Multiple Desmoplastic Cellular Neurothekeomas in Child: Report of the First Oral Case and Review of the Literature
- 08.06.2017
- Original Paper
Erschienen in:
- Verfasst von
- Tatiana Fernandes Araújo Almeida
- Flaviana Dornela Verli
- Cássio Roberto Rocha dos Santos
- Saulo Gabriel Moreira Falci
- Luciana Yamamoto Almeida
- Lana Kei Yamamoto Almeida
- Ana Terezinha Marques Mesquita
- Jorge Esquiche León
- Erschienen in
- Head and Neck Pathology | Ausgabe 1/2018
Abstract
Cellular neurothekeomas (CNs) are distinctive benign tumors of uncertain histogenesis, with predilection for the skin of the head and neck region. We describe the first case of multiple desmoplastic CNs (DCNs) affecting the oral cavity in a 9-year-old girl. Histopathologic evaluation showed a proliferation of spindle and epithelioid cells, forming nests and bundles, supported by exuberant fibrous stroma, as well as scattered multinucleated floret-like giant cells. The tumor cells were immunopositive for vimentin, CD63, CD56, whereas AE1/AE3, S100, CD34, α-SMA, GFAP, EMA, CD57 and NSE were negative. Ki-67 was <2%. Multiple DCNs should be considered in the differential diagnosis of oral nodular lesions.
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- Titel
- Multiple Desmoplastic Cellular Neurothekeomas in Child: Report of the First Oral Case and Review of the Literature
- Verfasst von
-
Tatiana Fernandes Araújo Almeida
Flaviana Dornela Verli
Cássio Roberto Rocha dos Santos
Saulo Gabriel Moreira Falci
Luciana Yamamoto Almeida
Lana Kei Yamamoto Almeida
Ana Terezinha Marques Mesquita
Jorge Esquiche León
- Publikationsdatum
- 08.06.2017
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 1/2018
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-017-0828-8
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