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Head and Neck Pathology

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21.03.2019 | Original Paper

Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features is Rare: A Population Based Study of Incidence

verfasst von: Rasmus H. Reinke, Stine R. Larsen, Jes S. Mathiesen, Christian Godballe, Stefano C. Londero

Erschienen in: Head and Neck Pathology | Ausgabe 1/2020

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Abstract

The renaming of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was proposed by a group of experts in 2016 to prevent overtreatment of indolent, low-risk thyroid cancers. The aim of this study was to estimate the incidence and outcome for patients meeting the NIFTP criteria in a well-defined geographic region. Our cohort consisted of 134 patients with papillary thyroid carcinoma from the Region of Southern Denmark (RSD), 2007 to 2011. Patients were retrieved from the Danish Thyroid Cancer (DATHYRCA) Database. All potential NIFTP cases were reviewed by a thyroid pathologist. We identified no cases meeting all diagnostic criteria, but one probable NIFTP case from 2007 to 2011. The patient was treated according to the national guidelines and is alive and recurrence-free after 106 months of follow-up. Molecular testing showed KRAS mutation. In a population based set up the incidence rate of NIFTP is very low.

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Titel: Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features is Rare: A Population Based Study of Incidence
verfasst von: Rasmus H. Reinke
Stine R. Larsen
Jes S. Mathiesen
Christian Godballe
Stefano C. Londero
Publikationsdatum: 21.03.2019
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2020
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-019-01032-2

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01.04.2024 | Forensische Traumatologie | CME

Springer Medizin

Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features is Rare: A Population Based Study of Incidence

Abstract

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Abstract

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