Neurological Research and Practice

Key design elements of successful acute ischemic stroke treatment trials

• Open Access
• Review

L. Yperzeele, A. Shoamanesh, Y. V. Venugopalan, S. Chapman, M. V. Mazya, M. Charalambous, V. Caso, W. Hacke, P. M. Bath, I. Koltsov

The “SALPARE study” of spontaneous intracerebral haemorrhage—part 2-early CT predictors of outcome in ICH: keeping it simple

• Open Access
• Research Article

Renzo Manara, Ludovica De Rosa, Francesca Vodret, Caterina Kulyk, Renato Pennella, Eleonora Contrino, Giacomo Cester, Francesco Causin, Alessio Pieroni, Federica Viaro, Maria Luisa Zedde, Rosario Pascarella, Rosa Napoletano, Claudio Baracchini

Echocardiography in acute stroke patients: a nationwide analysis in departments with certified stroke units in Germany

• Open Access
• Research Article

Timolaos Rizos, Ekkehart Jenetzky, Darius Günther Nabavi, Karl Georg Haeusler, Rolf Wachter, Martin Ossenbrink, Peter Arthur Ringleb, Otto Busse

Ulnar nerve thickness at the elbow on longitudinal ultrasound view in control subjects

• Open Access
• Research article

José Manuel Pardal-Fernández, Inmaculada Diaz-Maroto, Tomás Segura, Carlos de Cabo

The “SALPARE study” of spontaneous intracerebral hemorrhage: part 1

• Open Access
• Research article

Ludovica De Rosa, Renzo Manara, Francesca Vodret, Caterina Kulyk, Florian Montano, Alessio Pieroni, Federica Viaro, Maria Luisa Zedde, Rosa Napoletano, Mario Ermani, Claudio Baracchini

The impact of regional deprivation on stroke incidence, treatment, and mortality in Germany

• Open Access
• Research article

Matthias Hans Belau, Heiko Becher, Maya Riefflin, Dirk Bartig, Lars Schwettmann, Christopher Jan Schwarzbach, Armin Grau

Relationship between post-stroke dysphagia and pharyngeal sensory impairment

• Open Access
• Research article

Bendix Labeit, Anne Jung, Sigrid Ahring, Stephan Oelenberg, Paul Muhle, Malte Roderigo, Fiona Wenninger, Jonas von Itter, Inga Claus, Tobias Warnecke, Rainer Dziewas, Sonja Suntrup-Krueger

Survival, prognostic factors, hospitalization time and clinical performance status after first cerebral relapse or progression in 54 patients with primary CNS lymphoma not eligible for high dose chemotherapy: a retrospective analysis

• Open Access
• Research article

Sabine Seidel, Thomas Kowalski, Verena Nilius-Eliliwi, Roland Schroers, Uwe Schlegel

Telestroke networks for area-wide access to endovascular stroke treatment

• Open Access
• Review

Hans Worthmann, S. Winzer, R. Schuppner, C. Gumbinger, J. Barlinn

Stroke thrombolysis or not for an intraventricular thrombus

• Open Access
• Letter to the editor

Josef Finsterer, Sounira Mehri

Author response to “Stroke thrombolysis or not for an intraventricular thrombus”

• Open Access
• Comment

Dimitrios Tsiptsios

Blood pressure management in ischemic stroke patients undergoing mechanical thrombectomy

• Open Access
• Review

Michael De Georgia, Theodore Bowen, K. Rose Duncan, Alex Bou Chebl

Infective endocarditis and stroke: when does it bleed? A single center retrospective study

• Open Access
• Research article

L. Nitsch, O. Shirvani Samani, M. Silaschi, M. Schafigh, S. Zimmer, G. C. Petzold, C. Kindler, F. J. Bode

Beyond treatment of chronic pain: a scoping review about epidural electrical spinal cord stimulation to restore sensorimotor and autonomic function after spinal cord injury

• Open Access
• Review

Antonia Luz, Rüdiger Rupp, Rezvan Ahmadi, Norbert Weidner

Guideline “Transient Global Amnesia (TGA)” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): S1-guideline

