Nodular Fasciitis of the Oral Cavity with Partial Spontaneous Regression (Nodular Fasciitis)
- 01.03.2013
- Sine qua non Clinicopathologic Correlat
Erschienen in:
- Verfasst von
- Marina Lara de Carli
- Karin Sá Fernandes
- Décio dos Santos Pinto Jr.
- Andrea Lusvarghi Witzel
- Marília Trierveiler Martins
- Erschienen in
- Head and Neck Pathology | Ausgabe 1/2013
Abstract
Nodular fasciitis is a lesion found in the subcutaneous fascia that micoscopically presents as a benign proliferation of fibroblasts and myofibroblasts, which may be mistaken for a sarcoma due to clinically rapid growth. Diagnosis is by histopathology and of the immunohistochemical profile. We describe a case of nodular fasciitis in the oral cavity that demonstrated partial spontaneous regression. The patient was a 32-year-old man with a buccal mucosal mass, which had grown rapidly for 45 days. On microscopic examination, the lesion displayed a well-delineated but not encapsulated proliferation of spindle cells, with a nodular growth pattern. Immunohistochemical analysis showed positivity of the spindle cells for the antibodies against smooth muscle actin and muscle-specific actin (HHF-35). Treatment of such lesions typically involves complete conservative excision, but the lesion may regress eventually in the absence of definitive treatment.
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- Titel
- Nodular Fasciitis of the Oral Cavity with Partial Spontaneous Regression (Nodular Fasciitis)
- Verfasst von
-
Marina Lara de Carli
Karin Sá Fernandes
Décio dos Santos Pinto Jr.
Andrea Lusvarghi Witzel
Marília Trierveiler Martins
- Publikationsdatum
- 01.03.2013
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 1/2013
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-012-0390-3
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