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Erschienen in: Dysphagia 5/2021

07.11.2020 | Review

Neuromuscular Specializations of the Human Hypopharyngeal Muscles

verfasst von: Mohammed Elrabie Ahmed Mohammed, Liancai Mu, Hesham Mostafa Abdelfattah

Erschienen in: Dysphagia | Ausgabe 5/2021

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Abstract

The hypopharyngeal muscles in humans play a vital role in swallowing, speech, and respiration. Increasing evidence indicates that these muscles are specialized to perform life-sustaining upper aerodigestive functions. This review aims to provide current knowledge regarding the key structural, physiological, and biochemical features of the hypopharyngeal muscles, including innervation, contractile properties, histochemistry, biochemical properties, myosin heavy chain (MyHC) expression and regulation, and age-related alterations. These would clarify the unique neuromuscular specializations of the human hypopharyngeal muscles for a better understanding of the functions and pathological conditions of the pharynx and for the development of novel therapies to treat related upper airway disorders.
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Metadaten
Titel
Neuromuscular Specializations of the Human Hypopharyngeal Muscles
verfasst von
Mohammed Elrabie Ahmed Mohammed
Liancai Mu
Hesham Mostafa Abdelfattah
Publikationsdatum
07.11.2020
Verlag
Springer US
Erschienen in
Dysphagia / Ausgabe 5/2021
Print ISSN: 0179-051X
Elektronische ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-020-10212-0

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