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Erschienen in: International Ophthalmology 9/2019

06.10.2018 | Photo Essay

Multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection

verfasst von: Chiara Veronese, Chiara Maiolo, Annalisa Gurreri, Mariachiara Morara, Antonio P. Ciardella, Lawrence A. Yannuzzi

Erschienen in: International Ophthalmology | Ausgabe 9/2019

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Abstract

Purpose

To present multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection in a young adult.

Methods

A 49-year-old woman who presented for evaluation of bilateral endogenous candida chorioretinitis underwent complete ophthalmic examination, in addition to fundus photography (FP), enhanced depth imaging optical coherence tomography, fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA).

Results

Multimodal imaging of both eyes of the patient affected by endogenous candida chorioretinitis was performed. FP showed multiple white chorioretinal lesions at the posterior pole, FAF showed dark dot at the posterior pole surrounded by hyperautofluorescence area, FA showed early hyperfluorescence round perifoveal lesion at the posterior pole and small hyperfluorescence dots under the inferior retinal vessels. Early ICGA showed hypofluorescence dots at the posterior pole. Late ICGA showed dark hypofluorescence dots at the posterior pole surrounded by faint hyperautofluorescent ring. OCTA showed dark areas corresponded to hypoperfusion areas seen with early ICGA.

Conclusion

We reported multimodal imaging of an unusual occurrence of multifocal chorioretinitis due to immunosuppression. These findings suggested that the infection resulted from choroidal infiltration via the short posterior ciliary arteries with resultant breakthrough into the retina, rather than via the central retinal artery. By comparing findings on OCTA with data obtained from traditional systems, we are gaining essential information on the pathogenesis of endogenous candida chorioretinitis.
Literatur
1.
Zurück zum Zitat Morinelli EN, Dugel PU, Riffenburgh R, Rao NA (1993) Infectious multifocal choroiditis in patients with acquired immune deficiency syndrome. Ophthalmology 100:1014–1021CrossRefPubMed Morinelli EN, Dugel PU, Riffenburgh R, Rao NA (1993) Infectious multifocal choroiditis in patients with acquired immune deficiency syndrome. Ophthalmology 100:1014–1021CrossRefPubMed
2.
Zurück zum Zitat Invernizzi A, Symes R, Miserocchi E et al (2018) Spectral domain optical coherence tomography findings in endogenous candida endophthalmitis and their clinical relevance. Retina 38:1011–1018CrossRefPubMed Invernizzi A, Symes R, Miserocchi E et al (2018) Spectral domain optical coherence tomography findings in endogenous candida endophthalmitis and their clinical relevance. Retina 38:1011–1018CrossRefPubMed
3.
Zurück zum Zitat Adam MK, Rahimy E (2015) Enhanced depth imaging optical coherence tomography of endogenous fungal chorioretinitis. JAMA Ophthalmol 133(11):e151931CrossRefPubMed Adam MK, Rahimy E (2015) Enhanced depth imaging optical coherence tomography of endogenous fungal chorioretinitis. JAMA Ophthalmol 133(11):e151931CrossRefPubMed
4.
Zurück zum Zitat Lavine JA, Mititelu M (2015) Multimodal imaging of refractory Candida chorioretinitis progressing to endogenous endophthalmitis. J Ophthalmic Inflamm Infect 5:54CrossRefPubMed Lavine JA, Mititelu M (2015) Multimodal imaging of refractory Candida chorioretinitis progressing to endogenous endophthalmitis. J Ophthalmic Inflamm Infect 5:54CrossRefPubMed
5.
Zurück zum Zitat Stephens JD, Adam MK, Todorich B et al (2017) Optical coherence tomography findings in endogenous fungal chorioretinitis, retinitis, and endophthalmitis. Ophthalmic Surg Lasers Imaging Retina 1(48):894–901CrossRef Stephens JD, Adam MK, Todorich B et al (2017) Optical coherence tomography findings in endogenous fungal chorioretinitis, retinitis, and endophthalmitis. Ophthalmic Surg Lasers Imaging Retina 1(48):894–901CrossRef
Metadaten
Titel
Multimodal imaging of multifocal chorioretinitis secondary to endogenous candida infection
verfasst von
Chiara Veronese
Chiara Maiolo
Annalisa Gurreri
Mariachiara Morara
Antonio P. Ciardella
Lawrence A. Yannuzzi
Publikationsdatum
06.10.2018
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 9/2019
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-018-1025-9

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