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Erschienen in: Zeitschrift für Rheumatologie 6/2007

01.10.2007 | Standpunkte

Nephrogene systemische Fibrose

Medizinische Detektivarbeit im 21. Jahrhundert

verfasst von: Prof. Dr. B. Manger

Erschienen in: Zeitschrift für Rheumatologie | Ausgabe 6/2007

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Zusammenfassung

Die nephrogene systemische Fibrose ist ein erstmals im Jahr 2000 beschriebenes neues Krankheitsbild bei niereninsuffizienten Patienten, das durch eine Fibrosierung von Dermis und viszeralen Organen charakterisiert ist. Vor kurzem konnte die Ätiologie dieser Erkrankung entschlüsselt werden. Der Einsatz Gadolinium-haltiger Kontrastmittel bei der Magnetresonanztomographie kann bei eingeschränkter Nierenfunktion zu einer Ablagerung des Gadoliniums im Gewebe und zur Auslösung eines Fibroseprozesses führen. Zahlreiche Publikationen der letzten Monate unterstützen diese Hypothese und haben zu aktuellen Empfehlungen der Gesundheitsbehörden für einen restriktiven Gebrauch von Gadolinium bei niereninsuffizienten Patienten geführt.
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Metadaten
Titel
Nephrogene systemische Fibrose
Medizinische Detektivarbeit im 21. Jahrhundert
verfasst von
Prof. Dr. B. Manger
Publikationsdatum
01.10.2007
Verlag
Springer-Verlag
Erschienen in
Zeitschrift für Rheumatologie / Ausgabe 6/2007
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI
https://doi.org/10.1007/s00393-007-0186-0

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