Skip to main content
Erschienen in: Journal of Assisted Reproduction and Genetics 5/2018

30.05.2018 | Editor's Commentary

Naturing and nurturing the competent oocyte: it’s all in the niche

verfasst von: David F. Albertini

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 5/2018

Einloggen, um Zugang zu erhalten

Excerpt

Despite claims to the contrary, and the currency it carries in human ARTs, harvesting more eggs in the course of infertility treatment is not necessarily a good thing when it comes to truly meaningful outcomes. The “more is better” mentality may have been successfully circumvented in the case of azoospermia, but not so for Mother Nature’s design for monovular species like ourselves. The challenge in human ARTs of obtaining oocytes of the competent variety remains alive and well if any hope of generating embryos obtains for transfers resulting in a term (or near-term) pregnancy. …
Literatur
1.
Zurück zum Zitat Swain JE, Pool TB. ART failure: oocyte contributions to unsuccessful fertilization. Hum Reprod Update. 2008;14(5):431–46.CrossRefPubMed Swain JE, Pool TB. ART failure: oocyte contributions to unsuccessful fertilization. Hum Reprod Update. 2008;14(5):431–46.CrossRefPubMed
2.
Zurück zum Zitat Conti M, Franciosi F. Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events. Hum Reprod Update. 2018;24(3):245–66.CrossRefPubMed Conti M, Franciosi F. Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events. Hum Reprod Update. 2018;24(3):245–66.CrossRefPubMed
3.
Zurück zum Zitat Bouckenheimer J, Fauque P, Lecellier CH, Bruno C, Commes T, Lemaitre JM, et al. Differential long non-coding RNA expression profiles in human oocytes and cumulus cells. Sci Rep. 2018;8(1):2202.CrossRefPubMedPubMedCentral Bouckenheimer J, Fauque P, Lecellier CH, Bruno C, Commes T, Lemaitre JM, et al. Differential long non-coding RNA expression profiles in human oocytes and cumulus cells. Sci Rep. 2018;8(1):2202.CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Ernst EH, Franks S, Hardy K, Villesen P, Lykke-Hartmann K. Granulosa cells from human primordial and primary follicles show differential global gene expression profiles. Hum Reprod. 2018;33(4):666–79.CrossRefPubMed Ernst EH, Franks S, Hardy K, Villesen P, Lykke-Hartmann K. Granulosa cells from human primordial and primary follicles show differential global gene expression profiles. Hum Reprod. 2018;33(4):666–79.CrossRefPubMed
5.
Zurück zum Zitat Sanchez F, Lolicato F, Romero S, De Vos M, Van Ranst H, Verheyen G, et al. An improved IVM method for cumulus-oocyte complexes from small follicles in polycystic ovary syndrome patients enhances oocyte competence and embryo yield. Hum Reprod. 2017;32(10):2056–68.CrossRefPubMed Sanchez F, Lolicato F, Romero S, De Vos M, Van Ranst H, Verheyen G, et al. An improved IVM method for cumulus-oocyte complexes from small follicles in polycystic ovary syndrome patients enhances oocyte competence and embryo yield. Hum Reprod. 2017;32(10):2056–68.CrossRefPubMed
6.
Zurück zum Zitat Russell DL, Gilchrist RB, Brown HM, Thompson JG. Bidirectional communication between cumulus cells and the oocyte: Old hands and new players? Theriogenology. 2016;86(1):62–8.CrossRefPubMed Russell DL, Gilchrist RB, Brown HM, Thompson JG. Bidirectional communication between cumulus cells and the oocyte: Old hands and new players? Theriogenology. 2016;86(1):62–8.CrossRefPubMed
7.
Zurück zum Zitat Shapiro JA. Living Organisms Author Their Read-Write Genomes in Evolution. Biology (Basel). 2017;6(4):1–76. Shapiro JA. Living Organisms Author Their Read-Write Genomes in Evolution. Biology (Basel). 2017;6(4):1–76.
Metadaten
Titel
Naturing and nurturing the competent oocyte: it’s all in the niche
verfasst von
David F. Albertini
Publikationsdatum
30.05.2018
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 5/2018
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-018-1220-7

Weitere Artikel der Ausgabe 5/2018

Journal of Assisted Reproduction and Genetics 5/2018 Zur Ausgabe

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.