Skip to main content
Erschienen in: DNP - Der Neurologe & Psychiater 6/2016

06.06.2016 | Zertifizierte Fortbildung

Neuropsychologische Leistungsfähigkeit

Kognitive Reserve und Potenzial im Alter

verfasst von: Julius Steding, Prof. Dr. med. habil. Vjera Holthoff-Detto

Erschienen in: DNP – Die Neurologie & Psychiatrie | Ausgabe 6/2016

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die kognitive Reserve ist die aktive Fähigkeit des Gehirns Prozesse zu initiieren, die trotz physiologischer oder pathologischer Hirnveränderungen die kognitive Leistungsfähigkeit kompensieren. Sie wird durch unterschiedliche Einflussfaktoren wie Bildung, Beruf, Beziehungen und Bewegung über die Lebensspanne geprägt und spielt für das gesunde kognitive Altern eine zentrale Rolle:
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Riley KP, Snowdon DA, Markesbery WR. Alzheimer’s neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study. Annals of neurology. 2002;51(5):567–77.CrossRefPubMed Riley KP, Snowdon DA, Markesbery WR. Alzheimer’s neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study. Annals of neurology. 2002;51(5):567–77.CrossRefPubMed
2.
Zurück zum Zitat SantaCruz KS, Sonnen JA, Pezhouh MK, Desrosiers MF, Nelson PT, Tyas SL. Alzheimer disease pathology in subjects without dementia in 2 studies of aging: the Nun Study and the Adult Changes in Thought Study. Journal of Neuropathology & Experimental Neurology. 2011;70(10):832–40.CrossRef SantaCruz KS, Sonnen JA, Pezhouh MK, Desrosiers MF, Nelson PT, Tyas SL. Alzheimer disease pathology in subjects without dementia in 2 studies of aging: the Nun Study and the Adult Changes in Thought Study. Journal of Neuropathology & Experimental Neurology. 2011;70(10):832–40.CrossRef
3.
Zurück zum Zitat Villeneuve S, Belleville S. Cognitive reserve and neuronal changes associated with aging. Psychologie & neuropsychiatrie du vieillissement. 2010;8(2):133. Villeneuve S, Belleville S. Cognitive reserve and neuronal changes associated with aging. Psychologie & neuropsychiatrie du vieillissement. 2010;8(2):133.
4.
Zurück zum Zitat Negash S, Wilson RS, Leurgans SE, Wolk DA, Schneider JA, Buchman AS, et al. Resilient brain aging: characterization of discordance between Alzheimer’s disease pathology and cognition. Current Alzheimer research. 2013;10(8):844.CrossRefPubMedPubMedCentral Negash S, Wilson RS, Leurgans SE, Wolk DA, Schneider JA, Buchman AS, et al. Resilient brain aging: characterization of discordance between Alzheimer’s disease pathology and cognition. Current Alzheimer research. 2013;10(8):844.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Valenzuela MJ, Sachdev P. Brain reserve and cognitive decline: a non-parametric systematic review. Psychological medicine. 2006 Aug;36(8):1065–73.CrossRefPubMed Valenzuela MJ, Sachdev P. Brain reserve and cognitive decline: a non-parametric systematic review. Psychological medicine. 2006 Aug;36(8):1065–73.CrossRefPubMed
6.
Zurück zum Zitat Valenzuela MJ, Sachdev P. Brain reserve and dementia: a systematic review. Psychological medicine. 2006 Apr;36(4):441–54.CrossRefPubMed Valenzuela MJ, Sachdev P. Brain reserve and dementia: a systematic review. Psychological medicine. 2006 Apr;36(4):441–54.CrossRefPubMed
7.
Zurück zum Zitat Opdebeeck C, Martyr A, Clare L. Cognitive reserve and cognitive function in healthy older people: a meta-analysis. Aging, Neuropsychology, and Cognition. 2016;23(1):40–60.CrossRef Opdebeeck C, Martyr A, Clare L. Cognitive reserve and cognitive function in healthy older people: a meta-analysis. Aging, Neuropsychology, and Cognition. 2016;23(1):40–60.CrossRef
8.
