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Documenta Ophthalmologica

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01.02.2013 | Original Research Article

Objective assessment of the human visual attentional state

verfasst von: Kevin T. Willeford, Kenneth J. Ciuffreda, Naveen K. Yadav, Diana P. Ludlam

Erschienen in: Documenta Ophthalmologica | Ausgabe 1/2013

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Abstract

Primary objective

The purpose of this study was to develop an objective way to assess human visual attention using the alpha-band component of the visual-evoked potential (VEP).

Design and methods

Six different attentional conditions were tested: eyes-open, eyes-closed, eyes-closed with backwards number counting, and three rapid-serial visual presentation (RSVP) tasks. Eighteen visually normal, young-adult subjects (ages 21–28 years) were tested binocularly at 1 m for each condition on two separate days. The Diopsys™ NOVA-TR system was used to obtain the visual-evoked potential (VEP) and extracted alpha wave and its related power spectrum. Additionally, the Visual Search and Attention Test (VSAT) was administered as a subjective measure of visual attention.

Results

Subjects exhibited significant decreases in power in the alpha band when comparing the eyes-closed with the eyes-open conditions, with power in the eyes-closed condition being, on average, twice as large. The response from the other four conditions did not reflect the differential attentional demands. The ratio of the power in the eyes-closed condition to the eyes-open condition in the lower-alpha frequencies (8–10 Hz) was found to be significantly correlated with the group’s performance on the VSAT, especially the 10-Hz component.

Conclusions

An individual’s ability to attenuate their alpha component during visual processing may be a predictor of their visual attentional state. These findings solidify the role of the VEP alpha subcomponent as an objective electrophysiological correlate of visual attention, which may be useful in the diagnosis and treatment of human visual attention disorders in the future.

Odom JV, Bach M, Brigell M, Holder GE, McCulloch DL, Tormene AP, Vaegan (2010) ISCEV standard for clinical visual-evoked potentials (2009 update). Doc Ophthalmol 120:111–119PubMedCrossRef

Yadav NK, Almogbel F, Head L, Irving EL, Leat SJ (2009) Threshold determination in sweep VEP and the effects of criterion. Doc Ophthalmol 119:109–121PubMedCrossRef

Almoqbel FM, Yadav NK, Leat SJ, Head LM, Irving EL (2011) Effects of sweep VEP parameters on visual acuity and contrast thresholds in children and adults. Graefes Arch Clin Exp Ophthalmol 249:613–623PubMedCrossRef

Politzer T, Suter PS (2011) Vision examination of patients with neurological disease and injury. In: Suter PS, Harvey LH (eds) Vision rehabilitation: multidisciplinary care of the patient following brain injury. Taylor and Francis Group, Boca Raton, pp 427–460CrossRef

Berger H (1929) Ueber des elektrenkephelogramm des menschen. Arch Psychiat Nervenkr 87:527–570CrossRef

Klimesch W (1999) EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis. Brain Res 29:169–195CrossRef

Feige B, Scheffler K, Esposito F, Di Salle F, Jurgen H, Seifritz E (2005) Cortical and subcortical correlates of electroencephalographic alpha rhythm modulation. J Neurophysiol 93:2864–2872PubMedCrossRef

Gomarus HK, Wijers AA, Minderaa RB, Althaus M (2009) Do children with ADHD and/or PDD-NOS differ in reactivity of alpha/theta ERD/ERS to manipulations of cognitive load and stimulus relevance? Clin Neurophysiol 120:73–79PubMedCrossRef

Luria AR (1966) Higher cortical functions in man. Basic Books, New York

10.

Niedermeyer E, Lopes da Silva F (eds) (1993) Electroencephalogrpahy: basic principles, clinical applications, and related fields, 3rd edn. Williams and Wilkins, Baltimore

11.

Ludlam WM (1976) Review of psycho-physiological factors in visual information processing as they relate to learning. In: Greenstein T (ed) Vision and learning disability. J Am Optom Assoc, St Louis, pp 179–222

12.

Ludlam WM (1979) Visual training, the alpha activation cycle, and reading. J Am Optom Assoc 50:111–115PubMed

13.

Babiloni F, Cincotti F, Babiloni C, Carducci F, Mattia D, Astolfi L, Basilisco A, Rossini PM, Ding L, Ni Y, Cheng J, Christine K, Sweeney J, He B (2005) Estimation of the cortical functional connectivity with the multimodal integration of high-resolution EEG and fMRI data by directed transfer function. Neuroimage 24:118–131PubMedCrossRef

14.

