Ausgabe 1/2015
Inhalt (74 Artikel)
Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptors
Manouela V Valtcheva, Steve Davidson, Chengshui Zhao, Michael Leitges, Robert W Gereau IV
Types of skin afferent fibers and spinal opioid receptors that contribute to touch-induced inhibition of heart rate changes evoked by noxious cutaneous heat stimulation
Nobuhiro Watanabe, Mathieu Piché, Harumi Hotta
Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results
Hongwei Yu, Gregory Fischer, Allison D Ebert, Hsiang-En Wu, Xiaowen Bai, Quinn H Hogan
Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40
Prasanna Karki, Takashi Kurihara, Tomoya Nakamachi, Jun Watanabe, Toshihide Asada, Tatsuki Oyoshi, Seiji Shioda, Megumu Yoshimura, Kazunori Arita, Atsuro Miyata
Alleviation of neuropathic pain by regulating T-type calcium channels in rat anterior cingulate cortex
Feng-Yan Shen, Zhi-Yu Chen, Wei Zhong, Li-Qing Ma, Chong Chen, Zhou-Jing Yang, Wei-Lin Xie, Ying-Wei Wang
Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons
Yasuko Ikeda-Miyagawa, Kimiko Kobayashi, Hiroki Yamanaka, Masamichi Okubo, Shenglan Wang, Yi Dai, Hideshi Yagi, Munetaka Hirose, Koichi Noguchi
A [14C]iodoantipyrine study of inter-regional correlations of neural substrates following central post-stroke pain in rats
Hsiang-Chin Lu, Wei-Jen Chang, Yung-Hui Kuan, Andrew Chih-Wei Huang, Bai Chuang Shyu
Paclitaxel induces acute pain via directly activating toll like receptor 4
Xisheng Yan, Dylan W Maixner, Ruchi Yadav, Mei Gao, Pei Li, Michael G Bartlett, Han-Rong Weng
The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury
Miho Asahara, Nobuko Ito, Takehiko Yokomizo, Motonao Nakamura, Takao Shimizu, Yoshitsugu Yamada
Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain
Vinicius M Gadotti, Agustin Garcia Caballero, N Daniel Berger, Clare M Gladding, Lina Chen, Tom A Pfeifer, Gerald W Zamponi
Protease-activated receptors in the Achilles tendon–a potential explanation for the excessive pain signalling in tendinopathy
Jens Christensen, Håkan Alfredson, Gustav Andersson
N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans
Andrea Truini, Serena Piroso, Erica Pasquale, Serena Notartomaso, Giulia Di Stefano, Roberta Lattanzi, Giuseppe Battaglia, Ferdinando Nicoletti, Giorgio Cruccu
Sensitization of P2X3 receptors by cystathionine β-synthetase mediates persistent pain hypersensitivity in a rat model of lumbar disc herniation
Qianliang Wang, Hongyan Zhu, Kang Zou, Bo Yuan, You-Lang Zhou, Xinghong Jiang, Jun Yan, Guang-Yin Xu
Anxiolytic-like effects of translocator protein (TSPO) ligand ZBD-2 in an animal model of chronic pain
Dong-sheng Wang, Zhen Tian, Yan-yan Guo, Hong-liang Guo, Wen-bo Kang, Shuo Li, Ya-ting Den, Xu-bo Li, Bing Feng, Dan Feng, Jian-ning Zhao, Gang Liu, Ming-gao Zhao
Properties of sodium currents in neonatal and young adult mouse superficial dorsal horn neurons
Melissa A Tadros, Kristen E Farrell, Brett A Graham, Alan M Brichta, Robert J Callister
Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain
Yi Zhang, Yong Chen, Wolfgang Liedtke, Fan Wang
MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway
Ran Zhang, Min Huang, Zhijuan Cao, Jieyu Qi, Zilong Qiu, Li-Yang Chiang
In vivo patch-clamp analysis of the antinociceptive actions of TRPA1 activation in the spinal dorsal horn
Manabu Yamanaka, Wataru Taniguchi, Naoko Nishio, Hiroshi Hashizume, Hiroshi Yamada, Munehito Yoshida, Terumasa Nakatsuka
Chronic dry eye symptoms after LASIK: parallels and lessons to be learned from other persistent post-operative pain disorders
