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2016 | OriginalPaper | Buchkapitel

5. Multiphotonentomographie

verfasst von : Michael Zieger, Dr. rer. nat., Steffen Springer, Martin Johannes Koehler, Dr. med., Martin Kaatz, PD Dr. med. habil.

Erschienen in: Nichtinvasive physikalische Diagnostik in der Dermatologie

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Die Multiphotonentomographie (MPT) hat in den letzten Jahren eine zunehmende Bedeutung als nichtinvasive Untersuchungsmethode in der Dermatologie erfahren. Durch die MPT wird eine „optische Biopsie“ bis zu einer Tiefe von 200 μm ermöglicht, die zelluläre und extrazelluläre Strukturen mit subzellulärer Auflösung darstellt. Mit der MPT ist eine Charakterisierung der Zellmorphologie und des dermalen Fasernetzwerkes ohne zusätzliche Fluoreszenzmarkierung der Gewebe in vivo möglich. Das Verfahren wird gegenwärtig noch vor allem in der biomedizinischen Forschung, zunehmend aber auch in der klinischen Diagnostik eingesetzt. Dabei ist die morphologische Beurteilung von Tumoren der Haut (Basalzellkarzinom, Plattenepithelkarzinom, malignes Melanom), bei entzündlichen und allergischen Dermatosen sowie beim Nachweis transkutaner Transportprozesse möglich. Darüber hinaus können funktionelle und metabolische Prozesse von Zellen, Zellverbänden und Geweben untersucht werden.

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Titel: Multiphotonentomographie
verfasst von: Michael Zieger, Dr. rer. nat.
Steffen Springer
Martin Johannes Koehler, Dr. med.
Martin Kaatz, PD Dr. med. habil.
Verlag: Springer Berlin Heidelberg
Buch: Nichtinvasive physikalische Diagnostik in der Dermatologie
Print ISBN: 978-3-662-46388-8

Electronic ISBN: 978-3-662-46389-5

Copyright-Jahr: 2016
DOI: https://doi.org/10.1007/978-3-662-46389-5_5

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5. Multiphotonentomographie

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Leitlinien kompakt für die Dermatologie

Neu im Fachgebiet Dermatologie

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Kein Abstrich bei chronischen Wunden ohne Entzündungszeichen!

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“

Vitiligo: Prävalenz steigt und viele Erkrankte werden spät behandelt

Update Dermatologie