nach oben

Current Psychiatry Reports

Erschienen in:

01.11.2018 | Disaster Psychiatry: Trauma, PTSD, and Related Disorders (MJ Friedman, Section Editor)

Neurocognitive and Information Processing Biases in Posttraumatic Stress Disorder

verfasst von: Jennifer J. Vasterling, Kimberly A. Arditte Hall

Erschienen in: Current Psychiatry Reports | Ausgabe 11/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

We review recent research addressing neurocognitive and information processing abnormalities in posttraumatic stress disorder (PTSD), including studies informing direction of causality. We additionally consider neurocognition in the context of co-morbid mild traumatic brain injury (TBI) and psychosocial treatments for PTSD.

Recent Findings

Learning, memory, attention, inhibitory functions, and information processing biases frequently accompany PTSD, reflecting potential bi-directional relationships with PTSD. Although mild TBI is associated with increased risk of PTSD development and maintenance, TBI does not typically contribute significantly to sustained neurocognitive deficits in individuals with PTSD. Whereas better learning and memory is associated with mildly enhanced response to psychosocial interventions, such interventions may also improve neurocognitive performance and can be effectively provided to patients with TBI history.

Summary

PTSD is associated with cognitive abnormalities in processing both emotionally relevant and emotionally neutral information and, although mild, may underlie some PTSD symptom expression.

American Psychiatric Association. Diagnostic and statistical manual. 5th ed. Washington DC: American Psychiatric Publishing; 2013.

Pitman RK, Rasmusson AM, Koenen KC, Shin LM, Orr SP, Gilbertson MW, et al. Biological studies of post-traumatic stress disorder. Nat Rev Neurosci. 2012;13:769–87. https://doi.org/10.1038/nrn3339.CrossRefPubMedPubMedCentral

•• Scott JC, Matt GE, Wrocklage KM, Crnich C, Jordan J, Southwick SM, et al. A quantitative meta-analysis of neurocognitive functioning in posttraumatic stress disorder. Psychol Bull. 2015;141:105–40. https://doi.org/10.1037/a0038039. Meta-analysis of studies examining neurocognitive performance in adults with PTSD. CrossRefPubMed

•• Malarbi S, Abu-Rayya HM, Muscara F, Stargatt R. Neuropsychological functioning of childhood trauma and post-traumatic stress disorder: a meta-analysis. Neurosci Biobehav Rev. 2017;72:68–86. https://doi.org/10.1016/j.neurbiorev.2016.11.004. Meta-analysis of studies examining neurocognitive performance in children with PTSD. CrossRefPubMed

Barzilay R, Calkins ME, Moore TM, Wolf DH, Satterthwaite TD, Scott JC, et al. Association between traumatic stress load, psychopathology, and cognition in the Philadelphia Neurodevelopmental Cohort. Psychol Med. 2018. Advance online publication; https://doi.org/10.1017/S0033291718000880.

Nikulina V, Widom SP. Child maltreatment and executive functioning in middle adulthood: a prospective examination. Neuropsychol. 2013;27:417–27. https://doi.org/10.1037/a0032811.CrossRef

•• Brewin CR, Kleiner JS, Vasterling JJ, Field AP. Memory for emotionally neutral information in posttraumatic stress disorder. J Abnorm Psychol. 2007;116:448–63. https://doi.org/10.1037/0021-843X.116.3.448. Meta-analysis of studies examining learning and memory in adults with PTSD. CrossRefPubMed

•• Vasterling JJ, Aslan M, Lee LO, Proctor SP, Ko J, Jacob S, et al. Longitudinal associations among posttraumatic stress disorder, traumatic brain injury, and neurocognitive functioning in Army soldiers deployed to the Iraq War. J Int Neuropsychol Soc. 2018;24:311–23. https://doi.org/10.1017/S1355617717001059. Longitudinal study that measured PTSD and neurocognitive performance prior to trauma exposure, following exposure, and over 5 years later. CrossRefPubMed

Aase DM, DiGangi JA, Babione JM, Schroth C, Levy DM, Kennedy AE, et al. PTSD symptoms are associated with visual retrieval performance in OEF/OIF/OND veterans. Psychiatry Res. 2017;257:156–62. https://doi.org/10.1016/j.psychres.2017.07.041.CrossRefPubMed

10.

Wingo AP, Fani N, Bradley B, Ressler KJ. Psychological resilience and neurocognitive performance in a traumatized community sample. Depress Anxiety. 2010;27:768–74. https://doi.org/10.1002/da.20675.CrossRefPubMedPubMedCentral

11.

