Ausgabe Sonderheft 1/2012
Proceedings of the 2011 International Conference on Molecular Neurodegeneration
Inhalt (75 Artikel)
Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development
Ferid Murad
Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease
Ping Gong, Jelita Roseman, Kulandaivelu S Vetrivel, Vytautas P Bindokas, Lois A Zitzow, Satyabrata Kar, Angèle T Parent, Gopal Thinakaran
BACE1, the Alzheimer's beta-secretase enzyme, in health and disease
Robert Vassar
Sorting out the cell biology of Alzheimer’s disease: focus on BACE1 and APP
Wim Annaert
Presenilins in Alzheimer’s disease and frontotemporal dementia
Jie Shen
β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia
Robert Tamayev, Shuji Matsuda, Luciano D’Adamio
ApoER2 trafficking, processing and signaling and its participation in neurodegeneration
María-Paz Marzolo
Elucidating the mechanisms underlying Alzheimer's disease-associated genetic polymorphisms
Steven Estus
Does axonopathy play a role in Parkinson's disease?
Karen L O’Malley, Jo Ann Antenor-Dorsey, Jeong Sook Kim-Han
Abstract withdrawn
The role of DJ-1 in anti-apoptosis
Haigang Ren, Kai Fu, Jun Fan, Guanghui Wang
Neuropathology of transgenic HD animal models
Xiaojiang Li, Shihua Li
Novel circuitry and molecular pathogenic mechanisms in Huntington's disease
X William Yang
Epigenetic gambling & epigenetic drift as potential mechanisms underlying the quasi-stochastic distributions of late life neurodegenerative disorders
George M Martin
The roles of fractalkine signaling in neurodegenerative disease
Bruce Lamb
Identifying an APP-binding protein in neuronal cell death
Yunwu Zhang, Huaxi Xu
Reticulon 3 aggregation and its role in the formation of dystrophic neurites
Riqiang Yan
Prevention of cognitive deficits in Alzheimer’s mouse model by elevating brain magnesium
Guosong Liu
Selenite benefits embryonic stem cells therapy in the animal models of Parkinson’s disease through inhibiting inflammation
Lipeng Tian, Shi Zhang, Liang Xu, Wen Li, Ying Wang, Wei Chen, Jianqing Ding, Shengdi Chen
Disruption of specific GDNF receptor subtype signaling impairs cortical neuronal survival in Alzheimer’s brains
Yoshihiro Konishi, Libang Yang, Ping He, Kristina Lindholm, Bai Lu, Rena Li, Yong Shen
Aggregation of TDP-43 fragments triggers cellular aberrant function: implication in neurodegeneration
Meixia Che, Leilei Jiang, Chenjie Zhou, Yajun Jiang, Hongyu Hu
Dynamic neuronal regulatory network during the progression of Alzheimer’s disease suggests an adaptive survival strategy
Jiya Sun, Xuemei Feng, Dapeng Liang, Yong Duan, Hongxing Lei
Molecular mechanisms for simvastatin-mediated enhancement of synaptic plasticity
Robert A Mans, Lori L McMahon, Ling Li
Wnt signaling receptor LRP6 interacts with amyloid precursor protein and regulates its trafficking and processing
Chia-Chen Liu, Hyang-Sook Hoe, Guojun Bu
Chronic cerebral hypoperfusion induces UCP2 expression by decreasing mitochondrial respiratory activities in aging rat brain
Minna Gao, Li Liu, Linhui Wang, Gang Yu, Yu Li
Upregulation of astrocytic α7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology
Wenfeng Yu, Naguib Mechawar, Slavica Krantic, Jean-Guy Chabot, Rémi Quirion
Application of bimolecular fluorescence complementation in studying the topology of polytopic proteins
Xingya Chang, Fei Dou
Implication of lipid metabolism disturbance and Alzheimer’s disease: focus on the lipoprotein lipase plays an important role in learning and memory function
Dehua Chui, Ting Zhou, Liang Zhou, Huan Yang, Xinying Liu, Tingting Liu, Jia Yu, Yi Liu, Xue Fei Wu, Hui Zhang, Dongsheng Fan
