Ausgabe 12/2025
Inhalt (107 Artikel)
Exploiting the cardioprotective potential of metformin against cardiotoxic agents
- Review
Ahmad Safari Maleki, A. Wallace Hayes, Gholamreza Karimi
Pathophysiology, conventional treatments, and evidence-based herbal remedies of hair loss with a systematic review of controlled clinical trials
- Open Access
- Review
Anood T. Allam, Riham A. El-Shiekh, Ahmed M. El-Dessouki, Noha M. Gamil, Nehal Mohamed Eisa, Menna M. Ayoub, Weam A. M. Khallil, Mariam A. N. Farag, Madonna G. Attallah, Mohamed S. Abd E. L. Hafeez, Dina Abou-Hussein
Balancing efficacy and hepatotoxicity: a comprehensive review of oral medications in psoriasis management
- Open Access
- Review
Alaa E. Elsisi, Sally El-Sayed Abu-Risha, Mahmoud Abdelrahman Alkabbani, Laila A. Ramadan, Samia Salem Sokar
Morin: a promising hepatoprotective agent against drug and chemical-induced liver injury
- Review
Anandakumar Pandi, Nabendu Sen, Vanitha Manickam Kalappan, Vanita Lal
Efficacy and safety of calcium channel blockers in migraine management; a systematic review
- Review
Hamed Ghiami, Mohammadsalman Parsapour, Sahba Khalilzadeh, Hanieh Rahmani, Navid Omidkhoda, Omid Arasteh
Innovative horizons: harnessing drug repositioning for targeted therapeutics in colorectal cancer
- Review
Mojtaba Tarin, Mahsa Akbari Oryani, Fatemeh Attarian, Seyedeh Sara Sajjadi, Ali Mehri, Mehdi Karimi-Shahri
Targeting CAF-specific metabolic pathways in breast cancer
- Review
Alaa Khalaf Bediwi, Ahmed Hjazi, Mundher Kedhem, Ali G. Alkhathami, RenukaJyothi S., Priya Priyadarshini Nayak, Amrita Pargaien, Udaybir Singh, Fathi Jihad Hammady, Salah Abdulhadi Salih
Mechanisms underlying methamphetamine-induced disruption of testicular integrity
- Review
Florence Bukola Adisa, Mega Obukohwo Oyovwi, Ayodeji Folorunsho Ajayi
NRF2 as a ferroptosis gatekeeper in colorectal cancer: implications for therapy
- Review
Amr Ali Mohamed Abdelgawwad El-Sehrawy, Abdulla A. Al-dulaimi, Ali G. Alkhathami, Renuka Jyothi S, Rajashree Panigrahi, Amrita Pargaien, Udaybir Singh, Ahmed Husseini, Mohammed Jawad Alnajar
Protamine sulphate for heparin reversal in percutaneous cardiac interventions: a systematic review and meta-analysis of randomized controlled trials
- Open Access
- Review
Elsayed Balbaa, Ahmed Farid Gadelmawla, Abdelrahman M. Tawfik, Ahmed Naeem, Ahmed Elbataa, Mohammad Bazzazeh, Ahmed Ramadan Fatiem, Khaled Ali, Obieda Altobaishat, Mohamed Abuelazm
Effectiveness and safety of perampanel in Lennox-Gastaut syndrome: a GRADE-assessed systematic review and meta-analysis
- Review
Danisha Kumar, Haneen Sabet, Amr Elshahat, Mohamed El-Moslemani, Abdelfattah Arafa, Mahmoud G. A. Saleh, Sama Mahmoud Gamal, Abdallah Abbas
The long antisense non-coding RNA HOXA transcript at the distal tip (LncRNA HOTTIP) in health and disease: a comprehensive review and in silico analysis
- Open Access
- Review
Mona G. El-Sisi, Sara M. Radwan, Sameh S. Ali, Mohamed Y. Mostafa, Nadia M. Hamdy
Ferroptosis rewired: ncRNA gatekeepers as pharmacological targets in hepatocellular carcinoma
- Review