• Open Access
• Guidelines

Dirk Sander, Thorsten Bartsch, Florian Connolly, Christian Enzinger, Urs Fischer, Nils Nellessen, Holger Poppert, Kristina Szabo, Helge Topka

Correction to Competing Interests

• Open Access
• Correction

Clinical surrogates of dysautonomia predict lethal outcome in COVID-19 on intensive care unit

• Open Access
• Research article

Marcel Seungsu Woo, Christina Mayer, Marlene Fischer, Stefan Kluge, Kevin Roedl, Christian Gerloff, Patrick Czorlich, Götz Thomalla, Julian Schulze zur Wiesch, Nils Schweingruber

EXERTION: a pilot trial on the effect of aerobic, smartwatch-controlled exercise on stroke recovery: effects on motor function, structural repair, cognition, mental well-being, and the immune system

• Open Access
• Clinical trial protocol

Frederike A. Straeten, Stephanie van Zyl, Bastian Maus, Jochen Bauer, Heiner Raum, Catharina C. Gross, Sabine Bruchmann, Nils C. Landmeyer, Cornelius Faber, Jens Minnerup, Antje Schmidt-Pogoda

Access to and application of recanalizing therapies for severe acute ischemic stroke caused by large vessel occlusion

• Open Access
• Standard operating procedure

Julian Bösel, Gordian J. Hubert, Jessica Jesser, Markus A. Möhlenbruch, Peter A. Ringleb

Video-EEG-monitoring to guide antiseizure medication withdrawal

• Open Access
• Research article

Laurien K. L. Dhaenens-Meyer, Elisabeth Schriewer, Yvonne G. Weber, Stefan Wolking

Extent of routine diagnostic cardiac work-up at certified German stroke units participating in the prospective MonDAFIS study

• Open Access
• Research article

Manuel C. Olma, Serdar Tütüncü, Ulrike Grittner, Claudia Kunze, Muhammad Jawad-Ul-Qamar, Paulus Kirchhof, Joachim Röther, Götz Thomalla, Roland Veltkamp, Ulrich Laufs, Darius G. Nabavi, Peter U. Heuschmann, Matthias Endres, Karl Georg Haeusler

Large-vessel-occlusion in patients with previous ischemic stroke: an analysis of adherence to secondary preventive medication for different etiologies

• Open Access
• Research article

Konstantin Kohlhase, Jan Hendrik Schäfer, Lisa Marie Tako, Laurent M. Willems, Elke Hattingen, Ferdinand O. Bohmann, Christian Grefkes, Felix Rosenow, Adam Strzelczyk

Design and implementation of ParkinsonAKTIV: an interventional study to evaluate the effectiveness of a novel online platform to guide quickcard-based treatment decisions

• Open Access
• Clinical trial protocol

Katharina Achtert, Tessa Huchtemann, Maria Altendorf, Linda Kerkemeyer, Malte Haring, Carina Lummer, Lena Frenz, Theresa Becking, Jonas Friedmann, Philip Mildner, Katharina Schwarze, Lars Steinhaus, Volker Amelung, Tobias Warnecke

The impact of thymectomy in subgroups of Myasthenia gravis patients: a single center longitudinal observation

• Open Access
• Research article

Hruy Menghesha, Michael Schroeter, Christopher Nelke, Tobias Ruck, Georg Schlachtenberger, Clara Welskop, Amina Camo, Matthias Heldwein, Gerardus Bennink, Thorsten Wahlers, Servet Bölükbas, Fabian Doerr, Khosro Hekmat

Guideline “Motor neuron diseases” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie)

• Open Access
• Guidelines

Susanne Petri, Torsten Grehl, Julian Grosskreutz, Martin Hecht, Andreas Hermann, Sarah Jesse, Paul Lingor, Wolfgang Löscher, André Maier, Benedikt Schoser, Marcus Weber, Albert C. Ludolph

Myofibrillar myopathy: a rare but important differential diagnosis of camptocormia in a patient with Parkinson’s Disease

• Open Access
• Letter to the editor

Jan Niklas Petry-Schmelzer, Angela Abicht, Michael T. Barbe, Gilbert Wunderlich

Normal values ​​for ultrasound parameters of the ulnar nerve require homogeneous, healthy cohorts

