Professor Emeritus Haruto Uchino passed away on 29 January at the age of 83. He was a man of deep foresight, and yet I vividly remember him pointing out a Kaiser–Fleisher ring in a patient who later turned out to have Wilson’s disease. On one of his rounds, he quickly discovered the presence of a gravitation abscess on the chest wall of a febrile patient just by physical examination. He used to stress the importance of history-taking and physical diagnosis in internal medicine. “Of vital importance is understanding the entire spectrum of a single disease. The best example is pernicious anemia, historically regarded as a form of refractory anemia; it is basically an autoimmune abnormality affecting the gastric mucosal absorption of vitamin B12.” (Preface to Pathophysiology of Internal Medicine, edited by Dr. Uchino).
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