Holmes EA, Matthews A. Mental imagery and emotion: a special relationships? Emotion. 2005;5:453–63. https://doi.org/10.1037/1528-3542.5.4.489.CrossRef

12.

Hayes JP, VanElzakkerrr MB, Shin LM. Emotion and cognition interactions in PTSD: a review of neurocognitive and neuroimaging studies. Front Integr Neurosci. 2012;6:1–14. https://doi.org/10.3389/fnint.201200089.CrossRef

13.

Olff M, Polak R, Witteveen AB, Denys D. Executive function in posttraumatic stress disorder (PTSD) and the influence of comorbid depression. Neurobiol Learn Mem. 2014;112:114–21. https://doi.org/10.1016/j.nlm.2014.01.003.CrossRefPubMed

14.

Stricker NH, Keller JE, Castillo DT, Haaland KY. The neurocognitive performance of female veterans with posttraumatic stress disorder. J Trauma Stress. 2015;28:102–9. https://doi.org/10.1002/jts.22000.CrossRefPubMed

15.

Swick D, Honzel N, Larsen J, Ashley V, Justus T. Impaired response inhibition in veterans with post-traumatic stress disorder and mild traumatic brain injury. J Int Neuropsychol Soc. 2012;18:1–10. https://doi.org/10.1017/S13556177120000458.CrossRef

16.

Swick D, Honzel N, Larsen J, Ashley V. Increased variability as a marker of executive dysfunction in veterans with post-traumatic stress disorder. Neuropsychologia. 2013;51:3033–40. https://doi.org/10.1016/j.neuropsychologia.2013.10.008.CrossRefPubMedPubMedCentral

17.

Reinhard M, Allen N, Wong LM, Schwartz BL. Neuropsychological measurement of inhibitory control in posttraumatic stress disorder: an exploratory antisaccade paradigm. J Clin Exp Neuropsychol. 2017;39:1002–12. https://doi.org/10.1080/13803395.2017.1301389.CrossRefPubMed

18.

• DeGutis J, Esterman M, McCulloch B, Rosenblatt A, Milberg W, McGlinchey R. Posttraumatic psychological symptoms are associated with reduced inhibitory control, not general executive dysfunction. J Int Neuropsychol Soc. 2015;21:342–52. https://doi.org/10.1017/S13556177150000235. Administered a comprehensive battery of executive tasks to a OEF/OIF veterans with and without PTSD. CrossRefPubMed

19.

Aupperle RL, Melrose AJ, Stein BM, Paulus MP. Executive function and PTSD: disengaging from trauma. Neuropharmacology. 2012;62:686–94. https://doi.org/10.1016/neuropharm.2011.02.008.CrossRefPubMed

20.

Streb M, Mecklinger A, Anderson MC, Lass-Hennemann J, Michael T. Memory control ability modulates intrusive memories after analogue trauma. J Affect Disord. 2016;192:134–42. https://doi.org/10.1016/j.jad.2015.12.032.CrossRefPubMed

21.

• Clausen AN, Francisco AJ, Thelen J, Bruce J, Martin LE, McDowd J, et al. PTSD and cognitive symptoms relate to inhibition-related prefrontal activation and functional connectivity. Depress Anxiety. 2017;34:427–36. https://doi.org/10.1002/da.22613. Examined prefrontal activation and connectivity during interference processing. CrossRefPubMedPubMedCentral

22.

•• Sadeh N, Spielberg JM, Miller MW, Milberg WP, Salat DH, Amick MM, et al. Neurobiological indicators of disinhibition in posttraumatic stress disorder. Hum Brain Mapp. 2015;36:3076–86. https://doi.org/10.1002/hbm.22829. Examined alterations in both brain morphology and network connectivity in a sizable sample of OEF/OIF veterans ranging in PTSD symptom severity in relation to performance on a go/no-go task. CrossRefPubMedPubMedCentral

23.

Macklin ML, Metzger LJ, Litz BT, McNally RJ, Lasko NB, Orr SP, et al. Lower precombat intelligence is a risk factor for posttraumatic stress disorder. J Consult Clin Psychol. 1998;66:323–6. https://doi.org/10.1037/0022-006X.66.2.323.CrossRefPubMed

24.

Kremen WS, Koenen KC, Afari N, Lyons MJ. Twin studies of posttraumatic disorder: differentiating vulnerability factors from sequelae. Neuropharm. 2012;62:647–53. https://doi.org/10.1016/j.neuropharm.2011.03.012.CrossRef

25.