• Open Access
• Letter to the editor

Josef Finsterer

Multiple cerebral microinfarcts: an uncommon presentation of Cerebral Amyloid Angiopathy-related inflammation

• Open Access
• Letter to the editor

Aikaterini Theodorou, Athanasios Tsibonakis, Ioannis S Pateras, Georgia Kaloudi, Eleni Bakola, Maria Chondrogianni, Elissavet Andreadou, Ioannis G Panayiotides, Georgios Tsivgoulis

Current practice and attitudes of stroke physicians towards rhythm-control therapy for stroke prevention: results of an international survey

• Open Access
• Research article

Märit Jensen, Rustam Al-Shahi Salman, G. Andre Ng, H. Bart van der Worp, Peter Loh, Bruce C. V. Campbell, Jonathan M. Kalman, Michael D. Hill, Luciano A. Sposato, Jason G. Andrade, Andreas Metzner, Paulus Kirchhof, Götz Thomalla

Alzheimer’s disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C

• Open Access
• Research article

Franz Felix Konen, Hannah Benedictine Maier, Alexandra Neyazi, Stefan Bleich, Konstantin Neumann, Thomas Skripuletz

Novel inflammatory biomarkers associated with stroke severity: results from a cross-sectional stroke cohort study

• Open Access
• Research article

Lino Braadt, Markus Naumann, Dennis Freuer, Timo Schmitz, Jakob Linseisen, Michael Ertl

Derivation and validation of a screening tool for stroke-associated sepsis

• Open Access
• Research article

Sebastian Stösser, Lisa Kleusch, Alina Schenk, Matthias Schmid, Gabor C. Petzold

Subthalamic 85 Hz deep brain stimulation improves walking pace and stride length in Parkinson’s disease patients

• Open Access
• Research article

F. Mügge, U. Kleinholdermann, A. Heun, M. Ollenschläger, J. Hannink, D. J. Pedrosa

Clinical characteristics and outcomes of patients with recurrent status epilepticus episodes

• Open Access
• Research article

Kristina Bauer, Felix Rosenow, Susanne Knake, Laurent M. Willems, Leena Kämppi, Adam Strzelczyk

SOP: acute hyperkinetic movement disorders

• Open Access
• Standard operating procedure

Anna Sauerbier, Alexandra Gronostay, Haidar S. Dafsari

Hematoma expansion in intracerebral hemorrhage – the right target?

• Open Access
• Review

David Haupenthal, Stefan Schwab, Joji B. Kuramatsu

Differential effects of gender and age on dynamic subjective visual vertical

• Open Access
• Letter to the editor

Johannes Gerb, Lena Padovan, Nicole Lehrer, Thomas Brandt, Marianne Dieterich

A familial missense ACTA2 variant p.Arg198Cys leading to Moyamoya-like arteriopathy with straight course of the intracranial arteries, aortic aneurysm and lethal aortic dissection

• Open Access
• Research article

Jan K. Focke, Markus Kraemer

Introducing electronic monitoring of disease activity in patients with chronic inflammatory demyelinating polyneuropathy (EMDA CIDP): trial protocol of a proof of concept study

• Open Access
• Clinical trial protocol

Lars Masanneck, Jan Voth, Niklas Huntemann, Menekse Öztürk, Christina B. Schroeter, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki

Clinical characteristics of patients with suspected Alzheimer’s disease within a CSF Aß-ratio grey zone

• Open Access
• Research article

Dariia Yosypyshyn, Domantė Kučikienė, Inez Ramakers, Jörg B. Schulz, Kathrin Reetz, Ana Sofia Costa

Determinants of quality of life in adults with epilepsy: a multicenter, cross-sectional study from Germany

• Open Access
• Research article

Kai Siebenbrodt, Laurent M. Willems, Felix von Podewils, Peter Michael Mross, Michael Strüber, Lisa Langenbruch, Laura Bierhansl, Iris Gorny, Juliane Schulz, Bernadette Gaida, Nadine Conradi, Annika Süß, Felix Rosenow, Adam Strzelczyk

Effects of body mass index on the immune response within the first days after major stroke in humans