Zurück zum Zitat Hindle JV, Martyr A, Clare L. Cognitive reserve in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders. 2014;20(1):1–7.CrossRef Hindle JV, Martyr A, Clare L. Cognitive reserve in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders. 2014;20(1):1–7.CrossRef
9.
Zurück zum Zitat Foley JM, Ettenhofer ML, Kim MS, Behdin N, Castellon SA, Hinkin CH. Cognitive reserve as a protective factor in older HIV-positive patients at risk for cognitive decline. Applied Neuropsychology: Adult. 2012;19(1):16–25.CrossRef Foley JM, Ettenhofer ML, Kim MS, Behdin N, Castellon SA, Hinkin CH. Cognitive reserve as a protective factor in older HIV-positive patients at risk for cognitive decline. Applied Neuropsychology: Adult. 2012;19(1):16–25.CrossRef
10.
Zurück zum Zitat Benedict RH, Morrow SA, Guttman BW, Cookfair D, Schretlen DJ. Cognitive reserve moderates decline in information processing speed in multiple sclerosis patients. Journal of the International Neuropsychological Society. 2010;16(05):829–35.CrossRefPubMed Benedict RH, Morrow SA, Guttman BW, Cookfair D, Schretlen DJ. Cognitive reserve moderates decline in information processing speed in multiple sclerosis patients. Journal of the International Neuropsychological Society. 2010;16(05):829–35.CrossRefPubMed
11.
Zurück zum Zitat Pascual-Leone A, Amedi A, Fregni F, Merabet LB. The plastic human brain cortex. Annu Rev Neurosci. 2005;28:377–401.CrossRefPubMed Pascual-Leone A, Amedi A, Fregni F, Merabet LB. The plastic human brain cortex. Annu Rev Neurosci. 2005;28:377–401.CrossRefPubMed
13.
Zurück zum Zitat Ward DD, Summers MJ, Saunders NL, Vickers JC. Modeling cognitive reserve in healthy middle-aged and older adults: the Tasmanian Healthy Brain Project. International Psychogeriatrics. 2015;27(04):579–89.CrossRefPubMed Ward DD, Summers MJ, Saunders NL, Vickers JC. Modeling cognitive reserve in healthy middle-aged and older adults: the Tasmanian Healthy Brain Project. International Psychogeriatrics. 2015;27(04):579–89.CrossRefPubMed
14.
Zurück zum Zitat Zahodne LB, Manly JJ, Brickman AM, Narkhede A, Griffith EY, Guzman VA, et al. Is residual memory variance a valid method for quantifying cognitive reserve? A longitudinal application. Neuropsychologia. 2015;77:260–6.CrossRefPubMed Zahodne LB, Manly JJ, Brickman AM, Narkhede A, Griffith EY, Guzman VA, et al. Is residual memory variance a valid method for quantifying cognitive reserve? A longitudinal application. Neuropsychologia. 2015;77:260–6.CrossRefPubMed
15.
Zurück zum Zitat Pettigrew C, Soldan A, Li S, Lu Y, Wang M-C, Selnes OA, et al. Relationship of cognitive reserve and APOE status to the emergence of clinical symptoms in preclinical Alzheimer’s disease. Cognitive neuroscience. 2013;4(3-4):136–42.CrossRefPubMed Pettigrew C, Soldan A, Li S, Lu Y, Wang M-C, Selnes OA, et al. Relationship of cognitive reserve and APOE status to the emergence of clinical symptoms in preclinical Alzheimer’s disease. Cognitive neuroscience. 2013;4(3-4):136–42.CrossRefPubMed
16.
Zurück zum Zitat Corder E, Saunders A, Strittmatter W, Schmechel D, Gaskell P, Small G, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families. Science. 1993;261(5123):921–3.CrossRefPubMed Corder E, Saunders A, Strittmatter W, Schmechel D, Gaskell P, Small G, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families. Science. 1993;261(5123):921–3.CrossRefPubMed
17.
