11.04.2023 | Original Article
Neonatal Lymphatic Flow Disorder
verfasst von:
Handan Hakyemez Toptan, Elif Ozalkaya, Nilgun Karadag, Sevilay Topcuoglu, Emre Dincer, Guner Karatekin
Erschienen in:
Indian Journal of Pediatrics
|
Ausgabe 3/2024
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Abstract
Objective
To examine and discuss patients diagnosed with acquired and congenital chylothorax in the neonatal period in the light of the literature.
Methods
The files of newborns followed-up in the neonatal intensive care unit (NICU) and diagnosed with congenital and acquired chylothorax were reviewed retrospectively. Patients with isolated chylothorax were classified as Group 1 and those with multiple lymphatic flow disorders were classified as Group 2. Antenatal and clinical features were recorded and compared between the groups.
Results
Thirteen infants were diagnosed with chylothorax; 92.3% (n = 12) of the patients were congenital. The rate of antenatal diagnosis was 61.5% (n = 8). Eight patients (61.5%) were diagnosed with hydrops fetalis. Among the cases in Group 1 and Group 2, receiving ocreotide and the incidence of sepsis (p = 0.05) were partially significant. Seven of the patients (66.6%) responded to medium chain triglycerides (MCT), and complete resolution was seen in 6 (85.7%) of the responders. Complete resolution of chylothorax fluid was observed in 7 (77.7%) of nine patients who responded to ocreotide treatment.
Conclusions
In neonatal chylothorax, the postnatal period includes a multidisciplinary approach that requires drug therapy, dietary modifications, drainage of pleural fluid, and rarely, surgery.