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Erschienen in: Techniques in Coloproctology 10/2021

22.07.2021 | Original Article

Morbidity and costs of diverting ileostomy in transanal total mesorectal excision with primary anastomosis for rectal cancer

verfasst von: J. C. Hol, F. Bakker, N. T. van Heek, G. M. de Jong, F. M. Kruyt, C. Sietses

Erschienen in: Techniques in Coloproctology | Ausgabe 10/2021

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Abstract

Background

The role of diverting ileostomy is debated in rectal cancer surgery with primary anastomosis. The aim of this study was to evaluate the associated morbidity and hospital costs of diversion after sphincter saving TaTME surgery.

Methods

All patients undergoing TaTME with primary anastomosis for rectal cancer between January 2012 and December 2019 in a single centre in the Netherlands were included. Patients with diverting ileostomy creation during primary surgery were compared with those without ileostomy. Outcomes included length of hospital stay, anastomotic leakage rates and total hospital costs at 1 year.

Results

One hundred and one patients were included in the ileostomy group, and 46 patients were in the non-ileostomy group. The number of female patients was 31 (30.7%) in the ileostomy group and 21 (45.7%) in the non-ileostomy group Mean age was 64.5 ± 11.1 years in the ileostomy group and 62.6 ± 10.7 years in the non-ileostomy group The anastomotic leakage rate was 21.7% in the non-ileostomy group and 15.8% in the ileostomy group (p = 0.385). The grade of leakage and number of anastomotic takedowns did not differ between groups. Mean costs at 1 year after surgery was €26,500.13 in the ileostomy group and €16,852.61 in the non-ileostomy group. The main cost driver was longer total length of hospital stay at 1 year (mean 12.4 ± 13.3 days vs 20.6 ± 12.6 days, p = 0.000).

