Erschienen in:
11.04.2019 | Research Letter
Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus
verfasst von:
Chantal Kopecky, Yuliya Lytvyn, Oliver Domenig, Marlies Antlanger, Johannes J. Kovarik, Christopher C. Kaltenecker, Marko Poglitsch, Bruce A. Perkins, Kerry-Anne Rye, David Z. I. Cherney, Marcus D. Säemann
Erschienen in:
Diabetologia
|
Ausgabe 6/2019
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Excerpt
To the Editor: Sodium–glucose cotransporter-2 (SGLT-2) inhibitors are a highly promising class of glucose-lowering therapies and have been found to reduce cardiovascular and kidney disease risk in patients with type 2 diabetes [
1‐
3]. The mechanisms underlying these cardio- and renoprotective effects of SGLT-2 inhibition are, however, incompletely understood and it is not known if these beneficial effects are also evident in people with type 1 diabetes. …