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Reviews in Endocrine and Metabolic Disorders
Erschienen in: Reviews in Endocrine and Metabolic Disorders 3/2016

10.11.2016

Obesity as a risk factor for malignant melanoma and non-melanoma skin cancer

verfasst von: K. Karimi, T. H. Lindgren, C. A. Koch, Robert T. Brodell

Erschienen in: Reviews in Endocrine and Metabolic Disorders | Ausgabe 3/2016

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Abstract

The dramatic increases in incidence of both obesity and many cancers including skin cancer emphasize the need to better understand the pathophysiology of both conditions and their connections. Melanoma is considered the fastest growing cancer and rates of non-melanoma skin cancer have also increased over the last decade. The molecular mechanisms underlying the association between obesity and skin cancer are not clearly understood but emerging evidence points to changes in the tumor microenvironment including aberrant cell signaling and genomic instability in the chronic inflammatory state many obese individuals experience. This article reviews the literature linking obesity to melanoma and non-melanoma skin cancer.
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Metadaten
Titel
Obesity as a risk factor for malignant melanoma and non-melanoma skin cancer
verfasst von
K. Karimi
T. H. Lindgren
C. A. Koch
Robert T. Brodell
Publikationsdatum
10.11.2016
Verlag
Springer US
Erschienen in
Reviews in Endocrine and Metabolic Disorders / Ausgabe 3/2016
Print ISSN: 1389-9155
Elektronische ISSN: 1573-2606
DOI
https://doi.org/10.1007/s11154-016-9393-9

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