Ricardo Ramos, Beatriz Gil, Antonio Candia, María Jesús Larriba, Pilar Garre, Julie Earl, Mercedes Rodríguez-Garrote, Trinidad Caldés, Félix Bonilla, Alfredo Carrato, Vanesa García-Barberán, Cristina Peña

01.12.2018 | Review | Ausgabe 1/2018 Open Access

FBXW7: a critical tumor suppressor of human cancers

Chien-Hung Yeh, Marcia Bellon, Christophe Nicot

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Thyroid cancers of follicular origin in a genomic light: in-depth overview of common and unique molecular marker candidates

Natalia Pstrąg, Katarzyna Ziemnicka, Hans Bluyssen, Joanna Wesoły

01.12.2018 | Research | Ausgabe 1/2018 Open Access

SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

Yu-Feng Yang, Mei-Fang Zhang, Qiu-Hong Tian, Jia Fu, Xia Yang, Chris Zhiyi Zhang, Hong Yang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LncRNA DLEU1 contributes to colorectal cancer progression via activation of KPNA3

Tianyou Liu, Zhiyang Han, Huanyu Li, Yuekun Zhu, Ziquan Sun, Anlong Zhu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression

Haihai Liang, Tong Yu, Yue Han, Hua Jiang, Chengyu Wang, Tianyi You, Xiaoguang Zhao, Huitong Shan, Rui Yang, Lida Yang, Hongli Shan, Yunyan Gu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of hypoxia-induced exosomes in tumor biology

Chuchu Shao, Fengming Yang, Suyu Miao, Weitao Liu, Chaoshan Wang, Yongqian Shu, Hua Shen

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance

Jie Cao, Jianchang Wei, Ping Yang, Tong Zhang, Zhuanpeng Chen, Feng He, Fang Wei, Huacui Chen, He Hu, Junbin Zhong, Zhi Yang, Wensong Cai, Wanglin Li, Qiang Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci

Virgínea de Araujo Farias, Francisco O’Valle, Santiago Serrano-Saenz, Per Anderson, Eduardo Andrés, Jesús López-Peñalver, Isabel Tovar, Ana Nieto, Ana Santos, Francisco Martín, José Expósito, F. Javier Oliver, José Mariano Ruiz de Almodóvar

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Emerging function and potential diagnostic value of circular RNAs in cancer

Xianglun Cui, Jianxun Wang, Zongjun Guo, Mengyang Li, Mingyu Li, Si Liu, Haoran Liu, Wenjing Li, Xunhua Yin, Jiaping Tao, Wenhua Xu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Tip110/SART3 regulates IL-8 expression and predicts the clinical outcomes in melanoma

Khalid Amine Timani, Balázs Győrffy, Ying Liu, Khalid S. Mohammad, Johnny J. He

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment

Weimin Zhang, Ruoxi Hong, Lin Li, Yan Wang, Peina Du, Yunwei Ou, Zitong Zhao, Xuefeng Liu, Wenchang Xiao, Dezuo Dong, Qingnan Wu, Jie Chen, Yongmei Song, Qimin Zhan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway

Xian-Zi Yang, Tian-Tian Cheng, Qing-Jun He, Zi-Ying Lei, Jun Chi, Zhen Tang, Quan-Xing Liao, Hong Zhang, Li-Si Zeng, Shu-Zhong Cui

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

Lin-Yu Sun, Xiao-Juan Li, Yu-Meng Sun, Wei Huang, Ke Fang, Cai Han, Zhen-Hua Chen, Xue-Qun Luo, Yue-Qin Chen, Wen-Tao Wang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Exosomal double-stranded DNA as a biomarker for the diagnosis and preoperative assessment of pheochromocytoma and paraganglioma

Liang Wang, Ying Li, Xin Guan, Jingyuan Zhao, Liming Shen, Jing Liu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors

Ming Yi, Dechao Jiao, Hanxiao Xu, Qian Liu, Weiheng Zhao, Xinwei Han, Kongming Wu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells

Chengwu Zeng, Sichu Liu, Shuai Lu, Xibao Yu, Jing Lai, Yifan Wu, Shaohua Chen, Liang Wang, Zhi Yu, Gengxin Luo, Yangqiu Li

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing

Qiaomei Guo, Junlei Wang, Jianfeng Xiao, Lin Wang, Xiaomeng Hu, Wenjun Yu, Gang Song, Jiatao Lou, JianFeng Chen

