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Clinical Rheumatology

Erschienen in:

16.06.2020 | Review Article

Multisystemic manifestations of IgA vasculitis

verfasst von: Lina Du, Panpan Wang, Chang Liu, Shaojing Li, Shuang Yue, Yan Yang

Erschienen in: Clinical Rheumatology | Ausgabe 1/2021

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Abstract

Immunoglobulin A vasculitis (IgAV), also known as Henoch-Schönlein Purpura, is one of the most common kind of systemic vasculitis in children, and due to the involvement of small blood vessels throughout the body, this disease can cause a variety of symptoms in different organs. Our aim was to review the data on various systemic manifestations of IgAV. A research of the literature was performed in PubMed database, utilizing the MeSH terms “IgA vasculitis” and “Henoch Schönlein Purpura”. According to the predetermined structure of the manuscript, we extracted and sorted out the relevant data. Clinically, almost all the patients will present with palpable skin purpura, together with arthritis, gastrointestinal tract involvement, or kidney damage. Other rare systemic manifestations include neurological symptoms, scrotal involvement, and cardiopulmonary disease. When uncommon complications occur, patients may be misdiagnosed as other diseases, thus delaying treatment. Although the course of IgAV is mostly self-limited, misdiagnosis can also lead to a poor prognosis. A comprehensive awareness to the clinical manifestations of IgAV is the necessary prerequisite for its timely diagnosis. Prompt diagnosis and adequate treatment are essential for optimal results.

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Titel: Multisystemic manifestations of IgA vasculitis
verfasst von: Lina Du
Panpan Wang
Chang Liu
Shaojing Li
Shuang Yue
Yan Yang
Publikationsdatum: 16.06.2020
Verlag: Springer International Publishing
Erschienen in: Clinical Rheumatology / Ausgabe 1/2021
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-020-05166-5

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