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Erschienen in: Der Anaesthesist 9/2019

06.09.2019 | Allgemeinanästhesie | Leitthema

„Tiefe Narkose – schlechte Narkose?“

verfasst von: M.-T. Georgii, G. Schneider

Erschienen in: Die Anaesthesiologie | Ausgabe 9/2019

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Zusammenfassung

Neben tiefen Narkoseindexwerten wurden insbesondere Burst-Suppression-Muster und deren Zusammenhang mit postoperativem Delir und postoperativer Mortalität untersucht. Dreizehn der im Folgenden beschriebenen Studien aus dem letzten Jahrzehnt liefern Hinweise, dass dokumentierte tiefe Narkoseindizes oder Burst-Suppression-Muster das Risiko für entweder ein postoperatives kognitives Defizit oder die Mortalität erhöhen. Es handelt sich jedoch überwiegend um sekundäre Datenanalysen oder retrospektive Observationsstudien. Die erste prospektive Interventionsstudie zu „triple low“ konnte diesen Zusammenhang nicht nachweisen. Derzeit werden die ersten prospektiven Interventionsstudien zur Vermeidung exzessiver EEG-Suppression durchgeführt. Die Ergebnisse würden nicht nur die Formulierung evidenzbasierter Empfehlungen ermöglichen, sondern sollen auch Hinweise und Anhaltspunkte liefern, ob es sich bei den oben genannten Beobachtungen um einen kausalen Zusammenhang oder ein Epiphänomen handelt.
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Metadaten
Titel
„Tiefe Narkose – schlechte Narkose?“
verfasst von
M.-T. Georgii
G. Schneider
Publikationsdatum
06.09.2019
Verlag
Springer Medizin
Erschienen in
Die Anaesthesiologie / Ausgabe 9/2019
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI
https://doi.org/10.1007/s00101-019-00647-y

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