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Erschienen in: Allergo Journal 3/2022

09.05.2022 | Allergologie in der HNO-Heilkunde | Übersicht

White Paper Erdnussallergie - Teil 4: Management und Therapie der Erdnussallergie

verfasst von: PD Dr. Katharina Blümchen, Anna Fischl, Thomas Eiwegger, Eckard Hamelmann, Ludger Klimek, Lars Lange, Zsolt Szepfalusi, Christian Vogelberg, Kirsten Beyer

Erschienen in: Allergo Journal | Ausgabe 3/2022

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Zusammenfassung

Das bisherige Management einer IgE-vermittelten primären Erdnussallergie besteht aus den beiden Grundsäulen "Expositionsprophylaxe" mit Meidung des Allergens sowie "Notfalltherapie" mit kurzfristiger Behandlung einer akuten allergischen Reaktion nach akzidenteller Ingestion. Akzidentelle Reaktionen sind trotz versuchter Meidung häufig. Der Schweregrad einer allergischen oder auch anaphylaktischen Reaktion nach akzidentellem Genuss ist zuvor schwer abschätzbar. Zudem können Reaktionsschwellen je nach begleitendem Augmentationsfaktor schwanken. Daher sollte jeder Erdnussallergiker eine individuelle Ernährungsberatung sowie eine Einweisung in das Notfallset und gegebenenfalls eine Anaphylaxieschulung erhalten. Seit Herbst 2021 steht mit einem Medikament zur oralen Immuntherapie (OIT) nun erstmals eine kausale Behandlungsmöglichkeit für vier- bis 17-jährige erdnussallergische Kinder und Jugendliche zur Verfügung. Die OIT mit Erdnussprotein als entfettetes Pulver von Arachis hypogaea, semen (Erdnüsse) führt zu einer Desensibilisierung mit einer guten Wirksamkeit und einem akzeptablen Sicherheitsprofil. Weitere Behandlungsoptionen mit unterschiedlichen Therapieansätzen befinden sich ebenfalls in der Entwicklung und werden in den kommenden Jahren wahrscheinlich das Therapieangebot erweitern.
Zitierweise: Blumchen K, Fischl A, Eiwegger T, Hamelmann E, Klimek L, Lange L, Szepfalusi Z, Vogelberg C, Beyer K. White paper peanut allergy - part 3: Management and therapy of peanut allergy. Allergo J Int 2022;31:69-80
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Metadaten
Titel
White Paper Erdnussallergie - Teil 4: Management und Therapie der Erdnussallergie
verfasst von
PD Dr. Katharina Blümchen
Anna Fischl
Thomas Eiwegger
Eckard Hamelmann
Ludger Klimek
Lars Lange
Zsolt Szepfalusi
Christian Vogelberg
Kirsten Beyer
Publikationsdatum
09.05.2022
Verlag
Springer Medizin
Erschienen in
Allergo Journal / Ausgabe 3/2022
Print ISSN: 0941-8849
Elektronische ISSN: 2195-6405
DOI
https://doi.org/10.1007/s15007-022-5005-z

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