Parslow RA, Jorm AF. Pretrauma and posttrauma neurocognitive functioning and PTSD symptoms in a community sample of young adults. Am J Psychiatry. 2007;164:509–15. https://doi.org/10.1176/ajp.2007.164.3.509.CrossRefPubMed

26.

Marx BP, Doron-Lamarca S, Proctor SP, Vasterling JJ. The influence of pre-deployment neurocognitive functioning on post-deployment PTSD symptom outcomes among Iraq-deployed Army soldiers. J Int Neuropsychol Soc. 2009;15:840–52. https://doi.org/10.1017/S1355617709990488.CrossRefPubMed

27.

•• Bomyea J, Johnson A, Lang AJ. Information processing in PTSD: evidence for biased attentional, interpretation, and memory processes. Psychopathol Rev. 2017;4:218–43. https://doi.org/10.5127/pr.037214. A comprehensive review of methods used to assess cognitive biases in PTSD and related results. CrossRef

28.

Constans J, Kimbrell TA, Nanney JT, Marx BP, Jegley S, et al. Over-reporting bias and the modified Stroop effect in OEF/OIF veterans with and without PTSD. J Abnorm Psychol. 2014;123:81–90. https://doi.org/10.1037/a0035100.CrossRefPubMed

29.

Khanna MM, Badura-Brack AS, McDermott TJ, Embury CM, Wiesman AI, et al. Veterans with post-traumatic stress disorder exhibit altered emotional processing and attentional control during an emotional Stroop task. Psychol Med. 2017;47:2017–27. https://doi.org/10.1017/S0033291717000460.CrossRefPubMedPubMedCentral

30.

Zinchenko A, Al-Amin MM, Alam MM, Mahmud W, Kabir N, et al. Content specificity of attentional bias to threat in post-traumatic stress disorder. J Anxiety Disord. 2017;50:33–9. https://doi.org/10.1016/j.janxdis.2017.05.006.CrossRefPubMed

31.

Gindt M, Nachon O, Chanquoy L, Faure S, Garcia R. Attentional bias in post-traumatic stress symptoms or anxiety. Eur J Trauma Dissociation. 2017;1:159–64. https://doi.org/10.1016/j.ejtd.2017.05.002.CrossRef

32.

•• Naim R, Abend R, Wald I, Eldar S, Levi O, et al. Threat-related attention bias variability and posttraumatic stress. Am J Psychiatry. 2015;172:1242–50. https://doi.org/10.1176/appi.ajp.2015.14121579. Comprehensive empirical investigation of threat-related attention bias variability utilizing seven independent datasets. CrossRefPubMedPubMedCentral

33.

Thomas CL, Goegan LD, Newman KR, Arndt JE, Sears CR. Attention to threat images in individuals with clinical and subthreshold symptoms of post-traumatic stress disorder. J Anxiety Disord. 2013;27:447–55. https://doi.org/10.1016/j.janxdis.2013.05.005.CrossRefPubMed

34.

Wald I, Degnan K, Gorodetsky E, Charney DS, Fox NA, et al. Attention to threats and combat-related posttraumatic stress symptoms. JAMA Psychiatry. 2013;70:401–9. https://doi.org/10.1001/2013.CrossRefPubMedPubMedCentral

35.

Armstrong T, Bilsky SA, Zhao M, Olatunji BO. Dwelling on potential threat cues: an eye movement marker for combat-related PTSD. Depress Anxiety. 2013;30:497–502. https://doi.org/10.1002/da.22115.CrossRefPubMed

36.

Olatunji BO, Armstrong T, McHugo M, Zald DH. Heightened attentional capture by threat in veterans with PTSD. J Abnorm Psychol. 2013;122:397–405. https://doi.org/10.1037/a0030440.CrossRefPubMed

37.

• Schönenberg M, Abdelrahman T. In the face of danger: Exploring the attentional blink to emotional facial expressions in PTSD. Psychiatry Res. 2013;209:180–5. https://doi.org/10.1016/j.psychres.2012.11.011. The first study to examine differences in naturally occurring trauma and non-trauma memories in individuals with vs. without PTSD using daily diary methodology. CrossRefPubMed

38.

Hauschildt M, Wittekind C, Moritz S, Kellner M, Jelinek L. Attentional bias for affective visual stimuli in posttraumatic stress disorder and the role of depression. Psychiatry Res. 2013;207:73–9. https://doi.org/10.1016/j.psychres.2012.11.024.CrossRefPubMed

39.

