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13.03.2024 | Original Contributions

Nomogram for Predicting Remission of Metabolic Syndrome 1 Year after Sleeve Gastrectomy Surgery in Chinese Patients with Obesity

verfasst von: Yunhui Pan, Xiaodong Han, Yinfang Tu, Pin Zhang, Haoyong Yu, Yuqian Bao

Erschienen in: Obesity Surgery | Ausgabe 5/2024

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Abstract

Purpose

Sleeve gastrectomy (SG) is a widely used and effective treatment for patients with obesity and comorbid metabolic abnormalities. No specialized tool is available to predict metabolic syndrome (MS) remission after SG. We presented a nomogram that evaluated the probability of MS remission in obese patients 1 year after SG.

Materials and Methods

Patients with preoperative MS who underwent SG were enrolled in this retrospective study. They were divided into a training set and a validation set. Multivariate logistic regression analysis was performed to identify independent predictors of MS remission, and these predictors were included in the nomogram. Receiver operating characteristic curve was used to evaluate discrimination. Calibration was performed with the Hosmer–Lemeshow goodness-of-fit test. The net benefits of the nomogram were evaluated using decision curve analysis (DCA).

Results

Three hundred and eighteen patients with a median age of 34.0 years were analyzed. A training set and a validation set with 159 individuals each were established. A combination of age, preoperative high-density lipoprotein cholesterol, elevated triglycerides and glycated hemoglobin level independently and accurately predicted MS remission. The nomogram included these factors. The discriminative ability was moderate in training and validation sets (Area under curve 0.800 and 0.727, respectively). The Hosmer–Lemeshow X2 value of the nomogram was 8.477 (P = 0.388) for the training set and 5.361 (P = 0.718) for the validation set, indicating good calibration. DCA showed the nomogram had clinical benefits in both datasets.

Conclusion

Our nomogram could accurately predict MS remission in Chinese patients with obesity 1 year after SG.

Graphical Abstract

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Metadaten
Titel
Nomogram for Predicting Remission of Metabolic Syndrome 1 Year after Sleeve Gastrectomy Surgery in Chinese Patients with Obesity
verfasst von
Yunhui Pan
Xiaodong Han
Yinfang Tu
Pin Zhang
Haoyong Yu
Yuqian Bao
Publikationsdatum
13.03.2024
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 5/2024
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-024-07156-x

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