Adrian ED, Matthews BHC (1934) The Berger rhythm: potential changes from the occipital lobes in man. Brain 57:355–385CrossRef

15.

Gale A, Coles M, Boyd E (1971) Variation in visual input and the occipital EEG. Psychon Sci 23:99–100

16.

Mann CA, Sterman MB, Kaiser DA (1996) Suppression of EEG rhythmic frequencies during somato-motor and visuo-motor behavior. Int J Psychophysiol 23:1–7PubMedCrossRef

17.

Legewie H, Simonova O, Creutzfeldt OD (1969) EEG changes during performance of various tasks under open and closed-eyed conditions. Electroencephalogr Clin Neurophysiol 27:470–479PubMedCrossRef

18.

Gotman J, Wang LY (1991) State-dependent spike detection: concepts and preliminary results. Electroencephalogr Clin Neurophysiol 79:11–19PubMedCrossRef

19.

Kopruner V, Pfurtscheller G, Auer LM (1984) Quantitative EEG in normals and in patients with cerebral ischemia. In: Pfurtscheller G, Jonkman EJ, Lopes da Silva FH (eds) Brain ischemia: quantitative EEG and imaging techniques, progress in brain research, vol 62. Elsevier, New York, pp 29–50

20.

Helvie R (2011) Neural substrates of vision. In: Suter PS, Harvey LH (eds) Vision rehabilitation: multidisciplinary care of the patient following brain injury. Taylor and Francis Group, Boca Raton, pp 45–76CrossRef

21.

American Clinical Neurophysiology Society (2006) Guideline 5: guidelines for standard electrode position nomenclature. J Clin Neurophysiol 23:107–110CrossRef

22.

Walter WG (1963) The living brain. WW Norton and Co Inc, New York

23.

Ciuffreda KJ (2002) The scientific basis for and efficacy of optometric vision therapy in nonstrabismic accommodative and vergence disorders. Optometry 73:735–762PubMed

24.

Solan HA, Shelley-Tremblay J, Ficarra A, Silverman M, Larson S (2003) Effect of attention therapy on reading comprehension. J Learn Disabil 36:556–563PubMedCrossRef

25.

Fuller P (1978) Attention and the EEG alpha rhythm in learning disabled children. J Learn Disabil 11:303–312PubMedCrossRef

26.

Yadav NK, Ludlam DP, Ciuffreda KJ (2012) Effect of different stimulus configurations on the visual evoked potential (VEP). Doc Ophthalmol 124:177–196PubMedCrossRef

27.

Ciuffreda KJ, Yadav NK, Ludlam DP (2012) Effect of binasal occlusion (BNO) on the visual-evoked potential (VEP) in mild traumatic brain injury (mTBI). Brain Inj (in press)

28.

Trenerry MR, Crosson B, DeBoe J, Leber WR (1989) Professional manual: visual search and attention test. Psychological Assessment Resources, Lutz

29.

Benjamin WJ (2006) Borish’s Clinical Refraction (2nd edn). Butterworth-Heinemann, St. Louis

30.

Smith A (1967) The serial sevens subtraction test. Arch Neurol 17:78PubMedCrossRef

31.

Bradley JV (1958) Complete counterbalancing of immediate sequential effects in a latin square design. J Am Stat Assoc 53:525–528CrossRef

32.

Squires N, Squires K, Hillyard S (1975) Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. Electroencephalogr Clin Neurophysiol 38:387–401PubMedCrossRef

33.

Dumermuth G (1987) Spectral analysis of the EEG. Neuropsychobiology 17:85–99PubMedCrossRef

34.

Salkind N (ed) (2010) Encyclopedia of research design. Sage, Thousand Oaks

35.

Maltez J, Hyllienmark L, Nikulin VV, Brismar T (2004) Time course and variability of power in different frequency bands of EEG during resting conditions. Clin Neurophysiol 34:195–202CrossRef

36.

Chiappa KH (1990) Evoked potentials in clinical medicine. Raven Press, New York

37.

Doppelmayr M, Klimesch W, Pachinger T, Ripper B (1998) The functional significance of absolute power with respect to event-related desynchronization. Brain Topogr 11:133–140PubMedCrossRef

38.

Mann CA, Lubar JF, Zimmerman AW, Miller CA, Muenchen RA (1992) Quantitative analysis of EEG in boys with attention-deficit-hyperactivity disorder: controlled study with clinical implications. Pediatr Neurol 8:30–36PubMedCrossRef

39.