Abdulrahman T. Ahmed, Mahmood Jawad, Gaurav Sanghvi, Roopashree R., Aditya Kashyap, Hussein Riyadh Abdul Kareem Al-Hetty, S. Gayathri, Rajashree Panigrahi, Yasser Fakri Mustafa, Wael Dheaa Kadhim
Exosomal peptides and proteins in wound healing and skin regeneration
- Review
Sejal Porwal, Rishabha Malviya, Musarrat Husain Warsi, Ameeduzzafar Zafar, Mohammad Khalid, Omar Awad Alsaidan, Sathvik Belagodu Sridhar, Javedh Shareef, Tarun Wadhwa
Enhancing cancer treatment with marine algae–derived bioactive chemicals: a review
- Review
B. Parveen, Narayanan Mathiyazhagan
LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology
- Review
Saade Abdalkareem Jasim, Harikumar Pallathadka, Ahmed Hjazi, Gaurav Sanghvi, Rekha M M, Mohit Agarwal, Renu Arya, Mohammed qasim alasheqi, Abed J. Kadhim, Muthena kariem
Cognitive impairment and risk of dementia in heart failure: the exuberating role of digoxin
- Review
Hayder M. Al-kuraishy, Esraa H. Fahad, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Majid S. Jabir, Ali I. Al-Gareeb, Ali K. Albuhadily
Cells, tissues, and vigilance: navigating the complex landscape of biovigilance in India
- Review
Raihana Nilofar A, Deva Reka, Rajendran Priyadharsini
The therapeutic effects of Plantago major and its main constituents on respiratory diseases: a narrative review
- Review
Seyyed Javad Boskabadi, Fatemeh Farzameh, Kousar Mohammadnejad, Mohammad Hossein Boskabady
Harnessing organoid technology to model autoimmune pathways in rheumatological and inflammatory disorders
- Review
Amr Ali Mohamed Abdelgawwad El-Sehrawy, Teeba Ammar Rashid, Paul Rodrigues, Baneen C. Gabaal, Suhas Ballal, Abhayveer Singh, T. KRITHIGA, Mehul Manu, N. Esanmurodova, Jamal K. Abbas
Lipid-based nanocarriers in combination chemotherapy: a promising strategy for advanced skin cancer management
- Review
Jyotiraditya Mall, Md Faheem Haider, Nazish Naseem, Md Azizur Rahman, Irfan Ahmad
Efficacy and safety of sotatercept in pulmonary arterial hypertension: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
- Review
Laila Shalabi, Shehroze Tabassum, Bashar M. Al Zoubi, Hosam I. Taha, Ibrahim Gowaily, Mohamed Abuelazm
PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells
- Open Access
- Review
Kirti S. Prabhu, Shilpa Kuttikrishnan, Zahwa Mariyam, Ummu Habeeba, Anu Jayanthi Panicker, Tariq Masoodi, Kulsoom Junejo, Shahab Uddin
Harnessing IDO inhibitors to optimize cancer immunotherapy
- Review
Safia Obaidur Rab, Huda K. Jaafar, Majid S. Jabir, H. Malathi, Seema Devi, Atreyi Pramanik, Hussein Riyadh Abdul Kareem Al-Hetty, Mohammed Jawad Alnajar, Sabrean F. Jawad, Yasser Fakri Mustafa
Natural products proposed for the management of Huntington’s disease (HD): a comprehensive review
- Open Access
- Review
Aya Salman, Aya H. Eid, Samar S. Khalaf, Ahmed M. El-Dessouki, Riham A. El-Shiekh, Shaza H. Aly
Unlocking the role of tRNA-derived fragments in shaping breast cancer signaling
- Review
Chou-Yi Hsu, Saade Abdalkareem Jasim, Renuka S. Jyothi, Irfan Ahmad, Ahmed Hjazi, Mahmood Hasen Shuhata Alubiady, Aashna Sinha, Yasser Fakri Mustafa, Ahmed Muzahem Al-Ani, Ahmed Hussn
Modulating depression through the gut–brain axis: the role of gut microbiota in therapeutic interventions
- Review