Zurück zum Zitat Rhinn H, Fujita R, Qiang L, Cheng R, Lee JH, Abeliovich A. Integrative genomics identifies APOE ε4 effectors in Alzheimer’s disease. Nature. 2013;500(7460):45–50.CrossRefPubMed Rhinn H, Fujita R, Qiang L, Cheng R, Lee JH, Abeliovich A. Integrative genomics identifies APOE ε4 effectors in Alzheimer’s disease. Nature. 2013;500(7460):45–50.CrossRefPubMed
18.
Zurück zum Zitat Blennow K, de Leon MJ, Zetterberg H. Alzheimer’s disease. The Lancet. 2006;368(9533):387–403.CrossRef Blennow K, de Leon MJ, Zetterberg H. Alzheimer’s disease. The Lancet. 2006;368(9533):387–403.CrossRef
19.
Zurück zum Zitat Ihle A, Bunce D, Kliegel M. APOE ε4 and cognitive function in early life: a meta-analysis. Neuropsychology. 2012;26(3):267.CrossRefPubMed Ihle A, Bunce D, Kliegel M. APOE ε4 and cognitive function in early life: a meta-analysis. Neuropsychology. 2012;26(3):267.CrossRefPubMed
20.
Zurück zum Zitat Cook CJ, Fletcher JM. Can education rescue genetic liability for cognitive decline? Social Science & Medicine. 2015;127:159–70.CrossRef Cook CJ, Fletcher JM. Can education rescue genetic liability for cognitive decline? Social Science & Medicine. 2015;127:159–70.CrossRef
21.
Zurück zum Zitat Shadlen M-F, Larson EB, Wang L, Phelan EA, McCormick WC, Jolley L, et al. Education modifies the effect of apolipoprotein epsilon 4 on cognitive decline. Neurobiology of Aging. 2005;26(1):17–24.CrossRefPubMed Shadlen M-F, Larson EB, Wang L, Phelan EA, McCormick WC, Jolley L, et al. Education modifies the effect of apolipoprotein epsilon 4 on cognitive decline. Neurobiology of Aging. 2005;26(1):17–24.CrossRefPubMed
22.
Zurück zum Zitat Bialystok E, Craik FI, Freedman M. Bilingualism as a protection against the onset of symptoms of dementia. Neuropsychologia. 2007;45(2):459–64.CrossRefPubMed Bialystok E, Craik FI, Freedman M. Bilingualism as a protection against the onset of symptoms of dementia. Neuropsychologia. 2007;45(2):459–64.CrossRefPubMed
23.
Zurück zum Zitat Craik FI, Bialystok E, Freedman M. Delaying the onset of Alzheimer disease Bilingualism as a form of cognitive reserve. Neurology. 2010;75(19):1726–9.CrossRefPubMedPubMedCentral Craik FI, Bialystok E, Freedman M. Delaying the onset of Alzheimer disease Bilingualism as a form of cognitive reserve. Neurology. 2010;75(19):1726–9.CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Siedlecki KL, Stern Y, Reuben A, Sacco RL, Elkind MS, Wright CB. Construct validity of cognitive reserve in a multiethnic cohort: The Northern Manhattan Study. Journal of the International Neuropsychological Society. 2009;15(04):558–69.CrossRefPubMedPubMedCentral Siedlecki KL, Stern Y, Reuben A, Sacco RL, Elkind MS, Wright CB. Construct validity of cognitive reserve in a multiethnic cohort: The Northern Manhattan Study. Journal of the International Neuropsychological Society. 2009;15(04):558–69.CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Stern Y, Zarahn E, Habeck C, Holtzer R, Rakitin BC, Kumar A, et al. A common neural network for cognitive reserve in verbal and object working memory in young but not old. Cereb Cortex. 2008;18(4):959–67.CrossRefPubMed Stern Y, Zarahn E, Habeck C, Holtzer R, Rakitin BC, Kumar A, et al. A common neural network for cognitive reserve in verbal and object working memory in young but not old. Cereb Cortex. 2008;18(4):959–67.CrossRefPubMed
27.