Sipos ML, Bar-Haim Y, Abend R, Adler AB, Bliese PD. Postdeployment threat-related attention bias interacts with combat exposure to account for PTSD and anxiety symptoms in soldiers. Depress Anxiety. 2014;31:124–9. https://doi.org/10.1002/da.22157.CrossRefPubMed

40.

• Schäfer J, Bernstein A, Zvielli A, Höfler M, Wittchen H, et al. Attentional bias temporal dynamics predict posttraumatic stress symptoms: A prospective-longitudinal study among soldiers. Depress Anxiety. 2016;33:630–9. https://doi.org/10.1002/da.22526. Investigation in which attention bias variability was assessed longitudinally (i.e., before and after deployment to Afghanistan) in a sample of German soldiers. CrossRefPubMed

41.

Yuval K, Zvielli A, Bernstein A. Attentional bias dynamics and posttraumatic stress in survivors of violent conflict and atrocities: new directions in clinical psychological science of refugee mental health. Clin Psychol Sci. 2017;5:64–73. https://doi.org/10.1177/2167702616649349.CrossRef

42.

• Swick D, Ashley V. Enhanced attentional bias variability in post-traumatic stress disorder and its relationship to more general impairments in cognitive control. Sci Rep. 2017;7:1–10. https://doi.org/10.1038/s41598-017-15226-7. Found that attentional bias variability in PTSD was strongly correlated with variability in response time and longer response times related to cognitive failures, suggesting a more general deficit in cognitive control. CrossRef

43.

Bardeen JR, Tull MT, Daniel TA, Evenden J, Stevens EN. A preliminary investigation of the time course of attention bias variability in posttraumatic stress disorder: the moderating role of attentional control. Behav Change. 2016;33:94–111. https://doi.org/10.1017/bec.2016.5.CrossRef

44.

Iacoviello BM, Wu G, Abend R, Murrough JW, Feder A, Fruchter E, et al. Attention bias variability and symptoms of posttraumatic stress disorder. J Trauma Stress. 2014;27:232–9. https://doi.org/10.1002/jts.21899.CrossRefPubMedPubMedCentral

45.

Lin M, Hofmann SG, Qian M, Li S. Enhanced association between perceptual stimuli and trauma-related information in individuals with posttraumatic stress symptoms. J Behav Ther Exp Psychiatry. 2015;46:202–7. https://doi.org/10.1016/j.jbtep.2014.10.008.CrossRefPubMed

46.

Baumann M, Zwissler B, Schlinski I, Ruf-Leuschner M, Schauer M, et al. Directed forgetting in post-traumatic-stress-disorder: a study of refugee immigrants in Germany. Front Behav Neurosci. 2013;7:1–8. https://doi.org/10.3389/fnbeh.2013.00094.CrossRef

47.

Brewin CR. Episodic memory, perceptual memory, and their interaction: foundations for a theory of posttraumatic stress disorder. Psychol Bull. 2014;140:69–97. https://doi.org/10.1037/a0033722.CrossRefPubMed

48.

Krans J, Peeters M, Näring G, Brown AD, de Bree J, van Minnen A. Examining temporal alterations in social anxiety disorder and posttraumatic stress disorder: the relation between autobiographical memory, future goals, and current self-views. J Anxiety Disord. 2017;52:34–42. https://doi.org/10.1016/j.janxdis.2017.09.007.CrossRefPubMed

49.

Brown AD, Root JC, Romano TA, Chang LJ, Bryant RA, Hirst W. Overgeneralized autobiographical memory and future thinking in combat veterans with posttraumatic stress disorder. J Behav Ther Exp Psychiatry. 2013;44:129–34. https://doi.org/10.1016/j.jbtep.2011.11.004.CrossRefPubMed

50.

Brown AD, Addis DR, Romano TA, Marmar CR, Bryant RA, Hirst W, et al. Episodic and semantic components of autobiographical memories and imagined future events in post-traumatic stress disorder. Memory. 2014;22:595–604. https://doi.org/10.1080/09658211.2013.807842.CrossRefPubMed

51.

Bryant RA, Sutherland K, Guthrie RM. Impaired specific autobiographical memory as a risk factor for posttraumatic stress after trauma. J Abnorm Psychol. 2007;116:837–41. https://doi.org/10.1037/0021-843X.116.4.837.CrossRefPubMed

52.

• Schönfeld S, Ehlers A. Posttraumatic stress disorder and autobiographical memories in everyday life. Clin Psychol Sci. 2017;5:325–40. https://doi.org/10.1177/2167702616688878. The first study to examine differences in naturally occurring trauma and non-trauma memories in individuals with vs. without PTSD using daily diary methodology. CrossRefPubMedPubMedCentral

53.