Muhammad Muzammil Nazir, Warisha Ghaffar, Ghanva Mustafa, Saira Saeed, Muhammad Umar Ijaz, Asma Ashraf
Molecular insight into the therapeutic potential of miR-34a in retinoblastoma
- Review
Pouya Goleij, Mohammad Amin Khazeei Tabari, Aryan Rezaee, Pantea Majma Sanaye, Ali Kheirandish, Khalaf F. Alsharif, Maria Daglia, Danaé S. Larsen, Haroon Khan, Mohadeseh Poudineh
Molecular regulation by ubiquitin-specific proteases (USPs) in HCC: cell cycle, oncogenic signaling, and beyond
- Review
Furqan N. Al-Khateeb, Asraa Yacoob Yousif, Sarmad Ghazi Al-Shawi, Ali G. Alkhathami, Roopashree R., Aditya Kashyap, Deepak Nathiya, Subhashree Ray, Mohammed Jawad Alnajar, Muthana Kareem
A review of the extraction technologies, structural characterization, chemical modification, and pharmacological effects of Ganoderma lucidum polysaccharides
- Review
ChenXue Li, RuoBing Zhang, Bing Tian, Bing Liu, Yu Mei, WenLan Li
Mechanistic insights into postbiotics as therapeutic agents in type 2 diabetes management
- Review
Negar Ebadpour, Navid Faraji, Mohammad Abavisani, Sercan Karav, Amirhossein Sahebkar
Unravelling chemotherapeutic activity of fisetin ruthenium-p-cymene complex in lung cancer treatment by the modulation of GRB2/RAS/MEK/DNMT1 signaling pathway
- Research
Ishita Seal, Sakuntala Gayen, Sidhanta Sil, Abhijit Das, Souvik Roy
Progesterone- and deoxycorticosterone-derived GABAergic neurosteroids induce itch-related scratching behavior in mouse model of atopic dermatitis
- Open Access
- Research
Rina Tanaka, Satoshi Tanaka, Masanori Fujii
Chitosan gold nanogel containing Rova-Typhoid immunotoxins against the DLL3 receptor has a promising effect on small-cell lung cancer
- Research
Ali Rajabi, MohammadHossein Ataee, Hamideh Mahmodzadeh Hosseini, Jafar Amani
Effects of disease severity-based nursing intervention on immune function and IFN-γ, IL-6, and TNF-α for children with IgA vasculitis nephritis
- Research
Xi Zhang, Xiang Li, Ying Hu
Quercetin-loaded zinc oxide nanoparticles encapsulated in chitosan-alginate: a synergistic approach to cancer and bacterial therapy
- Research
Noorolhoda Khalighi, Somayeh Reiisi, Azam Mokhtari, Razieh Heidari, Masoud Ghorbanpoor
Suppressive effect of topical moxifloxacin on imiquimod-induced model of psoriasis in mice
- Research
Alaa Hamza Abbas, Muayad Sraibet Abbood, Hayder Ridha-Salman, Salar Ayad Fakhri, Zahraa Hamza Abbas, Ali Jihad Hemid Al-Athari
Fenofibrate attenuates doxorubicin-induced cardiotoxicity in patients with breast cancer: a randomized controlled trial
- Open Access
- Research
Hagar K. Dewidar, Amr A. Ghannam, Tarek M. Mostafa
Induction of potent preferential cell death, severe DNA damage and p53-independent ROS-mediated mitochondrial apoptosis by CaTiO3NPs in HNO-97 tongue cancer cells
- Open Access
- Research
Hanan R. H. Mohamed, Maivel Michael, Yusuf Elberry, Hagar Magdy, Maryam Ismail, Nourhan Eltayeb, Gehan Safwat, Ayman Diab
Modulating platelet-activating factor by rupatadine attenuates gentamicin-induced nephrotoxicity in rats via NF-κB/caspase-3 and Nrf2/HO-1 signaling cascades
- Open Access
- Research