Zurück zum Zitat Gold BT. Lifelong bilingualism and neural reserve against Alzheimer’s disease: A review of findings and potential mechanisms. Behavioural Brain Research. 2015;281:9–15.CrossRefPubMed Gold BT. Lifelong bilingualism and neural reserve against Alzheimer’s disease: A review of findings and potential mechanisms. Behavioural Brain Research. 2015;281:9–15.CrossRefPubMed
28.
Zurück zum Zitat Puente AN, Lindbergh CA, Miller LS. The Relationship Between Cognitive Reserve and Functional Ability is Mediated by Executive Functioning in Older Adults. The Clinical Neuropsychologist. 2015;29(1):67–81.CrossRefPubMed Puente AN, Lindbergh CA, Miller LS. The Relationship Between Cognitive Reserve and Functional Ability is Mediated by Executive Functioning in Older Adults. The Clinical Neuropsychologist. 2015;29(1):67–81.CrossRefPubMed
29.
Zurück zum Zitat Bartres-Faz D, Sole-Padulles C, Junque C, Rami L, Bosch B, Bargallo N, et al. Interactions of cognitive reserve with regional brain anatomy and brain function during a working memory task in healthy elders. Biological psychology. 2009;80(2):256–9.CrossRefPubMed Bartres-Faz D, Sole-Padulles C, Junque C, Rami L, Bosch B, Bargallo N, et al. Interactions of cognitive reserve with regional brain anatomy and brain function during a working memory task in healthy elders. Biological psychology. 2009;80(2):256–9.CrossRefPubMed
30.
Zurück zum Zitat Bartres-Faz D, Arenaza-Urquijo EM. Structural and functional imaging correlates of cognitive and brain reserve hypotheses in healthy and pathological aging. Brain topography. 2011;24(3-4):340–57.CrossRefPubMed Bartres-Faz D, Arenaza-Urquijo EM. Structural and functional imaging correlates of cognitive and brain reserve hypotheses in healthy and pathological aging. Brain topography. 2011;24(3-4):340–57.CrossRefPubMed
31.
Zurück zum Zitat Yoo SW, Han CE, Shin JS, Seo SW, Na DL, Kaiser M, et al. A network flow-based analysis of cognitive reserve in normal ageing and Alzheimer’s disease. Scientific Reports. 2015;5. Yoo SW, Han CE, Shin JS, Seo SW, Na DL, Kaiser M, et al. A network flow-based analysis of cognitive reserve in normal ageing and Alzheimer’s disease. Scientific Reports. 2015;5.
32.
Zurück zum Zitat Bozzali M, Dowling C, Serra L, Spano B, Torso M, Marra C, et al. The impact of cognitive reserve on brain functional connectivity in Alzheimer’s disease. Journal of Alzheimer’s Disease. 2015;44(1):243–50.PubMed Bozzali M, Dowling C, Serra L, Spano B, Torso M, Marra C, et al. The impact of cognitive reserve on brain functional connectivity in Alzheimer’s disease. Journal of Alzheimer’s Disease. 2015;44(1):243–50.PubMed
33.
Zurück zum Zitat Harrison SL, Sajjad A, Bramer WM, Ikram MA, Tiemeier H, Stephan BCM. Exploring strategies to operationalize cognitive reserve: A systematic review of reviews. Journal of Clinical and Experimental Neuropsychology. 2015;37(3):253–64.CrossRefPubMed Harrison SL, Sajjad A, Bramer WM, Ikram MA, Tiemeier H, Stephan BCM. Exploring strategies to operationalize cognitive reserve: A systematic review of reviews. Journal of Clinical and Experimental Neuropsychology. 2015;37(3):253–64.CrossRefPubMed
34.
