Erschienen in:
24.10.2017 | Original Article
Neurodevelopmental outcome in survivors of hypoxic ischemic encephalopathy without cerebral palsy
verfasst von:
Breda C. Hayes, Elaine Doherty, Andrea Grehan, Cathy Madigan, Cliona McGarvey, Siobhan Mulvany, Tom G. Matthews, Mary D. King
Erschienen in:
European Journal of Pediatrics
|
Ausgabe 1/2018
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Abstract
To access outcome following hypoxic ischemic encephalopathy (HIE), survivors without cerebral palsy were invited for formal developmental assessment. Children aged ≥ 42 months were assessed using the NEPSY-2, Movement Assessment Battery for Children 2 (Movement ABC-2), Behavior Rating Inventory of Executive Function, and the Child Behavior Checklist. Children aged < 42 months were assessed using the Bayley Scales of Infant and Toddler Development, Third Edition (BSITD-3). One hundred forty-six children attended for assessments [Grade 1 (112), Grade 2 (33), and Grade 3 (1)]. BSITD-3 did not identify significant rates of impairment on cognitive, motor, or language subtests. A significant proportion of children scored < 3rd percentile on the adaptive behavior scale. In older age groups, difficulties were seen in 16/24 NEPSY-2 subtests and on timed assessments using Movement ABC-2. Difficulties arose especially in the “control” aspects of cognition and behavior. Behavioral difficulties were common with internalizing problems predominating. There was a graded effect with grade 2 cases differing significantly from grade 1 cases.
Conclusion: Following HIE, children may experience attention, memory, and behavior difficulties which are not always evident at a young age. The adaptive behavior questionnaire may be a useful tool to select children requiring developmental surveillance beyond 2 years of age.
What is known:
• Diversity of outcome across grades of HIE is reported and few studies have looked at the milder consequences of HIE at school age. |
What is new:
• Following HIE children may experience attention, memory, and behavior difficulties which are not always evident at a young age.
• The adaptive behavior questionnaire may be a useful tool to select children requiring developmental surveillance beyond 2 years of age. |