Reham H. Mohyeldin, Mahmoud Abdelnaser, Ehab E. Sharata, Al Shaimaa Mahmoud Kotb, Fatma F. Ali, Mina Ezzat Attya, Heba M. Tawfik, Mahmoud A. Elrehany, Remon Roshdy Rofaeil
Contractile effects of retatrutide in isolated mouse atrial preparations
- Open Access
- Research
Joachim Neumann, Undine Ahlrep, Britt Hofmann, Ulrich Gergs
Gastrodin inhibits hexokinase-2 mediated glycolysis to rescue rotenone-damaged PC12 cells
- Research
Min Chen, Jiaming Tian, Buyun Jia, Meng Wang, Anqi Han, Jiming Zhu, Shasha Tian, Xiaoming Gao, Baikun Li, Qinglin Li, Shanshan Li
Repurposing liraglutide to the management of DSS-induced colitis: a potential for promoting autophagy
- Open Access
- Research
Ahmed Atef Saadoun, Alia Hamed Abdelsattar, Amro Hatem Elsaid, Eslam Abdelaziz Abdelaleam, Hazem Khaled Abdelkader, Hend Mohamed Ibrahim, Merna Sabri Saad, Moumen Said Ellawi, Rana Elshahawi Elsaid, Aya Maghrabia, Dina Ibrahim, Nehal M. Ramadan
Protective effects of licofelone on experimental skin flap survival rat model via cyclooxygenase and lipoxygenase inhibition: involvement of inflammatory cytokines and nitric oxide
- Research
Mahla Masoumi, Saba Ahmadi, Razieh Mohammad Jafari, Mohammad Amin Manavi, Seyed Mohammad Tavangar, Ahmad Reza Dehpour
Changes in nationwide thyroid hormone replacement use during the pandemic: results from the Trends in Drug Utilization During COVID-19 Pandemic in Turkey (PANDUTI-TR) Study
- Open Access
- Research
Caner Vizdiklar, Volkan Aydin, Onur Gultekin, Gokhan Tazegul, Ahmet Akici
Targeting inflammatory dysregulation in metabolic dysfunction-associated steatotic liver disease rat model: the preventive and therapeutic effects of acetyl-11-keto-beta-boswellic acid
- Research
Sajad Ehtiati, Roya Pakrad, Seyyed Hossein Khatami, Reza Ataei Kachouei, Alireza Doagoo, Hossein Lanjanian, Seyyed Amir Hossein Ghazizadeh Hashemi, Nastaran Hamed, Behzad Hatami, Reyhane Ahmadzade, Farzaneh Salmani, Saeed Karima
Stemness reducible effects of glyasperin A against NCCIT teratocarcinomas
- Research
Thi Nga Nguyen, Ha Phuong Trieu, Thi Cuc Nguyen, Thi Phuong Do, Hoang Ngan Ha Le, Le Nam Khanh Tran, Hoang Ha Chu, Trung Nam Nguyen, Van Cuong Pham, Thi Kieu Oanh Nguyen, Thi Thao Do
The Schmiedeberg Medal of the German Society for Experimental and Clinical Pharmacology and Toxicology: a biographical and bibliometric analysis of the 47 recipients from 1956 to 2024
- Open Access
- Research
Jessica Marie Steinert, Roland Seifert
Celastrol protects against cisplatin-induced ovarian toxicity via modulation of PPAR-γ and AMPK
- Research
Nabil A. Alhakamy, Abdulmohsin J. Alamoudi, Wesam H. Abdulaal, Hani Choudhry, Hani Z. Asfour, Mohammed Wanees Al-Rabia, Osama M. Ashour, Ashraf B. Abdel-Naim, Amal Hofni, Esam M. Aboubakr
Biographical analysis of 32 pharmacologists persecuted under the Nazi regime: scientific careers between persecution, emigration, and new beginnings
- Open Access
- Research
Mirja Mispagel, Roland Seifert
Cantharidin attenuates the anti-β-adrenergic or anti-histaminergic or anti-serotoninergic effect of A1-adenosine receptor stimulation in the isolated human atrium
- Open Access
- Research
Rebecca Schwarz, Britt Hofmann, Uwe Kirchhefer, Joachim Neumann, Ulrich Gergs
