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24.09.2020 | Original Article

Non-radiographic axial spondyloarthritis in Tunisia: main characteristics and detailed comparison with ankylosing spondylitis

verfasst von: Kawther Ben Abdelghani, Yosra Gzam, Alia Fazaa, Saoussen Miladi, Meriem Sellami, Leila Souabni, Selma Kassab, Selma Chekili, Leith Zakraoui, Ahmed Laater

Erschienen in: Clinical Rheumatology | Ausgabe 4/2021

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Abstract

Objectives

The aim of the present study is to compare the clinical features, disease activity, and physical impairment between non-radiographic axial spondyloarthritis and ankylosing spondylitis in Tunisian patients.

Methods

This is a retrospective study conducted in a single rheumatology center in Tunisia. Patients with axial spondyloarthritis fulfilling the 2009 ASAS criteria were included. The various spondyloarthritis-related variables were compared between non-radiographic axial spondyloarthritis and ankylosing spondylitis. p Values below 0.05 were considered statistically significant.

Results

Among 200 patients with axial spondyloarthritis, 40 had non-radiographic axial spondyloarthritis and 160 had ankylosing spondylitis. The non-radiographic axial spondyloarthritis patients were more frequently female, were younger, and had shorter disease duration. Patients with non-radiographic axial spondyloarthritis experienced enthesitis more frequently compared with ankylosing spondylitis patients. Psoriasis was more frequent in non-radiographic axial spondyloarthritis group, while inflammatory bowel disease was more frequent in ankylosing spondylitis group. The C-reactive protein level and functional score were significantly higher in patients with ankylosing spondylitis compared with non-radiographic axial spondyloarthritis. Tumor necrosis factor inhibitors were offered significantly more often to the ankylosing spondylitis group. There was no statistically significant difference between the 2 groups in other spondyloarthritis parameters.

Conclusion

The non-radiographic axial spondyloarthritis is characterized mainly by a marked female prevalence, a higher enthesitis prevalence, and a better physical function.

Key points:

• Patients with nr-axSpA in Tunisia are more frequently female and have shorter disease duration compared with those with AS.

• Peripheral manifestations were similar between nr-axSpA and AS patients except for enthesitis which were more frequent within nr-axSpA patients.

• The disease activity is similar between the 2 groups of axSpA but the physical function is better within nr-axSpA patients.

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Titel: Non-radiographic axial spondyloarthritis in Tunisia: main characteristics and detailed comparison with ankylosing spondylitis
verfasst von: Kawther Ben Abdelghani
Yosra Gzam
Alia Fazaa
Saoussen Miladi
Meriem Sellami
Leila Souabni
Selma Kassab
Selma Chekili
Leith Zakraoui
Ahmed Laater
Publikationsdatum: 24.09.2020
Verlag: Springer International Publishing
Erschienen in: Clinical Rheumatology / Ausgabe 4/2021
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-020-05415-7

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Non-radiographic axial spondyloarthritis in Tunisia: main characteristics and detailed comparison with ankylosing spondylitis

Abstract

Objectives

Methods

Results

Conclusion

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Parodontalbehandlung verbessert Prognose bei Katheterablation

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Denken Sie bei starker Blutung auch an die Hemmkörper-Hämophilie

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Abstract

Objectives

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Conclusion

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