Formononetin could increase soluble-APPα secretion by up-regulating ADAM10 level
Ting Zhou, Miao Shun, Liang Zhou, Huan Yang, Kaiyin Zhong, Ximeng Zhang, Hui Zhang, Dongsheng Fan, Dehua Chui
DnaJB6: an indirect interaction protein of 15-kDa selenoprotein
Jing Tian, Qiong Liu, Jiazuan Ni
EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation
Ying Yang, Xiaogang Shu, Dan Liu, Lei Pei, Lingqiang Zhu, Qing Tian, Jianzhi Wang, Youming Lu
A tet-on system for Drd1a-expressing cells
Fayi Yao, Robert G MacKenzie
Beneficial effects of tri-lithium pyrroloquinoline quinonein on behaviors and pathology in a mouse model of Alzheimer’s disease
Lei Zhao, Neng Gong, Xiaojing Sun, Zhe Yu, Qi Fang, Na Zhao, Xiaoli Pan, Tianle Xu, Chunjiu Zhong
Chronic cerebral hypoperfusion induces ABCA1 and apolipoprotein A I mediated cellular cholesterol efflux by activating LXR/RXR in aging rat brain
Linhui Wang, Mingyuan Tian, Li Tang, Bin Liu, Yu Li
Neuroprotective efficacy of ABCA1 and HDL in aging rats with cerebrovascular hypoperfusion
Linhui Wang, Mingyuan Tian, Gang Yu, Hongchi Luo, Yu Li
Curcumin preserves cognitive function and improve serum HDL in chronic cerebral hypoperfusion aging-rats
Mingyuan Tian, Linhui Wang, Gang Yu, Bin Liu, Yu Li
Effects of an early- and late-stage treatment with Geniposide on cognitive dysfunction in a transgenic mouse model relevant to Alzheimer's disease
Lei Wang, Shijun Yan, Wensheng Zhang
Puromycin-sensitive aminopeptidase is involved in wild-type huntingtin clearance
Guijie Ren, Zonghcai Ma, Maria Hui, Lili C Kudo, Koon-Sea Hui, Stanislav L Karsten
The role of ATP-sensitive potassium channels on DMT1-mediated ferrous iron uptake in SK-N-SH cells
Xixun Du, Huamin Xu, Ning Song, Hong Jiang, Junxia Xie
Curcumin promotes cholesterol efflux from brain through LXR/RXR-ABCA1-apoA1 pathway in chronic cerebral hypoperfusion aging-rats
Mingyuan Tian, Linhui Wang, Gang Yu, Bin Liu, Yu Li
The protective effects of TanIIA on neurotoxicity induced by β-amyloid protein through the Cdk5/P35 pathway in cultured primary neurons
Lili Shi, Weina Yang, Yihua Qian, Jianshui Zhang, Xinlin Chen, Yong Liu
The study of the association of the p35 rs17852832 SNP polymorphism with Alzheimer’s disease
Lili Shi, Yihua Qian, Xiaodan Hu, Hua Han, Yong Liu
Curcumin protects brain from oxidative stress through inducing expression of UCP2 in chronic cerebral hypoperfusion aging-rats
Li Liu, Peng Zhang, Yu Li, Gang Yu
Acetylcholinesterase blocks cleavage of APP by γ-secretase in 293 cells and mouse brain
Xin Niu, Xuejin Zhang, Jing Xie, Xuejun Zhang
Protective effect of uric acid against 6-OHDA-induced injury in SH-SY5Y cells
Tingting Huang, Li Gong, Weifeng Luo, Lifang Hu, Chunfeng Liu
Effects of nicotine on gastric myoelectrical activity in ICR mice
Eileen Hui-Chuan Wang, Nathalie Percie Du Sert, John Anthony Rudd
Curcumin protects SH-SY5Y cells from oxidative stress by up-regulating HO-1 via Phosphatidylinositol 3 Kinase/Akt/Nrf-2 and down-regulating HO-2
Wenke Yin, Xiong Zhang, Xiaodong Shi, Yu Li
Gastrodin improves learning behavior in a rat model of Alzheimer's disease induced by intra-hippocampal Aβ 1-40 injection
Xing Liu, Mengya Wang
Retrovirus mediated hypoxia-responsive element-regulated neurotrophin-3 transduction attenuates brain injury following focal cerebral ischemia in rats
Junfeng Zhang, Qindong Shi, Pengbo Yang, Xi Xu, Xinlin Chen, Cunfang Qi, Jianshui Zhang, Haixia Lu, Pengbo Zhang, Bingqiao Zhao, Ping Zheng, Yong Liu
Retroviral vector-mediated hypoxia-regulated neurotrophin-3 gene transfer reduces apoptosis induced by hypoxia in PC12 cells