Synthesis, characterization, and drug delivery application of carboxymethyl chitosan-CTAB self-assembling
- Research
Lijun Dong, Ge Hong, Xin Zhao, Mengmeng Jiang, Jianrong Wei, Yanyan Li
Therapeutic efficacy of baicalein and 6-(methylsulfinyl)hexyl isothiocyanate, alone or in combination with 5-fluorouracil, in the treatment of colorectal cancer
- Research
Janset S. Anzour, Mona A. Khamis, Marwan Emara
Obtusifolin mitigates acute lung injury and improves cardio-pulmonary functions in acute lung injury model by modulating oxidative stress and NF-κB signaling
- Research
Taslim B. Shaikh, Anjali Veeram, Ronak Bhupendra Patil, Madhusudana Kuncha, Rekha Shenoy, Sai Balaji Andugulapati
Imperatorin as an activator of Nrf2/ARE in mercury-induced brain damage based on rat model study, molecular docking, and molecular simulation approaches
- Research
Reshma Murali, Abilash Valsala Gopalakrishnan
Palm oil nanoemulsion enhances tocotrienol stability, antioxidant, and selective anti-melanoma activity
- Research
Ahmad Fariduddin Aththar, Farhana Raushani, Fransiska Christydira Sekaringtyas, Sjaikhurrizal El Muttaqien, Damai Ria Setyawati, Riyona Desvy Pratiwi, Muhaimin Rifa’i, Siti Irma Rahmawati, Masteria Yunovilsa Putra, Peni Ahmadi, Dwi Wahyu Indriani, Janet Tan Sui Ling, Endrika Widyastuti, Asep Bayu, A’liyatur Rosyidah
A randomized trial on efficacy of purified cannabidiol on spasticity in multiple sclerosis patients with gait problems: first report in Iran
- Research
Pegah Mousavi, Maryam Emadzadeh, Bahar Karimikhoshnoudian, Mohammad Ali Sahraian, Mehran Ghaffari, Vahid Shaygannejad, Maryam Payere, Ava Baghaei, Aram Zabeti, Mohammadali Nahayati
Inhibition of thioredoxin reductase 1 by evernic and vulpinic acids: a promising anticancer strategy on A549 cells
- Open Access
- Research
Şükran Günaydın, Şeyda Nur Kalın, Emine Karaca Sulukoğlu, Ahmet Altay, Harun Budak
Interventional effects of Tsantan Sumtang in ischemic heart disease: an integrated network pharmacology and metabolomics approach
- Research
Panpan Wang, Dejun Zhang, Yongjing Yang, Dehua Gao, Yi Zhou
Hemorrhoid risk among people with diabetes mellitus using glucose lowering agents
- Research
Wei-Syun Hu, Cheng-Li Lin
Nephroprotective activity of Eysenhardtia polystachya through antioxidant, H2S, and NO pathways
- Open Access
- Research
Emiliano de Jesús Parra-Espejel, Samara Jennifer Hipólito-Jiménez, Melissa Daniela Galicia González, Diana Montes Rojas, Viridiana Gisela Llera-Rojas, Josué A. Velázquez-Moyado
Mechanistic insights into Schisandrin C as the active anti-renal fibrosis ingredient of Schisandra chinensis: a network pharmacology analysis and transcriptomics integrated experimental verification
- Research
Xinping Yang, Xijier Qiaolongbatu, Rui Shen, Yuting Wang, Wenjing Li, Li Wang, Chunyan Zhou, Taishan Wei, Zhenghua Wu
Chicago Sky Blue 6B modulates MAPK/NF-kB pathway in rat knee osteoarthritis
- Open Access
- Research
Yejin Zhang, Weiqing Li, Yu Bai, Hehuan Lai, Jiawei Fang, Lin Ye, Dengwei He, Zhenzhong Chen
Gender- and discipline-specific bibliometric analysis of elite biomedical scientists: how is pharmacology performing?
