Erschienen in:
31.05.2017 | Correspondence
NG2 plays a role in neuroinflammation but is not expressed by immune cells
verfasst von:
Maja Kitic, Khalad Karram, Nicole Israel, Nir Yogev, Sonja M. Lacher, Yilang Tang, Hatice Yigit, Jan Bauer, Florian Wanke, Anela Knezovic, Jacqueline Trotter, Florian C. Kurschus, Ari Waisman
Erschienen in:
Acta Neuropathologica
|
Ausgabe 2/2017
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Excerpt
Nerve/glial antigen 2 (NG2) is a large transmembrane chondroitin sulphate proteoglycan expressed mainly by oligodendrocyte precursor cells in the developing and adult central nervous system (CNS) and pericytes in various organs throughout the body [
14]. Numerous studies reported increased levels of this molecule after CNS injury, but its relevance remained questionable [
5,
6,
9,
11]. …