• Open Access
• Research article

Johanna Ruhnau, Christin Heuer, Carl Witt, Sonya Ceesay, Juliane Schulze, Stefan Gross, Maria Waize, Marie-Luise Kromrey, Jens-Peter Kühn, Sönke Langner, Uwe Grunwald, Barbara M. Bröker, Astrid Petersmann, Antje Steveling, Alexander Dressel, Antje Vogelgesang

Milestones in the history of neurocritical care

• Open Access
• Review

Rainer Kollmar, Michael De Georgia

German guidelines on community-acquired acute bacterial meningitis in adults

• Open Access
• Guidelines

Matthias Klein, Carsten Abdel-Hadi, Robert Bühler, Beatrice Grabein, Jennifer Linn, Roland Nau, Bernd Salzberger, Dirk Schlüter, Konrad Schwager, Hayrettin Tumani, Jörg Weber, Hans-Walter Pfister

Camptocormia due to myotinilopathy, Parkinson’s disease, or both?

• Open Access
• Letter to the editor

Josef Finsterer

Resting state EEG as biomarker of cognitive training and physical activity’s joint effect in Parkinson’s patients with mild cognitive impairment

• Open Access
• Research article

Carlos Trenado, Paula Trauberg, Saskia Elben, Karina Dimenshteyn, Ann-Kristin Folkerts, Karsten Witt, Daniel Weiss, Inga Liepelt-Scarfone, Elke Kalbe, Lars Wojtecki

Video-EEG monitoring as a valuable tool for antiseizure medication withdrawal in patients with epilepsy: implications for clinical practice and public health policies

• Open Access
• Letter to the editor

Obed Okwoli Apochi

Can ChatGPT explain it? Use of artificial intelligence in multiple sclerosis communication

• Open Access
• Letter to the editor

Hernan Inojosa, Stephen Gilbert, Jakob Nikolas Kather, Undine Proschmann, Katja Akgün, Tjalf Ziemssen

No evidence for neuronal damage or astrocytic activation in cerebrospinal fluid of Neuro-COVID-19 patients with long-term persistent headache

• Open Access
• Letter to the editor

Laura de Boni, Alexandru Odainic, Natalie Gancarczyk, Luisa Kaluza, Christian P. Strassburg, Xenia A. K. Kersting, Ullrich Wüllner, Susanne V. Schmidt, Gabor C. Petzold

Facial nerve neurographies in intensive care unit-acquired weakness

• Open Access
• Research article

Maximilian Lochter, Martin Sommer, Onnen Moerer, Caspar Stephani

Independent external validation of a stroke recurrence score in patients with embolic stroke of undetermined source

• Open Access
• Research article

Thies Ingwersen, Manuel C. Olma, Eckhard Schlemm, Carola Mayer, Bastian Cheng, Serdar Tütüncü, Paulus Kirchhof, Roland Veltkamp, Joachim Röther, Ulrich Laufs, Darius G. Nabavi, George Ntaios, Matthias Endres, Karl Georg Haeusler, Götz Thomalla

Evolution of neurodegeneration in patients with normal pressure hydrocephalus: a monocentric follow up study

• Open Access
• Research article

Leonard L. Klemke, Katharina Müller-Schmitz, Aschwin Kolman, Rüdiger J. Seitz

Frequency and satisfaction of conventional and complementary or alternative therapies for neuromuscular disorders

• Open Access
• Research article

Lene Änne Böhne, Corinna Wirner, Benedikt Schoser, Carsten Schröter, Petra Baum

Reply to: Camptocormia due to myotinilopathy, Parkinson’s disease, or both?