- Open Access
- Research
Louisa Christin Fox, Roland Seifert
Piceatannol protects against cisplatin-induced ovarian toxicity in rats via modulation of PTEN/PI3 K/AKT axis
- Research
Abeer K. Alorabi, Lenah S. Binmahfouz, Amina M. Bagher, Rasheed A. Shaik, Ashraf B. Abdel-Naim, Basma G. Eid
Triazole-functionalized compounds as promising antifungal agents: Synthesis, biological evaluation, and mechanistic insights
- Research
Basmah Almohaywi, Hany E. A. Ahmed, Ahmed Kotb, Abdullah Ashraf, Moaz Alsedawy, EL-Sayed E. Habib, Ahmed K. B. Aljohani, Khalid A. Alosaimi, Aryam S. Alharbi, Samar F. Miski, Mohamed M. Elsebaei
Alpha-asarone relieves nasal inflammation, epithelial barrier damage, and mitochondrial damage in allergic rhinitis by inhibiting mitochondrial ROS via the SIRT1/PGC-1α pathway
- Open Access
- Research
Bin Xu, Weimin Gao, Haitong Li, Xiaojuan Cao, Xiaohong Chen, Nannan Dong, Lingfang Wu, Yunzhen Luo
Targeting inflammation-driven tumor progression with Zafirlukast via modulation of Jagged-1/Notch-1/Hes-1, Wnt-4/β-catenin, and VEGF signaling pathways in mice
- Research
Asmaa Saleh, Dina F. Mansour, Nahed A. Raslan, Omneya Galal, Samar Ibrahim, Mohamed M. Hafez, Lubna Jamil, Shaza M. Elhusseiny, Heba Mohammed Refat M. Selim, Ahmed Mohamed Farghly, Hammad Yahia Abdoh, Lamiaa A. Salama, Shaimaa M. Hafez, Nihal A. Mahmoud, Ahmed M. El-Dessouki
Investigating the therapeutic role of anlotinib in radiation-induced lung injury
- Research
Mouqi Bai, Gege Liang, Ruijie Sun, Yuyu Dong, Cuicui Geng, Bin Wang, Baogang Liu, Lizhe Sun
Regression of hepatic fibrosis in gamma-irradiated rats by mycophenolate mofetil: potential role of Egr-1
- Open Access
- Research
Shereen Mohamed Galal, Dalia Mohamed Mostafa, Shereen Mohamed El kiki
Galangin-loaded chitosan nanoparticles inhibit the cell cycle progression and cell proliferation by modulating cyclin-dependent kinases in breast cancer cells
- Research
Azhagu Pavithra Selvababu, Agilan Balupillai, Madhan Kumar Pichandi, Dharanidharan Dhanabalan, Babujanarthanam Ranganathan, Kalandar Ameer
Emerging trends in anticoagulation therapy: a bibliometric analysis of DOACs and endogenous coagulation pathway inhibitors
- Research
Zhe Zhu, Rong Huang, Hongli He, Rong Zhao, Xirui Li, Fangyan He, Dan Luo
Carvedilol-loaded self-nanoemulsifying drug delivery system target diabetic nephropathy: preclinical evidence of antioxidant and antifibrotic effects
- Open Access
- Research
Hanan Elimam, Zeinab Hassan, Nora A. A. Alhamshry, Khalid M. El-Say, Ahmed M. A. Akabawy
GZR101, a Novel Premixed Insulin for the Treatment of Diabetes Mellitus
- Research
Wei Chen, Cheng Cui, Wancai Xing, Yining Zhang, Anshun He, Yue Wang, Yan Huang, Nannan Zhai, Qimin Shi, Fangkai Xue, Yongchun Wang, Jun Zhang, Dongli Yu, Tian Xie, Yue Li, Zhong-Ru Gan
Therapeutic potential of tadalafil in acetic acid-induced gastric ulcer in rats: mechanisms and outcomes
- Research
Behzad Mesbahzadeh, Negar Moodi, Mohammadmehdi Hassanzadeh-Taheri, Mona Saheli, Mehran Hosseini
Bioequivalence evaluation of dexamethasone palmitate injections by intravenous injection in healthy Chinese volunteers: a 2-period crossover trial
- Research
Bingna Wang, Chen Huang, Lang Xu, Xihua Fu, Xiaojun Ma, Guoxing You, Jianfen Su
Gold nanoparticle embedded color changing film for theranostics application in wound management
- Research
Nivedita Gandhewar, Pravin Shende
LncRNA TRPM2-AS promotes cell proliferation, migration, and invasion by regulating the miR-195-5p/COP1 axis in bladder cancer
- Research
