Erschienen in:
01.10.2011 | Case Report
Myxoid malignant fibrous histiocytoma of the ovary: a case report
verfasst von:
Seung-Yeon Choi, Tae-Hyun Kim, Hwang-Shin Park, Chang-Ohk Sung, Jeong-Won Lee, Sang Yong Song, Byoung-Gie Kim, Duk-Soo Bae
Erschienen in:
International Journal of Clinical Oncology
|
Ausgabe 5/2011
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Abstract
A 46-year-old woman presented with whole abdominal discomfort, and imaging revealed a 3-cm-sized ill-defined ovarian mass with extensive peritoneal carcinomatosis. Histologic examination showed malignant fibrous histiocytoma of ovary with predominant myxoid stroma. Microscopic examination showed a highly cellular neoplasm composed of fibroblast-like cells with a predominant myxoid stroma and high pleomorphism and mitotic activity. Immunohistochemically, the tumor was negative for smooth muscle actin, desmin, S-100, pancytokeratin, c-kit, epithelial membrane antigen, and calretinin. Malignant fibrous histiocytoma of ovary is extremely rare, with only six previously reported cases. To the best of our knowledge, the myxoid type of malignant fibrous histiocytoma of ovary has not been previously reported in the English literature except for a case arising in a dermoid cyst of ovary. We present the case and briefly discuss the differential diagnosis.