Zurück zum Zitat Stern Y. Cognitive reserve and Alzheimer disease. Alzheimer Disease & Associated Disorders. 2006;20(2):112–7.CrossRef Stern Y. Cognitive reserve and Alzheimer disease. Alzheimer Disease & Associated Disorders. 2006;20(2):112–7.CrossRef
35.
Zurück zum Zitat Fratiglioni L, Wang HX. Brain reserve hypothesis in dementia. Journal of Alzheimer’s disease: JAD. 2007;12(1):11–22.PubMed Fratiglioni L, Wang HX. Brain reserve hypothesis in dementia. Journal of Alzheimer’s disease: JAD. 2007;12(1):11–22.PubMed
36.
Zurück zum Zitat Larson EB, Wang L, Bowen JD, McCormick WC, Teri L, Crane P, et al. Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals of Internal Medicine. 2006;144(2):73–81.CrossRefPubMed Larson EB, Wang L, Bowen JD, McCormick WC, Teri L, Crane P, et al. Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Annals of Internal Medicine. 2006;144(2):73–81.CrossRefPubMed
37.
Zurück zum Zitat Jedrziewski MK, Ewbank DC, Wang H, Trojanowski JQ. The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function: Results From the National Long-Term Care Survey. American Journal of Alzheimer’s Disease & Other Dementias. 2014;29(4):372–8CrossRef Jedrziewski MK, Ewbank DC, Wang H, Trojanowski JQ. The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function: Results From the National Long-Term Care Survey. American Journal of Alzheimer’s Disease & Other Dementias. 2014;29(4):372–8CrossRef
38.
Zurück zum Zitat Helmer C, Damon D, Letenneur L, Fabrigoule C, Barberger-Gateau P, Lafont S, et al. Marital status and risk of Alzheimer’s disease A French population-based cohort study. Neurology. 1999;53(9):1953-.CrossRefPubMed Helmer C, Damon D, Letenneur L, Fabrigoule C, Barberger-Gateau P, Lafont S, et al. Marital status and risk of Alzheimer’s disease A French population-based cohort study. Neurology. 1999;53(9):1953-.CrossRefPubMed
39.
Zurück zum Zitat Fratiglioni L, Wang H-X, Ericsson K, Maytan M, Winblad B. Influence of social network on occurrence of dementia: a communitybased longitudinal study. The Lancet. 2000;355(9212):1315–9.CrossRef Fratiglioni L, Wang H-X, Ericsson K, Maytan M, Winblad B. Influence of social network on occurrence of dementia: a communitybased longitudinal study. The Lancet. 2000;355(9212):1315–9.CrossRef
40.
Zurück zum Zitat Alipour H, Goldust M. The association between blood pressure components and cognitive functions and cognitive reserve. Clinical and Experimental Hypertension. 2016;38(1):95–9.CrossRefPubMed Alipour H, Goldust M. The association between blood pressure components and cognitive functions and cognitive reserve. Clinical and Experimental Hypertension. 2016;38(1):95–9.CrossRefPubMed
41.
Zurück zum Zitat Shatenstein B, Barberger-Gateau P. Prevention of Age-Related Cognitive Decline: Which Strategies, When, and for Whom? Journal of Alzheimer’s Disease. 2015;48(1):35–53.CrossRefPubMed Shatenstein B, Barberger-Gateau P. Prevention of Age-Related Cognitive Decline: Which Strategies, When, and for Whom? Journal of Alzheimer’s Disease. 2015;48(1):35–53.CrossRefPubMed
42.
Zurück zum Zitat Lenehan ME, Summers MJ, Saunders NL, Summers JJ, Vickers JC. Relationship between education and age-related cognitive decline: a review of recent research. Psychogeriatrics. 2015;15(2):154–62.CrossRef Lenehan ME, Summers MJ, Saunders NL, Summers JJ, Vickers JC. Relationship between education and age-related cognitive decline: a review of recent research. Psychogeriatrics. 2015;15(2):154–62.CrossRef
43.