Changyuan Dai, Qingwen Li, Lili Wang, Jiajun Zhang, Shuai Yang, Xiaole Zhang
TRPV1 channel antagonist capsazepine alleviates morphine tolerance and morphine-induced neurotoxicity by preventing mitochondrial damage and apoptosis: an in vivo and in vitro study
- Open Access
- Research
Aysegul Ozturk, Ercan Ozdemir, Mustafa Ozkaraca, Ahmet Sevki Taskiran, Ahmet Altun
The effect of protocatechuic acid on nephrotoxicity induced by gentamicin in rats
- Open Access
- Research
Handan Mert, Salih Cibuk, Serkan Yildirim, Nihat Mert
Hyperoside flavonoids protect against malathion-induced mitochondrial toxicity in the differentiated SH-SY5Y cells
- Open Access
- Research
Ekramy M. Elmorsy, Huda A. Al Doghaither, Ayat B. Al-Ghafari, Manal S. Fawzy, Eman A. Toraih, Noha M. Abd El-Fadeal
Mapping breast cancer research on monoclonal antibodies: a data-driven approach using VOSviewer, Bibliometrix, and CiteSpace
- Research
Siddig Ibrahim Abdelwahab, Sivakumar S. Moni, Manal Mohamed Elhassan Taha, Khaled A. Sahli, Hatem Ahmed Salem Alqhtani, Moath Mohamed Farasani, Marwa Qadri, Abdulaziz Alarifi, Amani Khardali, Khulud Hamoud Alsaadi, Abdullah Farasani, Nizar A. Khamjan, Humaid Al-shamsi, Jobran M. Moshi, Saeed Alshahrani, Ahmed Salawi, Ahmad Assiri, Ayah Ibrahim
Synergistic amelioration of glaucoma by exogenous BDNF supplementation and microRNA-93 inhibitors via regulating Rho/ROCK and BDNF/TrkB/CREB signaling pathways
- Research
Kaiming Li, Bo Long, Wei Chen, Min Gan, Manhua Xu
The relationship of NOS3 G894 T (rs1799983) gene polymorphism in the risk of congenital heart disease: a meta-analysis and bioinformatics study
- Research
Tao Guo, Bao-Wei Meng, Gang Jin, Jia-Wei Liu, Kang Yi, Shao-E. He, Xin Zhang, Jian-Guo Xu, Yu-Xin Xu, Tao You
Nanoparticles of silver and titanium can increase temozolomide sensitivity against human glioblastoma: an in vitro study on apoptosis and inflammation
- Research
Sakshi Goswami, Yeshvandra Verma, S. V. S. Rana
Chitosan and L-histidine coated biofunctional TiO₂ composite with enhanced ROS-mediated antimicrobial and anticancer efficacy for biomedical applications
- Research
Indumathi Thangavelu, Srinivas Tadepalli, AbdulAziz A. AlGhamdi, Thalakulam Shanmugam Boopathi
Berberine mitigates colitis-associated neuroinflammation and anxiety through modulation of the AMPK/NURR1 pathway
- Research
Esraa S. Habiba, Mona Hassan Fathelbab, Marwa M. AbdElaziz, Norhan S. El-Sayed, Marwa Mahmoud Mady, Gehad M. Khamis
Historical analysis of the directors of university institutes of pharmacology in Germany and Austria in the period 1918–1963
- Open Access
- Research
Hannes Schneider, Christine Wolters, Roland Seifert
Multifunctional magnetic nanocapsules for dual delivery of siRNA and chemotherapy to MCF-7 cells (Breast cancer cells)
- Research
Sahar Mohajeri, Hashem Yaghoubi, Shima Bourang, Mehran Noruzpour
Hesperidin provides dose-dependent renal protection from cisplatin-induced injury, mediated by its regulation of Beclin-1 and LC3-II
- Research
Hoori Heidari Kahkesh, Mohammad Badavi, Mahin Dianat, Fereshteh Nejaddehbashi, Negin Amini, Khojasteh Hoseinynejad
Cytotoxic and proapoptotic effects of alizarin in mice with Ehrlich solid tumor: novel insights into ERα-mediated MDM2/p-Rb/E2F1 signaling pathway
- Open Access
- Research
Aya H. Eid, Ahmed A. Al-Karmalawy, Reda F. A. Abdelhameed, Yasser M. Mostafa, Gouda K. Helal, Eman T. Mehanna, Reem M. Hazem
Effects of resveratrol supplementation on renal function in adults: a systematic review and dose–response meta-analysis
