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Erschienen in: Pediatric Cardiology 6/2011

01.08.2011 | Original Article

Myocardial Perfusion and Exercise Capacity 12 Years After Arterial Switch Surgery for D-Transposition of the Great Arteries

verfasst von: Lauren E. Sterrett, Marcus S. Schamberger, Eric S. Ebenroth, Aslam R. Siddiqui, Roger A. Hurwitz

Erschienen in: Pediatric Cardiology | Ausgabe 6/2011

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Abstract

Peak exercise myocardial perfusion was evaluated in patients with D-transposition of the great arteries 12 years after the arterial switch operation (SWITCH) to evaluate coronary perfusion. Gas-exchange measurements were used to assess cardiac limiting factors to exercise capacity in SWITCH patients when compared to healthy gender-matched controls (CON). Peak myocardial perfusion was evaluated in 42 patients 12 years post-SWITCH, using technetium-99 m (Tetrofosmin). SWITCH exercise data was compared to 42 gender-matched controls (CON). One symptomatic and one asymptomatic SWITCH patient had abnormal exercise myocardial perfusion; both patients had variant coronary anatomy preoperatively. SWITCH patients had lower VO2peak (p < 0.01), peak heart rates (p = 0.01), percentages of age-predicted peak heart rates (p < 0.01), and peak oxygen pulses indexed to body surface area (p < 0.01) than CON patients. Exercise testing with myocardial perfusion imaging helped to identify the rare SWITCH patient with coronary insufficiencies. This study demonstrates that exercise testing with myocardial perfusion scans can help identify patients at risk for myocardial events. This study also demonstrated that SWITCH patients have a mildly diminished VO2peak when compared to CON patients.
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Metadaten
Titel
Myocardial Perfusion and Exercise Capacity 12 Years After Arterial Switch Surgery for D-Transposition of the Great Arteries
verfasst von
Lauren E. Sterrett
Marcus S. Schamberger
Eric S. Ebenroth
Aslam R. Siddiqui
Roger A. Hurwitz
Publikationsdatum
01.08.2011
Verlag
Springer-Verlag
Erschienen in
Pediatric Cardiology / Ausgabe 6/2011
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-011-9975-y

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