• Open Access
• Comment

Jan Niklas Petry-Schmelzer, Gilbert Wunderlich

INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas

• Open Access
• Clinical trial protocol

Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas, Dietmar Krex, Peter Vajkoczy, Antje Wick, Inga Harting, Felix Sahm, Andreas von Deimling, Martin Bendszus, Wolfgang Wick, Michael Platten

The role of creatine kinase in distinguishing generalized tonic–clonic seizures from psychogenic non-epileptic seizures (PNES) and syncope: a retrospective study and meta-analysis of 1300 patients

• Open Access
• Review

Ramy Abdelnaby, Anas Elgenidy, Jan Heckelmann, Mahmoud Mostafa Bedewy, Ahmed Samy Shabib, Mohamed Ayman Ebrahim, Khaled Abdelmoneim Elmenawi, Imene Maallem, Merna Wagih Youssef, Abdelrahman M. Attia, Mostafa Hossam Moawad, Khaled Ashraf Mohamed, Ahmed Gaballa

Outcome analysis for patients with subarachnoid hemorrhage and vasospasm including endovascular treatment

• Open Access
• Research article

Sina Burth, Jan Meis, Dorothea Kronsteiner, Helena Heckhausen, Klaus Zweckberger, Meinhard Kieser, Wolfgang Wick, Christian Ulfert, Markus Möhlenbruch, Peter Ringleb, Silvia Schönenberger

Maternal immunoglobulin treatment can reduce severity of fetal acetylcholine receptor antibody-associated disorders (FARAD)

• Open Access
• Letter to the editor

Matthias Wassenberg, Andreas Hahn, Anna Mück, Heidrun H. Krämer

Validation of a German-language modified Rankin Scale structured telephone interview at 3 months in a real-life stroke cohort

• Open Access
• Research article

Lennart Steffen Milles, Doreen Pommeranz, Woon Hyung Chae, Jordi Kühne Escolà, Christoph Kleinschnitz, Martin Köhrmann, Benedikt Frank

Rendezvous intervention using combined surgical carotid endarterectomy followed by endovascular thrombectomy in patients with acute tandem occlusions: a proof-of-concept experience at a tertiary care center

• Open Access
• Research article

Norma J. Diel, Stefan T. Gerner, Omar Alhaj Omar, Johannes Kalder, Enikö Manz, Paula R. Keschenau, Tobias Struffert, Thomas Brueckner, Hagen B. Huttner, Thorsten R. Doeppner

Symptomatic treatment options for Huntington’s disease (guidelines of the German Neurological Society)

• Open Access
• Guidelines

Carsten Saft, Jean-Marc Burgunder, Matthias Dose, Hans Heinrich Jung, Regina Katzenschlager, Josef Priller, Huu Phuc Nguyen, Kathrin Reetz, Ralf Reilmann, Klaus Seppi, Georg Bernhard Landwehrmeyer

Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke

• Open Access
• Research article

Marie Schäbitz, Leona Möller, Anja Friedrich, Nele Klein, Alkisti Kitsiou, Isabell Greeve, Anja Gerstner, Leonard Wulff, Wolf-Rüdiger Schäbitz, Lars Timmermann, Andreas Rogalewski

Differential diagnosis of chorea (guidelines of the German Neurological Society)

• Open Access
• Guidelines

Carsten Saft, Jean-Marc Burgunder, Matthias Dose, Hans Heinrich Jung, Regina Katzenschlager, Josef Priller, Huu Phuc Nguyen, Kathrin Reetz, Ralf Reilmann, Klaus Seppi, Georg Bernhard Landwehrmeyer

Correction: Guideline “Transient Global Amnesia (TGA)” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): S1-guideline

• Open Access
• Correction

Dirk Sander, Thorsten Bartsch, Florian Connolly, Christian Enzinger, Urs Fischer, Nils Nellessen, Holger Poppert, Kristina Szabo, Helge Topka

The impact of referring patients with drug-resistant focal epilepsy to an epilepsy center for presurgical diagnosis

• Open Access
• Research article

Leonhard Mann, Felix Rosenow, Adam Strzelczyk, Elke Hattingen, Laurent M. Willems, Patrick N. Harter, Katharina Weber, Catrin Mann

Temporary and highly variable recovery of neuromuscular dysfunction by electrical stimulation in the follow-up of acute critical illness neuromyopathy: a pilot study

• Open Access
• Research article

Madona Sekhniashvili, Petra Baum, Klaus V. Toyka

Outcome of endovascular stroke therapy in a large mandatory stroke-registry

• Open Access
• Research article

Sonja Hyrenbach, Susanne Rode, Martin Schabet, Michael Daffertshofer, Karin Schoser, Stephan Neumaier, Peter A. Ringleb