- Research
Zahra Hajhashemy, Rahele Ziaei, Mohammad Bagherniya, Amirhossein Sahebkar
Quality by design approach for nifedipine-adsorbed fluorite-loaded calcium-low methoxy pectin beads to impart chronotherapy: in vitro and in vivo assessment
- Research
Rajesh S. Jagtap, Shrinivas K. Mohite, Sneha R. Jagtap, Sameer J. Nadaf, Sachin S. Mali, Poournima S. Sankpal, Sudarshan Singh
Effect of gallic acid in mitigating hepatorenal injuries induced by gentamicin administration in male Wistar rats
- Research
Mohammad Mehdi Behvandi, Susan Sabbagh, Reza Rostami, Ayat Moradipour, Marzieh Karami, Ashkan Jafarian, Marjan Jafarian, Leila Jafaripour, Reza Norouzirad
Evidence of lithium underuse in bipolar disorder: analysis of lithium and antipsychotic consumption, prediction of future trends, regional disparities and indicators of rational and inappropriate use in Europe
- Open Access
- Research
Lilly Josephine Bindel, Roland Seifert
Protective effects of taxifolin against gentamicin-induced nephrotoxicity in mice: modulation of oxidative stress, inflammation, apoptosis, and Nrf2 signaling
- Research
Osama Y. Althunibat, Mohammad H. Abukhalil, Alia Khwaldeh, Ahmed Abu-Zaiton, Saad Al-fawaeir
Effect of vitamin D and location of asprosin, spexin and meteorin-like antibodies in the liver of rats with isoproterenol-induced myocardial infarction
- Research
Mehmet Mustafa Erdoğan, Nevin Kocaman, Songül Yerlikaya Kavak, Tarık Salcan, Fatma Tuba Karakuzulu
Editorial Expression of Concern: Screening impacts of Tilmicosin-induced hepatic and renal toxicity in rats: protection by Rhodiola rosea extract through the involvement of oxidative stress, antioxidants, and inflammatory cytokines biomarkers
- Editorial Expression of Concern
Salwa A. Elgendy, Mohamed Mohamed Soliman, Mustafa Shukry, Lina Abdelhady Mohammed, Hend Elsayed Nasr, Saed Althobaiti, Daklallah A. Almalki, Khalid S. Alotaibi, Shatha B. Albattal, Heba A. Elnoury
Correction: Testicular weight deficits, altered variables of antioxidant defense system, spermatogenesis impairment, and inflammation induced by busulfan injection are ameliorated by gallic acid administration in rats
- Correction
Sunny O. Abarikwu, Chinedu J. Okonkwo, Ogechukwu E. Ezim, Victoria C. Obinna, Chisom E. Nebeolisa, Lauritta C. Ndufeiya-Kumasi
Correction: Historical analysis of the directors of university institutes of pharmacology in Germany and Austria in the period 1918–1963
- Open Access
- Correction
Hannes Schneider, Christine Wolters, Roland Seifert
Correction: Utility of melatonin on brain injury, synaptic transmission, and energy metabolism in rats with sepsis
- Open Access
- Correction
Gulten Ates, Sule Tamer, Elif Ozkok, Hatice Yorulmaz, Gul Ipek Gundogan, Abdullah Aksu, Nuray Balkis
Correction: The lipoxin A4 agonist BML-111 attenuates acute hepatic dysfunction induced by cecal ligation and puncture in rats
- Correction
Ghada S. El-Tanbouly, Mohammed S. El-Awady, Nermeen A. Megahed, Hassan A. El-Kashef, Hatem A. Salem
Retraction Note: The antihypertensive effect of the coadministration of exercise and eugenol in deoxycorticosterone acetate-induced hypertension in rats
- Open Access
- Retraction Note
M. A. Abdallah, Essam Omar Ibrahem, Eman A. Ali, Sara G. Tayel, Reda A. A. Abo-Elsoud
Retraction Note: Therapeutic potential of 3-acetyl coumarin against polycystic ovarian syndrome induced by letrozole using female rats
- Retraction Note
Saliha Shahbaz, Ali Sharif, Bushra Akhtar, Aisha Mobashar, Gamal A. Shazly, Amira Metouekel, Mohammed Bourhia