Ehlers A, Clark DM. A cognitive model of posttraumatic stress disorder. Behav Res Ther. 2000;38:319–45. https://doi.org/10.1016/S0005-7967(99)00123-0.CrossRefPubMed

54.

Amir N, Coles ME, Foa EB. Automatic and strategic activation and inhibition of threat-relevant information in posttraumatic stress disorder. Cognit Ther Res. 2002;26:645–55. https://doi.org/10.1023/A:1020309326976.CrossRef

55.

Kimble M, Batterink L, Marks E, Ross C, Fleming K. Negative expectancies in posttraumatic stress disorder: neurophysiological (N400) and behavioral evidence. J Psychiatry Res. 2012;46:849–55. https://doi.org/10.1016/j.jpsychires.2012.03.023.CrossRef

56.

• Boffa JW, Norr AM, Tock JL, Amir N, Schmidt NB. Development of the interpretation bias index for PTSD. Cognit Ther and Res. 2018: Advance online publication. https://doi.org/10.1007/s10608-018-9915-8. Describes development and validation of a brief, self-report measure of PTSD-related interpretation biases. CrossRefPubMedPubMedCentral

57.

•• Woud ML, Verwoerd J, Krans J. Modification of cognitive biases related to posttraumatic stress: a systematic review and research agenda. Clin Psychol Rev. 2017;54:81–95. https://doi.org/10.1016/j.cpr.2017.04.003. Comprehensive review of research on cognitive bias modification for PTSD-related biases conducted to date. CrossRefPubMed

58.

Zatzick DF, Rivara FP, Jurkovich GJ, Hoge CW, Wang J, Fan MY, et al. Multisite investigation of traumatic brain injuries, posttraumatic stress disorder, and self-reported health and cognitive impairments. Arch Gen Psychiatry. 2010;12:1291–300. https://doi.org/10.1001/archgenpsychiatry.2010.158.CrossRef

59.

•• O’Donnell ML, Alkemade N, Creamer MC, McFarlane AC, Silove D, Bryant RA, et al. The long-term psychiatric sequelae of severe injury: a 6-year follow-up study. J Clin Psychiatry. 2016;77:e473–9. https://doi.org/10.4088/JCP.14m09721. Longitudinal study of mild TBI as a risk factor for PTSD in a civilian trauma sample incorporating both short- and long-term outcomes. CrossRefPubMed

60.

•• Stein MB, Kessler RC, Heeringa SG, Jain S, Campbell-Sills L, Colpe LJ, et al. Longitudinal evaluation of the effect of deployment acquired traumatic brain injury on posttraumatic stress and related disorders: results from the Army Study to Assess Risk and Resilience (Army STARRS). Am J Psychiatry. 2015;172:1101–11. https://doi.org/10.1176/appi.ajp.2015.14121572. Large prospective study of deployment-related mild TBI as a risk factor for PTSD using a population-based US Army sample. CrossRefPubMedPubMedCentral

61.

Yurgil KA, Barkauskas DA, Vasterling JJ, Nievergelt CM, Larson GE, Schork NJ, et al. Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines. JAMA Psychiatry. 2014;71:149–57. https://doi.org/10.1001/jamapsychiatry.2013.3080.CrossRefPubMed

62.

Cnossen MC, Scholten AC, Lingsma HF, Synnot A, Haagsma J, Steyerberg EW, et al. Predictors of major depression ad posttraumatic stress disorder following traumatic brain injury: a systematic review and meta-analysis. J Neuropsychiatry Clin Neurosci. 2017;29:206–24. https://doi.org/10.1176/appi.neuropsych.16090165.CrossRefPubMed

63.

Guo X, Edmed SL, Anderson V, Kenardy J. Neurocognitive predictors of posttraumatic stress disorder in children 6 months after traumatic brain injury: a prospective study. Neuropsychol. 2017;31:84–92. https://doi.org/10.1037/neu0000305.CrossRef

64.

Karr JE, Areshenkoff CN, Garcia-Barrera MA. The neuropsychological outcomes of concussion: a systematic review of the meta-analyses on the cognitive sequelae of mild traumatic brain injury. Neuropsychol. 2014;28:321–36. https://doi.org/10.1037/neu0000037.CrossRef

65.

Spira JL, Lathan CE, Bleiberg J, Tsao JW. The impact of multiple concussions on emotional distress, post-concussive symptoms, and neurocognitive functioning in active duty United States marines independent of combat exposure or emotion distress. J Neurotrauma. 2014;31:1823–34. https://doi.org/10.1089/neu.2014.3363.CrossRefPubMedPubMedCentral

66.

