Glomus tumor is a rare benign tumor that most frequently occurs in the glomus body in the subungual regions of digits [
8]. The typically cell components were glomus cells, vasculature, and smooth muscle cells [
9]. Within the glomus tumor family, the glomus tumor itself consists predominantly of glomus cells. The glomangioma shows high density of vascularity [
10] and the glomangiomyoma shows elongated smooth muscle cells in pathological manifestation [
11]. The clinical diagnosis of glomus tumor is made based on examination. Typical symptoms of a glomus tumor are localized pain and cold sensitivity [
12]. An intraneural glomus tumor of the digital nerve may cause numbness and tingling, cold insensitivity, paresthesia, a positive Tinel’s sign, or no neurological deficits [
1‐
4,
7]. Although the number of cases is small, it is evident that the symptoms of a glomus tumor are similar to those of a neuroma, and thus, it is difficult to make a definite diagnosis by physical examination alone. Because of the presence of numbness and a positive Tinel’s sign, the present case was initially diagnosed as a neuroma. Pacinian corpuscles neuroma was pain and swelling tumor in finger with or without history of trauma, subcutaneous plane, spherical, gray and in clusters lesions can be observed in pathological study [
13]. Giant cell tumor of tendon sheath is a common benign with incentives, multiple nodules tumor arising in the tendon sheath. In treatment, the elimination of the tumor lesions including soft tissue and bone is favored. Synovial cells and a few multinucleated giant cells can be observed in pathological study [
14]. Enchondroma was the most common benign tumour of the tubular bones in hands. The treatment was usually surgery [
15].MRI is an effective tool to identify finger masses [
14,
15]. In the present case, although MRI findings suggested that the tumor originated from the nerve, the significant increase in the signal after contrast enhancement was not consistent with the imaging features of a neuroma. However, the presence of multiple intraneural glomus tumors has not been previously reported; furthermore, the tumor may be too small. Thus, the intraoperative exploration must be thorough. A biopsy was not conducted in order to avoid bleeding owing to the proximity of the tumor to the proper palmar digital artery.
A surgical procedure was conducted to remove the tumor completely. Some intraneural glomus tumors cannot be detached from the nerve fascicle and can only be removed along with some segment of the nerve fascicle, which can cause nerve defects. The use of nerve grafts for treatment of digital nerve defects results in greater losses in the donor sites [
16]. If an intraneural glomus tumor is clinically suspected, a relevant examination, such as MRI, must be performed as early as possible to enable early diagnosis and save the nerve fascicle. In the present case, one nerve fascicle could be preserved, and thus, recovery of nerve function after surgery is expected to be ideal. The patient fully recovered sensation in his fingertip at 6 months after surgery. Intraneural glomus tumor must be added to the differential diagnosis of neurogenic tumors. Early diagnosis can enable the retention of neurological function.