Conners KC (2004) Conners’ continuous performance test II [manual]. Multi-Health Systems Inc, Toronto

40.

Suchoff IB, Ciuffreda KJ, Kapoor N (eds) (2001) Visual and vestibular consequences of acquired brain injury. Optometric Extension Program, Santa Ana

41.

Chabot R, Serfontein G (1996) Quantitative electroencephalographic profiles of children with attention deficit disorder. Biol Psychiatry 40:951–963PubMedCrossRef

42.

Clarke AR, Barry RJ, McCarthy R, Selikowitz M (1998) EEG analysis in attention-deficit/hyperactivity disorder: a comparative study of two subtypes. Psychiatry Res 81:19–29PubMedCrossRef

43.

Somers DC, Dale AM, Seiffert AE, Tootell RBH (1999) Functional MRI reveals spatially specific attentional modulation in human primary visual cortex. Proc Natl Acad Sci USA 96:1663–1668PubMedCrossRef

44.

Herrero JL, Roberts MJ, Delicato LS, Gieselmann MA, Dayan P, Thiele A (2008) Acetylcholine contributes through muscarinic receptors to attentional modulation in V1. Nature 454:1110–1114PubMedCrossRef

45.

Bollimunta A, Mo J, Schroeder CE, Ding M (2011) Neuronal mechanisms and attentional modulation of corticothalamic alpha oscillations. J Neurosci 31:4935–4943PubMedCrossRef

46.

Lopes da Silva FH, Vos JE, Mooibroek J, Van Rotterdam A (1980) Relative contributions of intracortical and thtalamocortical processes in the generation of alpha rhythms, revealed by partial coherence analysis. Electroencephalogr Clin Neurophysiol 50:449–456PubMedCrossRef

47.

Hughes SW, Crunelli V (2007) Just a phase they’re going through: the complex interaction of intrinsic high-threshold bursting and gap junctions in the generation of thalamic alpha and theta rhythms. Int J Psychophysiol 64:3–17PubMedCrossRef

48.

Tineke G, Boehler CN, Kenemans JL, Woldorff MG (2011) Differential functional roles of slow-wave and oscillatory alpha activity in visual sensory cortex during anticipatory visual-spatial attention. Cereb Cortex 21:2204–2216CrossRef

49.

Kelly SP, Gomez-Ramirez M, Foxe JJ (2009) The strength of anticipatory spatial biasing predicts target discrimination at attended locations: a high-density EEG study. Eur J Neurosci 30:2224–2234PubMedCrossRef

50.

van Dijk H, Schoffelen JM, Oostenveld R, Jensen O (2008) Prestimulus oscillatory activity in the alpha band predicts visual discrimination ability. J Neurosci 28:1816–1823PubMedCrossRef

51.

Hanslmayr S, Aslan A, Staudigl T, Klimesch W, Hermann CS, Bäuml CH (2007) Prestimulus oscillations predict visual perception performance between and within subjects. Neuroimage 37:1465–1473PubMedCrossRef

52.

Tello C, De Moraes CGV, Prata TS, Derr P, Patel J, Siegfried J, Liebmann JM, Ritch R (2010) Repeatability of short-duration transient visual evoked potentials in normal subjects. Doc Ophthalmol 120:219–228PubMedCrossRef

53.

Arciniegas DB (2011) Clinical electrophysiological assessments and mild traumatic brain injury: state-of-the-science and implications for clinical practice. Int J Psychophysiol 82:41–52PubMedCrossRef

54.

Ciuffreda KJ, Tannen B (1995) Eye movement basics for the clinician. Mosby-Year Book Inc, St. Louis

55.

Corbetta M, Shulman GL (2002) Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3:201–215PubMedCrossRef

Titel: Objective assessment of the human visual attentional state
verfasst von: Kevin T. Willeford
Kenneth J. Ciuffreda
Naveen K. Yadav
Diana P. Ludlam
Publikationsdatum: 01.02.2013
Verlag: Springer-Verlag
Erschienen in: Documenta Ophthalmologica / Ausgabe 1/2013
Print ISSN: 0012-4486
Elektronische ISSN: 1573-2622
DOI: https://doi.org/10.1007/s10633-012-9357-7

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Objective assessment of the human visual attentional state

Abstract

Primary objective

Design and methods

Results

Conclusions

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Springer Medizin

Abstract

Primary objective

Design and methods

Results

Conclusions

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