King PR, Donnelly KT, Wade M, Donnelly JP, Dunnam M, Warner G, et al. The relationships between premilitary vocational aptitude assessment, traumatic brain injury, and postdeployment cognitive functions in combat veterans. Arch Clin Neuropsychol. 2014;29:391–402. https://doi.org/10.1039/arclin/acu011.CrossRefPubMed

67.

Martindale SL, Morissette SB, Rowland JA, Dolan SL. Sleep quality affects cognitive functioning in returning combat veterans beyond combat exposure, PTSD, and mild TBI history. Neuropsychol. 2017;31:93–104. https://doi.org/10.1037/rep0000312.CrossRef

68.

Massey JS, Meares S, Batchelor J, Bryant RA. An exploratory study of the association of acute posttraumatic stress, depression, and pain to cognitive functioning in mild traumatic brain injury. Neuropsychol. 2015;29:530–42. https://doi.org/10.1037/neu0000192.CrossRef

69.

Storzbach D, O’Neil ME, Roost SM, Kowalski H, Iverson GL, Binder LM, et al. Comparing the neuropsychological test performance of Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) veterans with and without blast exposure, mild traumatic brain injury, and posttraumatic stress symptoms. J Int Neuropsychol Soc. 2015;21:353–63. https://doi.org/10.1017/S13556177150000326.CrossRefPubMed

70.

• Verfaellie M, Lee LO, Lafleche G, Spiro A. Sleep disturbance mediates the relationship between PTSD and cognitive outcomes in blast-exposed OEF/OIF veterans. J Head Trauma Rehabil. 2016;31:309–19. https://doi.org/10.1097/HTR.0000000000000197. Examines sleep as a mediator of PTSD and cognitive performance in blast-exposed military veterans.. CrossRefPubMedPubMedCentral

71.

Hayes JP, Miller DR, Lafleche G, Salat DH, Verfaellie M. The nature of white matter abnormalities in blast-related mild traumatic brain injury. Neuroimage Clin. 2015;8:148–56. https://doi.org/10.1016/j.nicl.2015.04.001.CrossRefPubMedPubMedCentral

72.

Clark AL, Sorg SF, Scheihser DM, Luc N, Bondi MW, Sanderson M, et al. Deep white matter hyperintensities affect verbal memory independent of PTSD symptoms in veterans with mild traumatic brain injury. Brain Inj. 2016;30:864–71. https://doi.org/10.3109/02699052.2016.1144894.CrossRefPubMed

73.

Porter KE, Stein MB, Martis B, Avallone KM, McSweeney LB, Smith ER, et al. Postconcussive symptoms (PCS) following combat-related traumatic brain injury (TBI) in veterans with posttraumatic stress disorder (PTSD): influence of TBI, PTSD, and depression on symptoms measured by the Neurobehavioral Symptom Inventory (NSI). J Psychiatr Res. 2018;102:8–13. https://doi.org/10.1016/jjpsychires.2018.03.004.CrossRefPubMed

74.

Scott JC, Harb G, Brownlow JA, Greene J, Gur RC, Ross RJ. Verbal memory functioning moderates psychotherapy treatment response for PTSD-related nightmares. Behav Res Ther. 2017;91:24–32. https://doi.org/10.1016/j.brat.2017.01.004.CrossRefPubMed

75.

Sripada RK, Rauch SA, Tuerk PW, Smith E, Defever AM, Mayer RA, et al. Mild traumatic brain injury and treatment response in prolonged exposure for PTSD. J Trauma Stress. 2013;26:369–75. https://doi.org/10.1002/jts.21813.CrossRefPubMed

76.

Wolf GK, Kretzmer T, Crawford E, Thors C, Wagner HR, Strom TQ, et al. Prolonged exposure therapy with veterans and active duty personnel diagnosed with PTSD and traumatic brain injury. J Trauma Stress. 2015;28:339–47. https://doi.org/10.1097/NMD.0000000000000594.CrossRefPubMed

77.

•• Wolf GK, Mauntel GJ, Kretzmer T, Crawford E, Thors C, Strom TQ, et al. Comorbid posttraumatic stress disorder and traumatic brain injury: generalization of prolonged exposure PTSD outcomes to postconcussive symptoms in veterans and active duty service members. J Head Trauma Rehabil. 2018;33:E53–63. https://doi.org/10.1097/HTR.0000000000000344. Treatment study showing both the effectiveness of prolonged exposure therapy for PTSD in reducing both PTSD symptoms and postconcussive symptoms in military veterans and service members with PTSD and co-morbid TBI. CrossRefPubMed

78.