Alexandra E Levitt, Anat Galor, Jayne S Weiss, Elizabeth R Felix, Eden R Martin, Dennis J Patin, Konstantinos D Sarantopoulos, Roy C Levitt
Experimental evidence for alleviating nociceptive hypersensitivity by single application of capsaicin
Xiao-Li Ma, Fang-Xiong Zhang, Fei Dong, Lan Bao, Xu Zhang
In situ patch-clamp recordings from Merkel cells in rat whisker hair follicles, an experimental protocol for studying tactile transduction in tactile-end organs
Ryo Ikeda, Jennifer Ling, Myeounghoon Cha, Jianguo G Gu
Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons
Yukari Hatakeyama, Kenji Takahashi, Makoto Tominaga, Hideo Kimura, Toshio Ohta
Minocycline does not affect long-term potentiation in the anterior cingulate cortex of normal adult mice
Qian Song, Ming-Gang Liu, Min Zhuo
Sodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin
Frank L Rice, Phillip J Albrecht, James P Wymer, Joel A Black, Ingemar SJ Merkies, Catharina G Faber, Stephen G Waxman
Current gene therapy using viral vectors for chronic pain
Jean-Marc G Guedon, Shaogen Wu, Xuexing Zheng, Caroline C Churchill, Joseph C Glorioso, Ching-Hang Liu, Shue Liu, Lucy Vulchanova, Alex Bekker, Yuan-Xiang Tao, Paul R Kinchington, William F Goins, Carolyn A Fairbanks, Shuanglin Hao
Pain perception in acute model mice of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Jihye Park, Chae-Seok Lim, Hyunhyo Seo, Chung-Ah Park, Min Zhuo, Bong-Kiun Kaang, Kyungmin Lee
Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons
Dmytro E Duzhyy, Viacheslav Y Viatchenko-Karpinski, Eugen V Khomula, Nana V Voitenko, Pavel V Belan
Released lipids regulate Transient Receptor Potential Channel (TRP)-dependent oral cancer pain
Shivani Ruparel, Michelle Bendele, Ashley Wallace, Dustin Green
Novel expression pattern of neuropeptide Y immunoreactivity in the peripheral nervous system in a rat model of neuropathic pain
Claire Magnussen, Shih-Ping Hung, Alfredo Ribeiro-da-Silva
mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia
Brianna Marie Lutz, Sam Nia, Ming Xiong, Yuan-Xiang Tao, Alex Bekker
The opioid peptide dynorphin A induces leukocyte responses via integrin Mac-1 (αMβ2, CD11b/CD18)
Nataly P. Podolnikova, Julie A. Brothwell, Tatiana P. Ugarova
Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase
David J. Marcus, Michael Zee, Alex Hughes, Matthew B. Yuill, Andrea G. Hohmann, Ken Mackie, Josée Guindon, Daniel J. Morgan
PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
Sonja K Bareiss, Elizabeth Dugan, Kori L Brewer
Spinal cord stimulation modulates supraspinal centers of the descending antinociceptive system in rats with unilateral spinal nerve injury
Toshiharu Tazawa, Yoshinori Kamiya, Ayako Kobayashi, Kensuke Saeki, Masahito Takiguchi, Yusuke Nakahashi, Hironobu Shinbori, Kengo Funakoshi, Takahisa Goto
Function and postnatal changes of dural afferent fibers expressing TRPM8 channels
Lynn Ren, Ajay Dhaka, Yu-Qing Cao
Mechanisms underlying clinical efficacy of Angiotensin II type 2 receptor (AT2R) antagonist EMA401 in neuropathic pain: clinical tissue and in vitro studies
Uma Anand, Yiangos Yiangou, Marco Sinisi, Michael Fox, Anthony MacQuillan, Tom Quick, Yuri E Korchev, Chas Bountra, Tom McCarthy, Praveen Anand
Expression changes of microRNA-1 and its targets Connexin 43 and brain-derived neurotrophic factor in the peripheral nervous system of chronic neuropathic rats
Elena Neumann, Henning Hermanns, Franziska Barthel, Robert Werdehausen, Timo Brandenburger
