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Erschienen in: Current Cardiology Reports 7/2016

01.07.2016 | Invasive Electrophysiology and Pacing (EK Heist, Section Editor)

Multisite Pacing for Cardiac Resynchronization Therapy: Promise and Pitfalls

verfasst von: Antonios P. Antoniadis, Jonathan M. Behar, Simon Claridge, Tom Jackson, Manav Sohal, Christopher Aldo Rinaldi

Erschienen in: Current Cardiology Reports | Ausgabe 7/2016

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Abstract

Cardiac resynchronization therapy (CRT) reduces the morbidity and mortality of patients with symptomatic heart failure and intraventricular conduction delay. However, its clinical outcomes are non-uniform and up to one third of treated patients are subsequently classified as non-responders. Multisite pacing (MSP), i.e. stimulating the myocardium from multiple locations, has emerged as a potential therapeutic option in patients requiring CRT. The rationale for MSP is based on the hypothesis that increasing the pacing locations in the left ventricle results in a more physiologic and coordinated myocardial systole. MSP can be achieved by additional leads in the right or left ventricle but this can lead to high battery drain and more frequent generator replacements. Multipolar left ventricular leads can deliver pacing at multiple sites, and therefore, a single lead can be used for MSP. However, the optimal programming settings and the outcomes of this approach remain yet to be determined.
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Metadaten
Titel
Multisite Pacing for Cardiac Resynchronization Therapy: Promise and Pitfalls
verfasst von
Antonios P. Antoniadis
Jonathan M. Behar
Simon Claridge
Tom Jackson
Manav Sohal
Christopher Aldo Rinaldi
Publikationsdatum
01.07.2016
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 7/2016
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-016-0741-x

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