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10.06.2024 | Pelvis

MRI features of ovarian teratomas with somatic-type malignancy and mature cystic teratomas

verfasst von: Takahiko Nakazono, Yutaka Yoshinaga, Ken Yamaguchi, Masatoshi Yokoyama, Keita Kai, Shuichi Fukui, Ryoko Egashira, Kanto Ichinohe, Shigeru Nagaoka, Hiroyuki Irie

Erschienen in: Abdominal Radiology | Ausgabe 10/2024

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Abstract

Purpose

We evaluated the magnetic resonance imaging (MRI) features of ovarian teratomas with somatic-type malignancy (TSMs) and benign ovarian mature cystic teratomas (MCTs) to determine the diagnostic contribution of the MRI findings for differentiating these two teratomas.

Methods

We compared the MRI findings between ovarian TSMs (n = 10) and MCTs (n = 193), and we conducted a receiver operating characteristic (ROC) analysis to determine the MRI findings' contribution to the differentiation of TSMs from MCTs.

Results

The maximum diameters of whole lesion and the largest solid component in the TSMs were larger than those of the MCTs (p = 0.0001 and p < 0.0001, respectively). Fat tissue in solid components was seen in 73/116 (62.9%) MCTs but in none of the TSMs (p = 0.0001). Ring-like enhancement in solid components was seen in 60/116 (51.7%) MCTs and none of the TSMs (p = 0.0031). On dynamic contrast-enhanced MRI (DCE MRI), all of the solid components in the TSMs showed a high- or intermediate-risk time intensity curve (TIC), and those in 113 of the 116 (97.4%) MCTs showed a low-risk TIC (p < 0.0001). The area under the curve of the ROC analysis using the high-/intermediate-risk TIC on DCE MRI was the highest (0.99) for differentiating TSMs from MCTs: sensitivity 100%, specificity 97.4%, positive predictive value 75.0%, negative predictive value 100%, and accuracy, 97.6%.

Conclusion

Compared to ovarian MCTs, ovarian TSMs are larger and have larger solid components with high- or intermediate-risk TICs on DCE MRI. Ovarian MCTs frequently show small solid components with fat tissue, ring-like enhancement, and a low-risk TIC on DCE MRI.

Graphical abstract

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Titel: MRI features of ovarian teratomas with somatic-type malignancy and mature cystic teratomas
verfasst von: Takahiko Nakazono
Yutaka Yoshinaga
Ken Yamaguchi
Masatoshi Yokoyama
Keita Kai
Shuichi Fukui
Ryoko Egashira
Kanto Ichinohe
Shigeru Nagaoka
Hiroyuki Irie
Publikationsdatum: 10.06.2024
Verlag: Springer US
Erschienen in: Abdominal Radiology / Ausgabe 10/2024
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-024-04287-8

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MRI features of ovarian teratomas with somatic-type malignancy and mature cystic teratomas