Occupational Argyria of the Nasal Mucosa
- 04.08.2017
- Sine qua non Clinicopathologic Correlation
- Verfasst von
-
Gerardo Ferrara
Korrespondierender Autor Gerardo Ferrara
- Anatomic Pathology Unit, Macerata General Hospital, 62100, Macerata, Italy
-
Alessandra Filosa
Alessandra Filosa
- Anatomic Pathology Unit, Macerata General Hospital, 62100, Macerata, Italy
-
Maria Paola Mariani
Maria Paola Mariani
- Anatomic Pathology Unit, Macerata General Hospital, 62100, Macerata, Italy
-
Luigi Fasanella
Luigi Fasanella
- Otorhyniloaryngology Unit, Civitanova Marche General Hospital, Civitanova Marche, Italy
- Erschienen in
- Head and Neck Pathology | Ausgabe 2/2018
Abstract
A biopsy specimen from the nasal mucosa of a 37-year-old man disclosed a subepithelial accumulation of black granules mainly running parallel to the surface in the absence of any inflammatory infiltrate. Since the mucosal pigment was negative with Perls’ stain and resisted to melanin bleach, an exogenous pigmentation was suspected. The biopsy specimen had been taken because of a diffuse steel-blue pigmentation of the nasal mucosa, incidentally discovered during routine clinical examination. A diagnosis of occupational argyria of the nasal mucosa was finally made since the patient was a silver cleaner. Argyria is a rare cause of nasopharyngeal mucosal pigmentation; it is not a precancerous condition, but it can be mistaken for a melanosis or a melanocytic tumor both clinically and histopathologically. Clinicopathological correlation is mandatory, since the final diagnosis is based on a history of chronic silver exposure.
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- Titel
- Occupational Argyria of the Nasal Mucosa
- Verfasst von
-
Gerardo Ferrara
Alessandra Filosa
Maria Paola Mariani
Luigi Fasanella
- Publikationsdatum
- 04.08.2017
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 2/2018
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-017-0842-x
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