Zurück zum Zitat Lenehan ME, Summers MJ, Saunders NL, Summers JJ, Ward DD, Ritchie K, et al. Sending Your Grandparents to University Increases Cognitive Reserve: The Tasmanian Healthy Brain Project. 2015. Lenehan ME, Summers MJ, Saunders NL, Summers JJ, Ward DD, Ritchie K, et al. Sending Your Grandparents to University Increases Cognitive Reserve: The Tasmanian Healthy Brain Project. 2015.
44.
Zurück zum Zitat Clark DO, Xu H, Unverzagt FW, Hendrie H. Does targeted cognitive training reduce educational disparities in cognitive function among cognitively normal older adults? International Journal of Geriatric Psychiatry. 2015. Clark DO, Xu H, Unverzagt FW, Hendrie H. Does targeted cognitive training reduce educational disparities in cognitive function among cognitively normal older adults? International Journal of Geriatric Psychiatry. 2015.
45.
Zurück zum Zitat Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, et al. Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain imaging and behavior. 2015:1–9. Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, et al. Cognitive activity, cognitive function, and brain diffusion characteristics in old age. Brain imaging and behavior. 2015:1–9.
46.
Zurück zum Zitat Sander MC, Lindenberger U, Werkle-Bergner M. Lifespan age differences in working memory: A two-component framework. Neuroscience & Biobehavioral Reviews. 2012;36(9):2007–33.CrossRef Sander MC, Lindenberger U, Werkle-Bergner M. Lifespan age differences in working memory: A two-component framework. Neuroscience & Biobehavioral Reviews. 2012;36(9):2007–33.CrossRef
47.
Zurück zum Zitat Stern Y, Blumen HM, Rich LW, Richards A, Herzberg G, Gopher D. Space Fortress game training and executive control in older adults: a pilot intervention. Aging, Neuropsychology, and Cognition. 2011;18(6):653–77.CrossRef Stern Y, Blumen HM, Rich LW, Richards A, Herzberg G, Gopher D. Space Fortress game training and executive control in older adults: a pilot intervention. Aging, Neuropsychology, and Cognition. 2011;18(6):653–77.CrossRef
48.
Zurück zum Zitat Corbett A, Owen A, Hampshire A, Grahn J, Stenton R, Dajani S, et al. The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial. Journal of the American Medical Directors Association. 2015;16(11):990–7.CrossRefPubMed Corbett A, Owen A, Hampshire A, Grahn J, Stenton R, Dajani S, et al. The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial. Journal of the American Medical Directors Association. 2015;16(11):990–7.CrossRefPubMed
49.
Zurück zum Zitat Panza F, Solfrizzi V, Logroscino G. Age-related hearing impairment [mdash] a risk factor and frailty marker for dementia and AD. Nature Reviews Neurology. 2015;11(3):166–75.CrossRefPubMed Panza F, Solfrizzi V, Logroscino G. Age-related hearing impairment [mdash] a risk factor and frailty marker for dementia and AD. Nature Reviews Neurology. 2015;11(3):166–75.CrossRefPubMed
50.
Zurück zum Zitat Wayne RV, Johnsrude IS. A review of causal mechanisms underlying the link between age-related hearing loss and cognitive decline. Ageing research reviews. 2015;23:154–66.CrossRefPubMed Wayne RV, Johnsrude IS. A review of causal mechanisms underlying the link between age-related hearing loss and cognitive decline. Ageing research reviews. 2015;23:154–66.CrossRefPubMed
51.
Zurück zum Zitat Teixeira CVL, Gobbi LTB, Corazza DI, Stella F, Costa JLR, Gobbi S. Non-pharmacological interventions on cognitive functions in older people with mild cognitive impairment (MCI). Archives of Gerontology and Geriatrics. 2012;54(1):175–80.CrossRefPubMed Teixeira CVL, Gobbi LTB, Corazza DI, Stella F, Costa JLR, Gobbi S. Non-pharmacological interventions on cognitive functions in older people with mild cognitive impairment (MCI). Archives of Gerontology and Geriatrics. 2012;54(1):175–80.CrossRefPubMed
52.
