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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report

Zeitschrift:
Journal of Medical Case Reports > Ausgabe 1/2011
Autoren:
Shannon Fogh, Charles Glass, David W Andrews, Maria Werner-Wasik
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-5-183) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

SF participated in the design and drafted the manuscript. CG participated in the design and collection of the information. DA participated in the design and helped to draft the manuscript and MW-W participated in the design and edited the manuscript. All authors have read and approved the final manuscript.

Abstract

Introduction

High grade gliomas are an insidious disease associated with an extremely poor prognosis. The role of re-irradiation for recurrent gliomas is unclear but several retrospective studies have indicated mild toxicity and modest outcomes with this regimen. With subsequent progression, it is unclear what options remain and more radiotherapy is rarely offered for fear of surpassing normal central nervous system tissue tolerance and causing significant side effects without significant benefit.

Case presentation

In this report, we describe a 37-year-old Caucasian male initially diagnosed with a grade IV oligodendroglioma, who received multiple courses of re-irradiation and experienced a survival of 10 years with minimal cognitive or neurologic deficits.

Conclusion

Significant toxicity with multiple courses of radiation does not always occur. Re-irradiation should be considered in a salvage setting.

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