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Current Heart Failure Reports

Erschienen in:

06.04.2018 | Pharmacologic Therapy (W.H.W. Tang, Section Editor)

Novel Insights and Treatment Strategies for Right Heart Failure

verfasst von: Weiqin Lin, Ai-Ling Poh, W. H. Wilson Tang

Erschienen in: Current Heart Failure Reports | Ausgabe 3/2018

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Abstract

Purpose of Review

The function of the right ventricle (RV) is intimately linked to its preload (systemic volume status) and afterload (pulmonary vasculature). In this review, we explore current knowledge in RV physiology, RV function assessment, causes of right heart failure (RHF), and specific treatment strategies for RHF.

Recent Findings

We examine the evidence behind new pharmacological therapies available, such as macitentan and riociguat in the treatment of specific etiologies of RHF. We will also focus on RHF in the setting of heart failure with preserved ejection fraction (HFpEF) and in the presence of left ventricular assist devices (LVAD), looking at current treatment recommendations, including mechanical circulatory support. Lastly, we will look to the horizon for the latest research on RHF, including the molecular basis of RHF and potential novel treatment methods for this old yet poorly understood syndrome.

Summary

Disturbances in this complex relationship result in the clinical syndrome of RHF. Despite advances in the management of left heart diseases, much work remains to be done to understand and manage RHF.

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Titel: Novel Insights and Treatment Strategies for Right Heart Failure
verfasst von: Weiqin Lin
Ai-Ling Poh
W. H. Wilson Tang
Publikationsdatum: 06.04.2018
Verlag: Springer US
Erschienen in: Current Heart Failure Reports / Ausgabe 3/2018
Print ISSN: 1546-9530
Elektronische ISSN: 1546-9549
DOI: https://doi.org/10.1007/s11897-018-0389-5

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Springer Medizin

Novel Insights and Treatment Strategies for Right Heart Failure

Abstract

Purpose of Review

Recent Findings

Summary

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Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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