Zurück zum Zitat Jeong Hong Y, Hye Jang E, Hwang J, Hoon Roh J, Lee J-H. The Efficacy of Cognitive Intervention Programs for Mild Cognitive Impairment: A Systematic Review. Current Alzheimer research. 2015;12(6):527–42.CrossRef Jeong Hong Y, Hye Jang E, Hwang J, Hoon Roh J, Lee J-H. The Efficacy of Cognitive Intervention Programs for Mild Cognitive Impairment: A Systematic Review. Current Alzheimer research. 2015;12(6):527–42.CrossRef
53.
Zurück zum Zitat Sacco G, Caillaud C, Ben Sadoun G, Robert P, David R, Brisswalter J. Exercise Plus Cognitive Performance Over and Above Exercise Alone in Subjects with Mild Cognitive Impairment. Journal of Alzheimer’s Disease. 2015;50(1):19–25.CrossRefPubMed Sacco G, Caillaud C, Ben Sadoun G, Robert P, David R, Brisswalter J. Exercise Plus Cognitive Performance Over and Above Exercise Alone in Subjects with Mild Cognitive Impairment. Journal of Alzheimer’s Disease. 2015;50(1):19–25.CrossRefPubMed
54.
Zurück zum Zitat Morimoto SS, Kanellopoulos D, Manning KJ, Alexopoulos GS. Diagnosis and treatment of depression and cognitive impairment in late life. Annals of the New York Acadademy of Sciences. 2015;1345(1):36–46.CrossRef Morimoto SS, Kanellopoulos D, Manning KJ, Alexopoulos GS. Diagnosis and treatment of depression and cognitive impairment in late life. Annals of the New York Acadademy of Sciences. 2015;1345(1):36–46.CrossRef
55.
Zurück zum Zitat Sheline YI, Barch DM, Garcia K, Gersing K, Pieper C, Welsh-Bohmer K, et al. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biological Psychiatry. 2006;60(1):58–65.CrossRefPubMed Sheline YI, Barch DM, Garcia K, Gersing K, Pieper C, Welsh-Bohmer K, et al. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biological Psychiatry. 2006;60(1):58–65.CrossRefPubMed
56.
Zurück zum Zitat Opdebeeck C, Quinn C, Nelis SM, Clare L. Does cognitive reserve moderate the association between mood and cognition? A systematic review. Reviews in Clinical Gerontology. 2015;25(03):181–93.CrossRef Opdebeeck C, Quinn C, Nelis SM, Clare L. Does cognitive reserve moderate the association between mood and cognition? A systematic review. Reviews in Clinical Gerontology. 2015;25(03):181–93.CrossRef
57.
Zurück zum Zitat Simon SS, Cordás TA, Bottino C. Cognitive Behavioral Therapies in older adults with depression and cognitive deficits: a systematic review. International Journal of Geriatric Psychiatry. 2015;30(3):223–33.CrossRefPubMed Simon SS, Cordás TA, Bottino C. Cognitive Behavioral Therapies in older adults with depression and cognitive deficits: a systematic review. International Journal of Geriatric Psychiatry. 2015;30(3):223–33.CrossRefPubMed
Metadaten
Titel
Neuropsychologische Leistungsfähigkeit
Kognitive Reserve und Potenzial im Alter
verfasst von
Julius Steding
Prof. Dr. med. habil. Vjera Holthoff-Detto
Publikationsdatum
06.06.2016
Verlag
Springer Medizin
Erschienen in
DNP – Die Neurologie & Psychiatrie / Ausgabe 6/2016
Print ISSN: 2731-8168
Elektronische ISSN: 2731-8176
DOI
https://doi.org/10.1007/s15202-016-1050-3

Weitere Artikel der Ausgabe 6/2016

DNP - Der Neurologe & Psychiater 6/2016 Zur Ausgabe

Kurz gemeldet

ZNS-Dialoge® 2016

Neu in den Fachgebieten Neurologie und Psychiatrie