Gros DF, Lancaster CL, Horner MD, Szafranski DD, Back SE. The influence of traumatic brain injury on treatment outcomes of Concurrent Treatment for PTSD and Substance Use Disorders Using Prolonged Exposure (COPE) in veterans. Compr Psychiatry. 2017;78:48–53. https://doi.org/10.1016/j.comppsych.2017.07.004.CrossRefPubMedPubMedCentral

79.

Nijdam MJ, de Vries G, Gersons BPR, Olff M. Response to psychotherapy for posttraumatic stress disorder: the role of pretreatment verbal memory. J Clin Psychiatry. 2015;76:e1023–8. https://doi.org/10.4088/JCP.14m09438.CrossRefPubMed

80.

• Haaland KY, Sadek JR, Keller JF, Castillo DT. Neurocognitive correlates of successful treatment of PTSD in female veterans. J Int Neuropsychol Soc. 2016;22:643–51. https://doi.org/10.1017/S13556177160000424. Examined both prediction of PTSD treatment response from neuropsychological measures and change in neuropsychological performance following treatment and in relation to symptom improvement. CrossRefPubMed

81.

Akbarian F, Bajoghli H, Haghighi M, Kalak N, Holsboer-Trachsler E, Brand S. The effectiveness of cognitive behavioral therapy with respect to psychological symptoms and recovering autobiographical memory in patients suffering from post-traumatic stress disorder. Neuropsychiatr Dis Treat. 2015;11:395–404. https://doi.org/10.2147/NDT.S79581.CrossRefPubMedPubMedCentral

82.

Nijdam MJ, Martens IJ, Reitsma JB, Gersons BPR, Olff M. Neurocognitive functioning over the course of trauma-focused psychotherapy for PTSD: changes in verbal memory and executive functioning. Br J Clin Psychol. 2018; https://doi.org/10.1111/bjc.12183.CrossRefPubMed

83.

Roy MJ, Costanzo ME, Blair JR, Rizzo AA. Compelling evidence that exposure therapy for PTSD normalizes brain function. Stud Health Technol Inform. 2014;199:61–5. https://doi.org/10.3233/978-1-61499-401-5-61.CrossRefPubMed

84.

Levy-Gigi E, Szabo C, Kelemen O, Keri S. Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy. Biol Psychiatry. 2013;74:793–800. https://doi.org/10.1016/j.biopsych.2013.05.017.CrossRefPubMed

85.

• Shou H, Yang Z, Sattherwaite TD, Cook PA, Bruce SE, Shinohara RT, et al. Cognitive behavioral therapy increases amygdala connectivity within the cognitive control network in both MDD and PTSD. Neuroimage Clin. 2017;14:464–70. https://doi.org/10.1016/j.nicl.2017.01.030. Neuroimaging study that measured neural connectivity within the cognitive control network before and after cognitive processing therapy. CrossRefPubMedPubMedCentral

86.

Seligowski AV, Lee DJ, Bardeen JR, Orcutt HK. Emotion regulation and posttraumatic stress symptoms: a meta-analysis. Cognit Behav Ther. 2015;44:87–102. https://doi.org/10.1080/16506073.2014.980753.CrossRef

87.

Szabo YZ, Warnecke AJ, Newton TL, Valentine JC. Rumination and posttraumatic stress symptoms in trauma-exposed adults: a systematic review and meta-analysis. Anxiety Stress Coping. 2017;30:394–414. https://doi.org/10.1080/10615806.2017.1313835.CrossRef

88.

Yang Y, Cao S, Shields GS, Teng Z, Liu Y. The relationship between rumination and core executive functions: a meta-analysis. Depress Anxiety. 2017;34:37–50. https://doi.org/10.1002/da.22539.CrossRefPubMed

89.

Sumner JA. The mechanisms underlying overgeneral autobiographical memory: an evaluative review of evidence for the CaR-FA-X model. Clin Psychol Rev. 2012;32:34–48. https://doi.org/10.1016/j.cpr.2011.10.003.CrossRefPubMed

90.

Gabrys RL, Dixon K, Holahan MR, Anisman H. Self-reported mild traumatic brain injuries in relation to rumination and depressive symptoms: moderating role of sex differences and a brain-derived neurotrophic factor gene polymorphism. Clin J Sport Med. 2017: Advance online publication. https://doi.org/10.1097/JSM.0000000000000550.