Temporal dynamics of anxiety phenotypes in a dental pulp injury model
Lin Shang, Tian-Le Xu, Fei Li, Jiansheng Su, Wei-Guang Li
Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats
Jorge Baruch Pineda-Farias, Paulino Barragán-Iglesias, Emanuel Loeza-Alcocer, Jorge E Torres-López, Héctor Isaac Rocha-González, Francisca Pérez-Severiano, Rodolfo Delgado-Lezama, Vinicio Granados-Soto
Distribution of raphespinal fibers in the mouse spinal cord
Huazheng Liang, Shaoshi Wang, Richard Francis, Renee Whan, Charles Watson, George Paxinos
Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain
Bao-Chun Jiang, Wen-Xing Sun, Li-Na He, De-Li Cao, Zhi-Jun Zhang, Yong-Jing Gao
G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy
Chuang Lyu, Jan Mulder, Swapnali Barde, Kristoffer Sahlholm, Hugo Zeberg, Johanna Nilsson, Peter Århem, Tomas Hökfelt, Kaj Fried, Tie-Jun Sten Shi
KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia
Alaa A Abd-Elsayed, Ryo Ikeda, Zhanfeng Jia, Jennifer Ling, Xiaozhuo Zuo, Min Li, Jianguo G Gu
Koumine enhances spinal cord 3α-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain
Hong-Qiang Qiu, Ying Xu, Gui-Lin Jin, Jian Yang, Ming Liu, Su-Ping Li, Chang-Xi Yu
Amelioration of the reduced antinociceptive effect of morphine in the unpredictable chronic mild stress model mice by noradrenalin but not serotonin reuptake inhibitors
Soichiro Ide, Hiroshi Satoyoshi, Masabumi Minami, Masamichi Satoh
p38 phosphorylation in medullary microglia mediates ectopic orofacial inflammatory pain in rats
Masaaki Kiyomoto, Masamichi Shinoda, Kuniya Honda, Yuka Nakaya, Ko Dezawa, Ayano Katagiri, Satoshi Kamakura, Tomio Inoue, Koichi Iwata
Short-term anesthesia inhibits formalin-induced extracellular signal-regulated kinase (ERK) activation in the rostral anterior cingulate cortex but not in the spinal cord
Keri K Tochiki, Maria Maiarù, James R C Miller, Stephen P Hunt, Sandrine M Géranton
Recruitment of dorsal midbrain catecholaminergic pathways in the recovery from nerve injury evoked disabilities
David Mor, James W M Kang, Peter Wyllie, Vignaraja Thirunavukarasu, Hayden Houlton, Paul J Austin, Kevin A Keay
Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain
Jeremy M. Thompson, Guangchen Ji, Volker Neugebauer
Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms
Martin Kaczocha, Sherrye T. Glaser, Thomas Maher, Brendan Clavin, John Hamilton, Joseph O’Rourke, Mario Rebecchi, Michelino Puopolo, Yuji Owada, Panayotis K. Thanos
Leukotriene enhances NMDA-induced inward currents in dorsal horn neurons of the rat spinal cord after peripheral nerve injury
Yasukuni Kiyoyuki, Wataru Taniguchi, Masamichi Okubo, Hiroki Yamanaka, Kimiko Kobayashi, Naoko Nishio, Terumasa Nakatsuka, Koichi Noguchi
Limited changes in spinal lamina I dorsal horn neurons following the cytotoxic ablation of non-peptidergic C-fibers
Abeer W. Saeed, Sophie A. Pawlowski, Alfredo Ribeiro-da-Silva
Anoctamin-1 Cl− channels in nociception: activation by an N-aroylaminothiazole and capsaicin and inhibition by T16A[inh]-A01
Farah Deba, Bret F. Bessac
Alleviating neuropathic pain mechanical allodynia by increasing Cdh1 in the anterior cingulate cortex
Wei Tan, Wen-Long Yao, Rong Hu, You-You Lv, Li Wan, Chuan-Han Zhang, Chang Zhu
Pirt contributes to uterine contraction-induced pain in mice
Changming Wang, Zhongli Wang, Yan Yang, Chan Zhu, Guanyi Wu, Guang Yu, Tunyu Jian, Niuniu Yang, Hao Shi, Min Tang, Qian He, Lei Lan, Qin Liu, Yun Guan, Xinzhong Dong, Jinao Duan, Zongxiang Tang