Junfeng Zhang, Qindong Shi, Xinlin Chen, Pengbo Yang, Cunfang Qi, Jianshui Zhang, Haixia Lu, Lingyu Zhao, Bingqiao Zhao, Ping Zheng, Yong Liu
mGluR5 regulated proliferation of neural stem cells after hypoxia with activation of MAPK signaling pathway
Lingyu Zhao, Qian Jiao, Xinlin Chen, Pengbo Yang, Bingqiao Zhao, Ping Zheng, Yong Liu
Self-renewal potential of NPCs decreased in vitro during human embryonic brain development with reduced activation of mitogen-activated protein kinases signaling
Lingyu Zhao, Qian Jiao, Xinlin Chen, Pengbo Yang, Bingqiao Zhao, Ping Zheng, Yong Liu
Oxidative DNA damage triggers ProNGF-Mediated apoptosis in the striatum of 6-OHDA-treated rats
Tao Wang, Pingping Zuo, Piu Chan
C-terminal part of alpha-synuclein mediates its activity in promoting proliferation of dopaminergic cells
Juanjuan Yin, Tao Wang, Junyan Han, Chen Zhang, Qiulan Ma, Xin Li, Furong Cheng, Guangwei Liu, Yaohua Li, Kenji Uéda, Piu Chan, Shun Yu
Exploring the role of common regulatory variants in the etiology of late-onset Alzheimer’s disease
Hao Wang, Min Zhu, Jian Wang, Yue Sun, Yu Tao, Qin He, Xiang Xu, Li Chen, David Saffen
Investigation of genetic variants regulating the expression of metabotropic glutamate receptor, subtype 5 (GRM5) mRNA in human brain
Jian Wang, David Saffen
Involvement of 5-lipoxygenase/cysteinyl leukotriene receptor 1 in rotenone- and MPP+-induced BV2 microglial activation
Yanfang Wang, Xiaoyan Zhang, Chengtan Li, Jianbo Zhao, Erqing Wei, Lihui Zhang
Alzheimer’s disease candidate gene PION is differentially expressed in human prefrontal cortex
Min Zhu, David Saffen
Neuroprotective effect of Curcumin involved in increasing the protein levels of UCP2 and inhibiting oxidative stress induced by chronic cerebral ischemia in vitro
Minna Gao, Li Liu, Peng Zhang, Gang Yu, Yu Li
Testosterone regulates Arp2/3 expression by DNA methylation in hippocampus
Liang Zhou, Ximeng Zhang, Xuefei Wu, Huan Yang, Kaiyin Zhong, Hecheng Wang, Ting Zhou, Tianxiao Sheng, Yawei Tong, Dongsheng Fan, Dehua Chui
Chinese herbal extract reduces Amyloid-β induced neurotoxicity through inhibiting NF-κB signaling pathway in neuronal cells
Xuehua Wu, Yan Yu, Liang Zhou, Hecheng Wang, Huan Yang, Kaiyin Zhong, Ximeng Zhang, Hui Zhang, Dongsheng Fan, Dehua Chui
(-)-Epigallocatechin-3-gallate ameliorates learning and memory impairments by attenuating peroxidation in APP/PS1 transgenic mice
Mingyan Liu, Fujun Chen, Tao Lin, Lutian Yao, Miao He, Zheng Zhu, Zhimin Yao, Shuang Wang, Weifan Yao, Zhenjie Zhang, Qiushi Tang, Minjie Wei
EGCG and nimodipine improve the symptoms of AD by inhibiting [Ca2+]i in hippocampal neurons of APP/PS1 transgenic mice
Shuang Wang, Mingyan Liu, Zhenjie Zhang, Weifan Yao, Qiushi Tang, Minjie Wei
Preventive effect of Curcumin on AD through increasing PS1/E-cadherin/beta-catenin complex mediated by E-cadherin
Xiong Zhang, Wenke Yin, Xiaodong Shi, Yu Li
Some selenoproteins possibly involved in the development of Alzheimer’s disease: hints from the interaction proteins
Qiong Liu, Chao Wang, Xifeng Qiao, Ping Chen, Jing Tian, Jiazuan Ni
Protective effect of Curcumin on chronic cerebral ischemia by altering expression of α- synuclein in 2VO model
Gang Yu, Li Liu, Peng Zhang, Yu Li
Establishment and evaluation of transgenic models of Alzheimer's disease with senescence accelerated background
Wenjuan Zhao, KengHoe Lok, Hong Zhao, Anyang Sun, Ming Yin
N-cadherin-ERα-Src signal models mediate the synergistic potentiation of activation of PI3K/Akt signal pathway in injured dopaminergic neurons by GDNF and E2
Zixiao Shi, Meng Wang, Ye Xiong, Yaping Liu, Xiaozhou Wang, Jing Liu, Li Li, Dianshuai Gao