91.

Schacter DL, Addis DR, Buckner RL. Episodic simulation of future events: concepts data and applications. Ann N Y Acad Sci. 2008;1124:39–60. https://doi.org/10.1196/annals.1440.001.CrossRefPubMed

92.

Kleim B, Graham B, Fihosy S, Stott R, Ehlers A. Reduced specificity in episodic future thinking in posttraumatic stress disorder. Clin Psychol Sci. 2014;2:165–73. https://doi.org/10.1177/2167702613495199.CrossRefPubMedPubMedCentral

93.

Burri A, Maercker A, Krammer S, Simmen-Janevska K. Childhood trauma and PTSD symptoms increase the risk of cognitive impairment in a sample of former indentured child laborers in old age. PLoS One. 2013;8:e57826. https://doi.org/10.1371/journal.pone.0057826.CrossRefPubMedPubMedCentral

94.

Peavy GM, Jacobson MW, Salmon DP, Gamst AC, Patterson TL, Goldman S, et al. The influence of chronic stress on dementia-related diagnostic change in older adults. Alzheimer Dis Assoc Disord. 2012;26:260–6. https://doi.org/10.1097/WAD.0b013e3182389a9c.CrossRefPubMedPubMedCentral

95.

Yaffe K, Vittinghoff E, Lindquist K, Barnes D, Covinsky KE, Neylan T, et al. Post-traumatic stress disorder and risk of dementia among U.S. veterans. Arch Gen Psychiatry. 2010;67:608–13. https://doi.org/10.1001/archgenpsychiatry.2010.61.CrossRefPubMedPubMedCentral

96.

• Weiner MW, Harvey D, Hayes J, Landau SM, Aisen PS, Petersen RC, et al. Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer’s disease in Vietnam veterans using the Alzheimer’s Disease Neuroimaging Initiative: preliminary report. Alzheimers Dement. 2017;3:177–88. https://doi.org/10.1016/j.trci.2017.02.005. Examined neuropathological indices of Alzheimer’s disease in relation to PTSD and TBI in a sample of Vietnam veterans. CrossRef

97.

Kubzansky LD, Koenen KC, Spiro A, Vokonas P, Sparrow D. Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the normative aging study. Arch Gen Psychiatry. 2007;64:109–16. https://doi.org/10.1001/archpsyc.64.1.109.CrossRefPubMed

98.

Wolf EJ, Maniates H, Nugent N, Maihofer AX, Armstrong D, Ratanatharathorn A, et al. Traumatic stress and accelerated DNA methylation age: a meta-analysis. Psychoneuroendocrinology. 2018;92:123–34. https://doi.org/10.1016/j.psyneuen.2017.12.007.CrossRefPubMed

99.

• Wolf EJ, Logue MW, Hayes JP, Sadeh N, Schichman SA, Stone A, et al. Accelerated DNA methylation age: associations with PTSD and neural integrity. Psychoneuroendocrinology. 2016;63:155–62. https://doi.org/10.1016/j.psyneuen.2015.09.020. Examination of epigenetic changes associated with PTSD and neural integrity, including cognitive functioning. CrossRefPubMed

Titel: Neurocognitive and Information Processing Biases in Posttraumatic Stress Disorder
verfasst von: Jennifer J. Vasterling
Kimberly A. Arditte Hall
Publikationsdatum: 01.11.2018
Verlag: Springer US
Erschienen in: Current Psychiatry Reports / Ausgabe 11/2018
Print ISSN: 1523-3812
Elektronische ISSN: 1535-1645
DOI: https://doi.org/10.1007/s11920-018-0964-1

Neu im Fachgebiet Psychiatrie

23.04.2024 | Demenz | Nachrichten

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Neurocognitive and Information Processing Biases in Posttraumatic Stress Disorder

Abstract

Purpose of Review

Recent Findings

Summary

Neu im Fachgebiet Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Psychiatrie

Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2018

Posttraumatic Stress Disorder and Death From Suicide

Sex Differences in Vulnerability to Prenatal Stress: a Review of the Recent Literature

PTSD in Children Below the Age of 6 Years

Autism Spectrum Disorder and Transition-Aged Youth

Suicide Risk and the Menstrual Cycle: a Review of Candidate RDoC Mechanisms

Building Child and Adolescent Psychiatry Expertise in Ghana Through Training and Knowledge Dissemination: a Review of the Initial Collaboration Stages, Opportunities, and Challenges

Neu im Fachgebiet Psychiatrie

Demenzkranke durch Antipsychotika vielfach gefährdet

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Psychiatrie