Conclusions

Morbidity and associated costs after diverting ileostomy are high. The incidence and morbidity of anastomotic leakage was not reduced by creation of an ileostomy. Omission of a diverting ileostomy after TaTME could possibly result in a reduction in treatment associated morbidity and costs.
Literatur
1.
Zurück zum Zitat Borstlap WAA et al (2017) Anastomotic leakage and chronic presacral sinus formation after low anterior resection: results from a large cross-sectional study. Ann Surg 266(5):870–877CrossRef Borstlap WAA et al (2017) Anastomotic leakage and chronic presacral sinus formation after low anterior resection: results from a large cross-sectional study. Ann Surg 266(5):870–877CrossRef
2.
Zurück zum Zitat Penna M et al (2019) Incidence and risk factors for anastomotic failure in 1594 patients treated by transanal total mesorectal excision: results from the international TaTME registry. Ann Surg 269(4):700–711CrossRef Penna M et al (2019) Incidence and risk factors for anastomotic failure in 1594 patients treated by transanal total mesorectal excision: results from the international TaTME registry. Ann Surg 269(4):700–711CrossRef
4.
Zurück zum Zitat Jutesten H et al (2019) High risk of permanent stoma after anastomotic leakage in anterior resection for rectal cancer. Colorectal Dis 21(2):174–182CrossRef Jutesten H et al (2019) High risk of permanent stoma after anastomotic leakage in anterior resection for rectal cancer. Colorectal Dis 21(2):174–182CrossRef
5.
Zurück zum Zitat Midura EF et al (2015) Risk factors and consequences of anastomotic leak after colectomy: a national analysis. Dis Colon Rectum 58(3):333–338CrossRef Midura EF et al (2015) Risk factors and consequences of anastomotic leak after colectomy: a national analysis. Dis Colon Rectum 58(3):333–338CrossRef
6.
Zurück zum Zitat Snijders HS et al (2015) Optimal treatment strategy in rectal cancer surgery: should we be cowboys or chickens? Ann Surg Oncol 22(11):3582–3589CrossRef Snijders HS et al (2015) Optimal treatment strategy in rectal cancer surgery: should we be cowboys or chickens? Ann Surg Oncol 22(11):3582–3589CrossRef
8.
Zurück zum Zitat Emmanuel A et al (2018) Defunctioning stomas result in significantly more short-term complications following low anterior resection for rectal cancer. World J Surg 42(11):3755–3764CrossRef Emmanuel A et al (2018) Defunctioning stomas result in significantly more short-term complications following low anterior resection for rectal cancer. World J Surg 42(11):3755–3764CrossRef
9.
Zurück zum Zitat Ihnat P et al (2016) Diverting ileostomy in laparoscopic rectal cancer surgery: high price of protection. Surg Endosc 30(11):4809–4816CrossRef Ihnat P et al (2016) Diverting ileostomy in laparoscopic rectal cancer surgery: high price of protection. Surg Endosc 30(11):4809–4816CrossRef
11.
Zurück zum Zitat Floodeen H et al (2017) Costs and resource use following defunctioning stoma in low anterior resection for cancer—a long-term analysis of a randomized multicenter trial. Eur J Surg Oncol 43(2):330–336CrossRef Floodeen H et al (2017) Costs and resource use following defunctioning stoma in low anterior resection for cancer—a long-term analysis of a randomized multicenter trial. Eur J Surg Oncol 43(2):330–336CrossRef
12.
Zurück zum Zitat Veltcamp Helbach M et al (2016) Transanal total mesorectal excision for rectal carcinoma: short-term outcomes and experience after 80 cases. Surg Endosc 30(2):464–470CrossRef Veltcamp Helbach M et al (2016) Transanal total mesorectal excision for rectal carcinoma: short-term outcomes and experience after 80 cases. Surg Endosc 30(2):464–470CrossRef
14.
Zurück zum Zitat Moran BJ et al (2014) The English national low rectal cancer development programme: key messages and future perspectives. Colorectal Dis 16(3):173–178CrossRef Moran BJ et al (2014) The English national low rectal cancer development programme: key messages and future perspectives. Colorectal Dis 16(3):173–178CrossRef
15.
Zurück zum Zitat Rahbari NN et al (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147(3):339–351CrossRef Rahbari NN et al (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147(3):339–351CrossRef
16.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRef Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRef
17.
Zurück zum Zitat Matthiessen P et al (2007) Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial. Ann Surg 246(2):207–214CrossRef Matthiessen P et al (2007) Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial. Ann Surg 246(2):207–214CrossRef
18.
Zurück zum Zitat Blok RD et al (2018) Impact of an institutional change from routine to highly selective diversion of a low anastomosis after TME for rectal cancer. Eur J Surg Oncol 44(8):1220–1225CrossRef Blok RD et al (2018) Impact of an institutional change from routine to highly selective diversion of a low anastomosis after TME for rectal cancer. Eur J Surg Oncol 44(8):1220–1225CrossRef
19.
Zurück zum Zitat den Dulk M et al (2007) A multivariate analysis of limiting factors for stoma reversal in patients with rectal cancer entered into the total mesorectal excision (TME) trial: a retrospective study. Lancet Oncol 8(4):297–303CrossRef den Dulk M et al (2007) A multivariate analysis of limiting factors for stoma reversal in patients with rectal cancer entered into the total mesorectal excision (TME) trial: a retrospective study. Lancet Oncol 8(4):297–303CrossRef
20.
Zurück zum Zitat Kim YA et al (2015) Multivariate analysis of risk factors associated with the nonreversal ileostomy following sphincter-preserving surgery for rectal cancer. Ann Coloproctol 31(3):98–102CrossRef Kim YA et al (2015) Multivariate analysis of risk factors associated with the nonreversal ileostomy following sphincter-preserving surgery for rectal cancer. Ann Coloproctol 31(3):98–102CrossRef
21.
Zurück zum Zitat Koperna T (2003) Cost-effectiveness of defunctioning stomas in low anterior resections for rectal cancer: a call for benchmarking. Arch Surg 138(12):1334–8CrossRef Koperna T (2003) Cost-effectiveness of defunctioning stomas in low anterior resections for rectal cancer: a call for benchmarking. Arch Surg 138(12):1334–8CrossRef
22.
Zurück zum Zitat Chapman WC Jr et al (2019) First, do no harm: rethinking routine diversion in sphincter-preserving rectal cancer resection. J Am Coll Surg 228(4):547–556CrossRef Chapman WC Jr et al (2019) First, do no harm: rethinking routine diversion in sphincter-preserving rectal cancer resection. J Am Coll Surg 228(4):547–556CrossRef
23.
Zurück zum Zitat McDermott FD et al (2015) Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks. Br J Surg 102(5):462–479CrossRef McDermott FD et al (2015) Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks. Br J Surg 102(5):462–479CrossRef
24.
Zurück zum Zitat Koedam TWA et al (2018) Transanal total mesorectal excision for rectal cancer: evaluation of the learning curve. Tech Coloproctol 22(4):279–287CrossRef Koedam TWA et al (2018) Transanal total mesorectal excision for rectal cancer: evaluation of the learning curve. Tech Coloproctol 22(4):279–287CrossRef
Metadaten
Titel
Morbidity and costs of diverting ileostomy in transanal total mesorectal excision with primary anastomosis for rectal cancer
verfasst von
J. C. Hol
F. Bakker
N. T. van Heek
G. M. de Jong
F. M. Kruyt
C. Sietses
Publikationsdatum
22.07.2021
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 10/2021
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-021-02498-5

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