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Erschienen in:

01.11.2018 | Neuro-oncology (R Soffietti, Section Editor)

Novel Systemic Treatments for Brain Metastases From Lung Cancer

verfasst von: Bicky Thapa, MD, Adam Lauko, BS (Medical Student), Kunal Desai, MD, Vyshak Alva Venur, MD, Manmeet S. Ahluwalia, MD, FACP

Erschienen in: Current Treatment Options in Neurology | Ausgabe 11/2018

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Abstract

Purpose of review

Brain metastases are frequent complication of lung cancer and are associated with poor prognosis. Patients with brain metastases secondary to lung cancer have traditionally been managed with surgery and radiation with limited role for systemic chemotherapy. In the past decade, however, this paradigm has shifted largely due to the advent of targeted therapies and immunotherapies, both of which have demonstrated efficacy in the treatment of brain metastases and extracranial disease.

Recent findings

While patients with brain metastases secondary to lung cancer have historically been excluded from trials, recent data suggest efficacy of novel targeted therapies and immunotherapies in these patients. In fact, there are multiple ongoing trials to further evaluate these therapies in this patient profile.

Summary

Targeted therapies and immunotherapies have the potential to improve outcomes in patients with brain metastases secondary to lung cancer.

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Titel: Novel Systemic Treatments for Brain Metastases From Lung Cancer
verfasst von: Bicky Thapa, MD
Adam Lauko, BS (Medical Student)
Kunal Desai, MD
Vyshak Alva Venur, MD
Manmeet S. Ahluwalia, MD, FACP
Publikationsdatum: 01.11.2018
Verlag: Springer US
Erschienen in: Current Treatment Options in Neurology / Ausgabe 11/2018
Print ISSN: 1092-8480
Elektronische ISSN: 1534-3138
DOI: https://doi.org/10.1007/s11940-018-0533-2

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25.04.2024 | Hypotonie | Nachrichten

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Springer Medizin

Novel Systemic Treatments for Brain Metastases From Lung Cancer

Abstract

Purpose of review

Recent findings

Summary

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Neurologie

Springer Medizin

Abstract

Purpose of review

Recent findings

Summary

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Sleep Abnormalities in Wilson’s Disease

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Managing Antiepileptic Medication in Dialysis Patients

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Update Neurologie