Mitochondrial and bioenergetic dysfunction in trauma-induced painful peripheral neuropathy
Tony K. Y. Lim, Malena B. Rone, Seunghwan Lee, Jack P. Antel, Ji Zhang
Sympathetic fibre sprouting in the skin contributes to pain-related behaviour in spared nerve injury and cuff models of neuropathic pain
Francisney P. Nascimento, Claire Magnussen, Noosha Yousefpour, Alfredo Ribeiro-da-Silva
Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons
Cindy Barbosa, Zhi-Yong Tan, Ruizhong Wang, Wenrui Xie, Judith A. Strong, Reesha R. Patel, Michael R. Vasko, Jun-Ming Zhang, Theodore R. Cummins
Erratum to: Temporal dynamics of anxiety phenotypes in a dental pulp injury model
Lin Shang, Tian-Le Xu, Fei Li, Jiansheng Su, Wei-Guang Li
Novel cytogenic and neurovascular niches due to blood–brain barrier compromise in the chronic pain brain
Maral Tajerian, J. David Clark
Transient, activity dependent inhibition of transmitter release from low threshold afferents mediated by GABAA receptors in spinal cord lamina III/IV
Chiara Betelli, Amy B. MacDermott, Rita Bardoni
Contribution of Piezo2 to endothelium-dependent pain
Luiz F. Ferrari, Oliver Bogen, Paul Green, Jon D. Levine
MicroRNA circulating in the early aftermath of motor vehicle collision predict persistent pain development and suggest a role for microRNA in sex-specific pain differences
Sarah D. Linnstaedt, Margaret G. Walker, Joel S. Parker, Eunice Yeh, Robert L. Sons, Erin Zimny, Christopher Lewandowski, Phyllis L. Hendry, Kathia Damiron, Claire Pearson, Marc-Anthony Velilla, Brian J. O’Neil, Jeffrey Jones, Robert Swor, Robert Domeier, Scott Hammond, Samuel A. McLean
The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients
Xiaoyan Chen, Rosa B. Spaeth, Sonya G. Freeman, Donna Moxley Scarborough, Javeria A. Hashmi, Hsiao-Ying Wey, Natalia Egorova, Mark Vangel, Jianren Mao, Ajay D. Wasan, Robert R. Edwards, Randy L. Gollub, Jian Kong
p38 MAPK mediates glial P2X7R-neuronal P2Y1R inhibitory control of P2X3R expression in dorsal root ganglion neurons
Yong Chen, Guangwen Li, Li-Yen Mae Huang
Transient receptor potential ankyrin 1 that is induced in dorsal root ganglion neurons contributes to acute cold hypersensitivity after oxaliplatin administration
Ken Yamamoto, Noriko Chiba, Terumasa Chiba, Toshie Kambe, Kenji Abe, Kazuyoshi Kawakami, Iku Utsunomiya, Kyoji Taguchi
The effect of kinin B1 receptor on chronic itching sensitization
Yuying Liu, Jianhua Liu, Mengran Li, Sailin Dai, Jiexian Liang, Wenjin Ji
Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization
Anna Marchenkova, Sandra Vilotti, Elsa Fabbretti, Andrea Nistri
The role of Nav1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia
Ana Paula Luiz, Olga Kopach, Sonia Santana-Varela, John N. Wood
Short-term pre- and post-operative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception
Jing Cao, Po-Kai Wang, Vinod Tiwari, Lingli Liang, Brianna Marie Lutz, Kun-Ruey Shieh, Wei-Dong Zang, Andrew G. Kaufman, Alex Bekker, Xiao-Qun Gao, Yuan-Xiang Tao
Impairments of the primary afferent nerves in a rat model of diabetic visceral hyposensitivity
Li Dong, Xizi Liang, Biying Sun, Xiaowei Ding, Hongxiu Han, Guohua Zhang, Weifang Rong
Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats
Farinaz Nasirinezhad, Shyam Gajavelli, Blake Priddy, Stanislava Jergova, James Zadina, Jacqueline Sagen
Spinal autophagy is differently modulated in distinct mouse models of neuropathic pain
Laura Berliocchi, Maria Maiarù, Giuseppe Pasquale Varano, Rossella Russo, Maria Tiziana Corasaniti, Giacinto Bagetta, Cristina Tassorelli