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Clinical Research in Cardiology

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16.06.2016 | Original Paper

Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study

verfasst von: T. M. Berghaus, A. Witkowska, T. Wagner, C. Faul, M. Schwaiblmair, W. von Scheidt

Erschienen in: Clinical Research in Cardiology | Ausgabe 11/2016

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Abstract

Background

Obstructive sleep apnea (OSA) might be an independent risk factor for acute pulmonary embolism (APE).

Aim of the study

A prospective cohort study was conducted to investigate if APE is sleep-related in untreated OSA syndrome or not.

Methods

206 APE patients were evaluated by portable monitoring and polysomnography. APE symptoms which caused an arousal from sleep or occurred within the first hour after wake-up were considered to be sleep-related.

Results

APE manifestation is significantly more often sleep-related in patients with moderate or severe OSA compared to subjects with an apnea–hypopnea index ≤15/h (p < 0.001). The relative risk of sleep-related APE increases with the severity of OSA.

Conclusions

OSA might trigger APE, possibly reflecting a pathophysiological relationship between these two conditions.

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Titel: Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study
verfasst von: T. M. Berghaus
A. Witkowska
T. Wagner
C. Faul
M. Schwaiblmair
W. von Scheidt
Publikationsdatum: 16.06.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Research in Cardiology / Ausgabe 11/2016
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-016-1002-0

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Obstructive sleep apnea might trigger acute pulmonary embolism: results from a cohort study

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Aim of the study

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Results

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