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma

Thomas Simon, Sotiria Pinioti, Pascale Schellenberger, Vinothini Rajeeve, Franz Wendler, Pedro R. Cutillas, Alice King, Justin Stebbing, Georgios Giamas

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

RUNX1 upregulation via disruption of long-range transcriptional control by a novel t(5;21)(q13;q22) translocation in acute myeloid leukemia

Chi-Keung Cheng, Terry H. Y. Wong, Thomas S. K. Wan, Angela Z. Wang, Natalie P. H. Chan, Nelson C. N. Chan, Chi-Kong Li, Margaret H. L. Ng

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The role of YAP/TAZ activity in cancer metabolic reprogramming

Xiaodong Zhang, Haiying Zhao, Yan Li, Di Xia, Liang Yang, Yingbo Ma, Hangyu Li

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

Fuqing Hu, Haijie Li, Lu Liu, Feng Xu, Senyan Lai, Xuelai Luo, Junbo Hu, Xi Yang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

AR–PDEF pathway promotes tumour proliferation and upregulates MYC-mediated gene transcription by promoting MAD1 degradation in ER-negative breast cancer

Lu Cao, Cong Xu, Guomin Xiang, Fang Liu, Xiaozhen Liu, Congying Li, Jing Liu, Qingxiang Meng, Jiao Jiao, Yun Niu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

CircRNA microarray profiling identifies a novel circulating biomarker for detection of gastric cancer

Weiwei Tang, Kai Fu, Handong Sun, Dawei Rong, Hanjin Wang, Hongyong Cao

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Circular RNA F-circEA-2a derived from EML4-ALK fusion gene promotes cell migration and invasion in non-small cell lung cancer

Shuangyan Tan, Dan Sun, Wenchen Pu, Qiheng Gou, Chenglin Guo, Youling Gong, Jiao Li, Yu-Quan Wei, Lunxu Liu, Yun Zhao, Yong Peng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Proteogenomic characterization and comprehensive integrative genomic analysis of human colorectal cancer liver metastasis

Yu-Shui Ma, Tao Huang, Xiao-Ming Zhong, Hong-Wei Zhang, Xian-Ling Cong, Hong Xu, Gai-Xia Lu, Fei Yu, Shao-Bo Xue, Zhong-Wei Lv, Da Fu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell lung cancer

Longqiang Wang, Xin Tong, Zhengyu Zhou, Shengjie Wang, Zhe Lei, Tianze Zhang, Zeyi Liu, Yuanyuan Zeng, Chang Li, Jun Zhao, Zhiyue Su, Cuijuan Zhang, Xia Liu, Guangquan Xu, Hong-Tao Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu, Xiaoxiang Chen, Kang Lin, Kaixuan Zeng, Xiangxiang Liu, Bei Pan, Xueni Xu, Tao Xu, Xiuxiu Hu, Li Sun, Bangshun He, Yuqin Pan, Huiling Sun, Shukui Wang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Expression signatures of exosomal long non-coding RNAs in urine serve as novel non-invasive biomarkers for diagnosis and recurrence prediction of bladder cancer

Yao Zhan, Lutao Du, Lishui Wang, Xiumei Jiang, Shujun Zhang, Juan Li, Keqiang Yan, Weili Duan, Yinghui Zhao, Lili Wang, Yunshan Wang, Chuanxin Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Exosome–transmitted long non-coding RNA PTENP1 suppresses bladder cancer progression

Rui Zheng, Mulong Du, Xiaowei Wang, Weidong Xu, Jiayuan Liang, Wenying Wang, Qiang Lv, Chao Qin, Haiyan Chu, Meilin Wang, Lin Yuan, Jing Qian, Zhengdong Zhang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis

Fei Xie, Yawei Li, Miao Wang, Chao Huang, Dan Tao, Fuxin Zheng, Hui Zhang, Fuqing Zeng, Xingyuan Xiao, Guosong Jiang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A new ALK isoform transported by extracellular vesicles confers drug resistance to melanoma cells

Giulia Cesi, Demetra Philippidou, Ines Kozar, Yeoun Jin Kim, Francois Bernardin, Guillaume Van Niel, Anke Wienecke-Baldacchino, Paul Felten, Elisabeth Letellier, Sonja Dengler, Dorothee Nashan, Claude Haan, Stephanie Kreis

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration

Xu Zhang, Hui Shi, Xiao Yuan, Pengcheng Jiang, Hui Qian, Wenrong Xu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effect of exosomal miRNA on cancer biology and clinical applications

