Erschienen in:
26.04.2016 | Pictorial Essay
MR imaging features of focal liver lesions in Wilson disease
verfasst von:
Anthony Dohan, Ottavia Vargas, Raphael Dautry, Youcef Guerrache, France Woimant, Lounis Hamzi, Mourad Boudiaf, Aurelia Poujois, Sid Ahmed Faraoun, Philippe Soyer
Erschienen in:
Abdominal Radiology
|
Ausgabe 9/2016
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Abstract
Hepatic involvement in Wilson disease (WD) manifests as a diffuse chronic disease in the majority of patients. However, in a subset of patients focal liver lesions may develop, presenting with a wide range of imaging features. The majority of focal liver lesions in patients with WD are benign nodules, but there are reports that have described malignant liver tumors or dysplastic nodules in these patients. Because of the possibility of malignant transformation of liver nodules, major concerns have been raised with respect to the management and follow-up of patients with WD in whom focal liver lesions have been identified. The assessment of liver involvement in patients with WD is generally performed with ultrasonography. However, ultrasonography conveys limited specificity so that magnetic resonance (MR) imaging is often performed to improve lesion characterization. This review was performed to illustrate the spectrum of MR imaging features of focal liver lesions that develop in patients with WD. It is assumed that familiarity with the MR imaging presentation of focal liver lesions in WD may help clarify the actual nature of hepatic nodules in patients with this condition.