Zhenqiang Sun, Ke Shi, Shuaixi Yang, Jinbo Liu, Quanbo Zhou, Guixian Wang, Junmin Song, Zhen Li, Zhiyong Zhang, Weitang Yuan

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Brain-derived neurotrophic factor, a new soluble biomarker for malignant pleural mesothelioma involved in angiogenesis

Patrick Smeele, Sènan Mickaël d’Almeida, Clément Meiller, Anne-Laure Chéné, Charly Liddell, Laurent Cellerin, François Montagne, Sophie Deshayes, Sarah Benziane, Marie-Christine Copin, Paul Hofman, Françoise Le Pimpec-Barthes, Henri Porte, Arnaud Scherpereel, Marc Grégoire, Didier Jean, Christophe Blanquart

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer

Courtney M Schaal, Namrata Bora-Singhal, Durairaj Mohan Kumar, Srikumar P Chellappan

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Pan-cancer analysis of tumor metabolic landscape associated with genomic alterations

Hongyoon Choi, Kwon Joong Na

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 Kip1 axis

Hui Liu, Yuan Liu, Zhaolian Bian, Jing Zhang, Rui Zhang, Xiaoyu Chen, Yanxia Huang, Yang Wang, Jinshui Zhu

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs

Maegan Miang Kee Lim, Jonathan Wei Kiat Wee, Jen Chi Soong, Damien Chua, Wei Ren Tan, Marco Lizwan, Yinliang Li, Ziqiang Teo, Wilson Wen Bin Goh, Pengcheng Zhu, Nguan Soon Tan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer

Keqiang Zhang, Jinhui Wang, Lu Yang, Yate-Ching Yuan, Tommy R. Tong, Jun Wu, Xinwei Yun, Melissa Bonner, Rajendra Pangeni, Zheng Liu, Tiger Yuchi, Jae Y. Kim, Dan J. Raz

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Therapeutic advances in anaplastic thyroid cancer: a current perspective

Shikha Saini, Kiara Tulla, Ajay V. Maker, Kenneth D. Burman, Bellur S. Prabhakar

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression

Qi Wu, Si Sun, Zhiyu Li, Qian Yang, Bei Li, Shan Zhu, Lijun Wang, Juan Wu, Jingping Yuan, Changhua Yang, Juanjuan Li, Shengrong Sun

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Structure-based assessment and network analysis of targeting 14-3-3 proteins in prostate cancer

Alex Root, Azadeh Beizaei, H. Alexander Ebhardt

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Sunitinib-suppressed miR-452-5p facilitates renal cancer cell invasion and metastasis through modulating SMAD4/SMAD7 signals

Wei Zhai, Saiyang Li, Jin Zhang, Yonghui Chen, Junjie Ma, Wen Kong, Dongkui Gong, Junhua Zheng, Wei Xue, Yunfei Xu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Role of the NLRP3 inflammasome in cancer

Maryam Moossavi, Negin Parsamanesh, Afsane Bahrami, Stephen L. Atkin, Amirhossein Sahebkar

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer

Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, Tianhui Hu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The pro-metastasis effect of circANKS1B in breast cancer

Kaixuan Zeng, Bangshun He, Burton B. Yang, Tao Xu, Xiaoxiang Chen, Mu Xu, Xiangxiang Liu, Huiling Sun, Yuqin Pan, Shukui Wang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

Hongwei Liu, Junming Bi, Wei Dong, Meihua Yang, Juanyi Shi, Ning Jiang, Tianxin Lin, Jian Huang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

LncRNA MIR31HG targets HIF1A and P21 to facilitate head and neck cancer cell proliferation and tumorigenesis by promoting cell-cycle progression

Ru Wang, Zhihong Ma, Ling Feng, Yifan Yang, Chen Tan, Qian Shi, Meng Lian, Shizhi He, Hongzhi Ma, Jugao Fang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Presence and diagnostic value of circulating tsncRNA for ovarian tumor

Eric Y. Peng, Yang Shu, Yuke Wu, Feier Zeng, Shuangyan Tan, Yun Deng, Yiqi Deng, Haining Chen, Lei Zhu, Heng Xu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

BRD4 and Cancer: going beyond transcriptional regulation

Benedetta Donati, Eugenia Lorenzini, Alessia Ciarrocchi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression

Hongjian Wang, Wei Chen, Ming Jin, Lidan Hou, Xiaoyu Chen, Rui Zhang, Jing Zhang, Jinshui Zhu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis

Renjie Wang, Sai Zhang, Xuyi Chen, Nan Li, Jianwei Li, Ruichao Jia, Yuanqing Pan, Haiqian Liang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1

Zhenzi Peng, Jun Wang, Bin Shan, Bin Li, Wei Peng, Yeping Dong, Wenwen Shi, Wenyuan Zhao, Dan He, Minghao Duan, Yuanda Cheng, Chunfang Zhang, Chaojun Duan

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effects of tumor metabolic microenvironment on regulatory T cells

Yi-an Wang, Xiao-Ling Li, Yong-Zhen Mo, Chun-Mei Fan, Le Tang, Fang Xiong, Can Guo, Bo Xiang, Ming Zhou, Jian Ma, Xi Huang, Xu Wu, Yong Li, Gui-Yuan Li, Zhao-yang Zeng, Wei Xiong

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

EphB2 stem-related and EphA2 progression-related miRNA-based networks in progressive stages of CRC evolution: clinical significance and potential miRNA drivers

Mariangela De Robertis, Tommaso Mazza, Caterina Fusilli, Luisa Loiacono, Maria Luana Poeta, Massimo Sanchez, Emanuela Massi, Giuseppe Lamorte, Maria Grazia Diodoro, Edoardo Pescarmona, Emanuela Signori, Graziano Pesole, Angelo Luigi Vescovi, Jesus Garcia-Foncillas, Vito Michele Fazio

01.12.2018 | Research | Ausgabe 1/2018 Open Access

CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells

Gang Liu, Kangmao Huang, Zhiwei Jie, Yizheng Wu, Junxin Chen, Zizheng Chen, Xiangqian Fang, Shuying Shen

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Sofie Otzen Bagger, Branden Michael Hopkinson, Deo Prakash Pandey, Mads Bak, Andreas Vincent Brydholm, Rene Villadsen, Kristian Helin, Lone Rønnov-Jessen, Ole William Petersen, Jiyoung Kim

01.12.2018 | Research | Ausgabe 1/2018 Open Access

TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling

Zhenlin Hou, Kaixuan Guo, Xuling Sun, Fuqing Hu, Qianzhi Chen, Xuelai Luo, Guihua Wang, Junbo Hu, Li Sun

01.12.2018 | Research | Ausgabe 1/2018 Open Access

LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation

Ming Shao, Qiankun Yang, Weitao Zhu, Huifang Jin, Jing Wang, Jie Song, Yongkui Kong, Xianping Lv

01.12.2018 | Research | Ausgabe 1/2018 Open Access

C-Src confers resistance to mitotic stress through inhibition DMAP1/Bub3 complex formation in pancreatic cancer

Jingjie Li, Bin Hu, Ting Wang, Wenhua Huang, Chunmin Ma, Qin Zhao, Lingang Zhuo, Tao Zhang, Yuhui Jiang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

Soon-Ki Hong, Haeseung Lee, Ok-Seon Kwon, Na-Young Song, Hyo-Ju Lee, Seungmin Kang, Jeong-Hwan Kim, Mirang Kim, Wankyu Kim, Hyuk-Jin Cha

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study

Erfei Chen, Fangfang Yang, Hongjuan He, Qiqi Li, Wei Zhang, Jinliang Xing, Ziqing Zhu, Jingjing Jiang, Hua Wang, Xiaojuan Zhao, Ruitao Liu, Lei Lei, Jing Dong, Yuchen Pei, Ying Yang, Junqiang Pan, Pan Zhang, Shuzhen Liu, Le Du, Yuan Zeng, Jin Yang

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

Comparative proteogenomic analysis of right-sided colon cancer, left-sided colon cancer and rectal cancer reveals distinct mutational profiles

Robin Imperial, Zaheer Ahmed, Omer M. Toor, Cihat Erdoğan, Ateeq Khaliq, Paul Case, James Case, Kevin Kennedy, Lee S. Cummings, Niklas Melton, Shahzad Raza, Banu Diri, Ramzi Mohammad, Bassel El-Rayes, Timothy Pluard, Arif Hussain, Janakiraman Subramanian, Ashiq Masood

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Multipotent mesenchymal stromal cells play critical roles in hepatocellular carcinoma initiation, progression and therapy

Zeli Yin, Keqiu Jiang, Rui Li, Chengyong Dong, Liming Wang

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